Research

Funding: Niedersächsisches Ministerium für Wissenschaft und Kultur Volkswagenstiftung, 75.000 EUR

Project Details:
Various studies have already shown effects of chemicals from everyday products on the environment and health. The European Green Deal therefore aims to better assess the risks of hazardous chemicals and in particular very persistent chemicals in a timely manner. Pollution from persistent and mobile chemicals is closely linked to prevailing production and consumption patterns and is determined by the lack of appropriate technical options. These chemicals also challenge regulators to develop and enforce effective policies. The project aimed at increasing knowledge on health and environmental effects on aquatic and terrestrial wildlife. In addition to developing solutions for monitoring, a better understanding of the accumulation of these chemicals in the environment, in line with the EU call with the planned research project, should also help to proactively prevent negative impacts of persistent and mobile chemicals on humans and the environment.
The project serves to build and consolidate a project consortium to ensure the project application and a joint timely application in this EU funding programme. The involvement of many European countries in the project consortium should make it possible to write the project proposal with experienced scientists from the fields of toxicology and health and to submit it on time with an external professional office for EU project applications.

Results:

In the project, a project consortium was established to ensure a project proposal and a joint timely application in this EU funding program. The involvement of many European countries in the project consortium made it possible to write the project application with experienced scientists from the fields of toxicology and health and to submit it on time with an external professional office for EU project applications.

Funding: Landwirtschaftliche Rentenbank, 50.000 EUR

Project Details:
The projects`main question is if, why and how the welfare of farm animals is connected to the idea of sustainability and if animals`interests are playing a role in the present discussions on sustainability.

Results:

In current sustainability concepts, animals and animal welfare are only indirectly addressed in places, although this preliminary study has shown that their inclusion is socially desirable or even demanded. The extent to which the anthropocentric sustainability goals and the welfare of farm animals can be meaningfully linked will be the subject of a follow-up project.

Funding: Niedersächsisches Ministerium für Wissenschaft und Kultur, 116.300 EUR

Project Details:
Neozoa are alien or non-native animal species that have been directly or indirectly introduced into a new habitat by humans. Intentional and unintentional introductions pose a threat to biodiversity worldwide. One prominent example is the raccoon. This problem is well known and is taken into account in Germany, for example, in the Federal Nature Conservation Act and the National Biodiversity Strategy. However, it is often unclear how introduced animal species should be dealt with. Prevention is the top priority. The aim is to prevent new species from being introduced and spreading. However, depending on the species and the invasiveness assessment by the Federal Agency for Nature Conservation, animals are also removed and killed. This leads to a conflict between animal welfare, species protection and environmental protection. Although animal-related issues are usually discussed very emotionally, this problem has so far only been partially recognized by the public. For this reason, this area of conflict will be addressed during the project and discussed with various interest groups. The focus will be on two projects of the Institute for Terrestrial and Aquatic Wildlife Research of the University of Veterinary Medicine Hannover Foundation, which deal with the introduction of the nutria, originally from South America.

Results:

Gethöffer, F.; Kirberg, S.; Schöttes, F.; Siebert, U. Der Umgang mit Neozoen: ein gesellschaftlicher Diskurs. Naturschutz und Landschaftsplanung 2022, 54 (6), 30-36. https://doi.org/10.1399/NuL.2022.06.03.

https://doi.org/10.1399/NuL.2022.06.03

Funding: Niedersächsisches Ministerium für Wissenschaft und Kultur, 49.945 EUR

Project Details:
Modul 1: Online-Betreuungsmodul im Lernmanagementsystem Moodle
- Moderiertes Forum und online-Frage-Sprechstunden
- Studierende können Fallbeispiele aus ihrem Praktikum hochladen, die vom Betreuer geprüft und beantwortet, kommentiert und dann bei Eignung dem gesamten Kurs zur Verfügung gestellt werden
- Selbstlernangebot durch Bereitstellung von begleitenden Materialien (Skript, Gesetzestexte, Bildmaterial, Fallbeispiele, Anleitung zur Reflexion und Achtsamkeit und zu Resilienztraining)
Modul 2: Offline-Betreuungsmodul unter anderem vor Ort im Schlachthof
-Fokusgruppengespräch mit Studierenden (Bedarfsermittlung)
-Besuch der Studierenden in ihren Praktikumsstätten über einen Zeitraum von 8 Monaten (diverse Schlachthöfe)
-Leitfadengestützte Interviews mit Studierenden im Schlachthof (Situationen und Fragestellungen werden aufgearbeitet und dokumentiert)

Project Details:
Addition of antibiotics to semen extenders is required to control the growth of commensale bacteria in animal semen. Follwing the One Health concept and the DART strategy for reduction of antibiotics, alternative antimicrobial strategies in preserved boar semen are tested.

Project Details:
Boar spermatozoa are sensitive to cooling and, therefore, commonly are preserved at 16°C for use in artificial insemination (AI). Recently, hypothermic semen preservation at 5°C was established to reduce the risk for bacterial growth and to stabilize transport conditions. The aim is to assess the eligibility of AI boars for hypothermic semen preservation using conventional spermatology.

Cooperation Partners:

Hochschule Osnabrück

GfS Ascheberg

Funding: Industry (Veterinary pharmaceuticals/Vaccines), 550.000 EUR

Project Details:
confidential

Results:

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1274-9268

Project Details:
As part of this project, a computer model of the canine hind limbs is being developed on the basis of CT and MRT data. In addition to bony structures, this model should also map muscle and ligament structures in order to subsequently be able to simulate movements of the canine hind limbs.

Results:

https://doi.org/10.1016/j.rvsc.2021.03.015

Project Details:
Motile sperm with intact membranes can suffer from functional damage which remains undetected by routine semen analysis. For assessment of novel semen preservation methods, sensitive diagnostic of fertility-relevant functional sperm traits is neccessary. The aim is to establish novel diagnostic tools which allow the sensitive assessment of sublethal damage of preserved spermatozoa.

Results:

DOI: 10.1002/cyto.a.24301

Cooperation Partners:

Dr. Heiko Henning, Friedrich-Loeffler-Institut Mariensee

Funding: Epilepsy Foundation, 200.000 EUR

Project Details:
Tuberous sclerosis complex (TSC) is a genetic disease, which leads to elevated PI3K/mTOR signaling and causes development of tumors in different organs as well as epileptic seizures, developmental delay, and autism. Therapy is limited to often ineffective anti-seizure drugs (ASDs), surgery, and rapalogs (everolimus), the first generation mTOR inhibitors. Recently, everolimus has been approved for treatment of ASD-refractory partial-onset seizures in patients with TSC. However, this therapy is associated with severe adverse events, including immunosuppression. We have developed novel, ATP-competitive, specific, brain penetrant mTOR and PI3K/mTOR inhibitors, which have a much better safety profile; particularly these compounds lack immunosuppressive activity.

Cooperation Partners:

PIQUR, Basel, Schweiz