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2235 results.
Development of antimicrobial resistance of Actinobacillus-pleuropneumoniae-isolates from routine diagnostics since 2006 and coinfecting agents involved in disease pathogenesis
Resistenzentwicklung von Actinobacillus pleuropneumoniae Isolaten aus der Rotinediagnostik seit 2006 sowie an der Erkrankung beteiligte Koinfektionserreger
Project Investigators: Isabel Hennig-Pauka; Lothar Kreienbrock; Maria Hartmann; Jörg Merkel
Duration: January 2021 until May 2022
Project Details:
Frequencies of Actinobacillus pleuropneumoniae isolates resistant against various antimicrobial substances will be compared in the years 2006-2021. Frequencies of coinfecting agents will be determined.
Results:

doi: 10.3389/fvets.2021.802570

Show Details
Investigation of the effect of Solanum glaucophyllum crude extract (SG crude extract) on cell viability of Caco-2 cells as a model of the small intestine.
Untersuchungen der Auswirkung von Solanum glaucophyllum Rohextrakt (SG-Rohextrakt) auf die Zellviabilität von Caco-2 Zellen als Modell des Dünndarms
Project Investigators: Pascal Hoffmann; Nadine Schnepel
Duration: December 2021 until February 2022
Funding: Herbonis Animal Health GmbH Rheinstrasse 30 4302 Augst BL, Schweiz, 4.300 EUR
Project Details:
Solanum glaucophyllum (waxy nightshade) is one of the few plants that naturally produces 1,25-dihydroxycholecalciferol glycosides (1,25(OH)2D3-gly). In the literature it is mentioned that the glycosides are cleaved before absorption and thus only the aglycone is absorbed. However, no data are known so far that confirm this assumption analytically. In a multi-stage approach, this question is to be clarified in vitro. To do this, a number of preliminary tests must first be carried out, including one focusing on possible cell toxicity. Since the cell toxicity of 1,25(OH)2D3-gly can only be extrapolated from the data for synthetic 1,25(OH)2D3 to a limited extent, this experiment serves to determine the maximum possible dose.
Cooperation Partners:

Herbonis Animal Health GmbH

Rheinstrasse 30

4302 Augst BL, Schweiz

Show Details
Aerial Survey of grey seals in the Wadden Sea of Lower Saxony and Hamburg-2021/2022
Kegelrobben-Kartierung im Niedersächsischen und Hamburgischen Wattenmeer per Flugzeug 2021/2022
Project Investigators: Prof. Prof. h. c. Dr. Ursula Siebert; Dr. Abbo van Neer
Duration: Novemer 2021 until September 2022
Funding: Nationalparverwaltung "Nieders. Wattenmeer" Wilhelmshaven, 39.080 EUR
Project Details:
The aim of the project is a survey of the local grey seal population in the entire Lower Saxony and Hamburg Wadden Sea during the birthing season (November-December) and at the time of the fur change (March-April).
On five trilaterally coordinated dates (three during the birthing season; two during the fur-change period), airborne surveys will be conducted with a single-engine aircraft. During the aerial surveys of the tidal flats, a high-resolution SLR camera will be used to photograph the haul-outs. In order to determine the number of young born as well as the total population, the photos taken are subsequently analyzed on the computer.
Results:

Schop J., Abel C., Brasseur S., Galatius A., Jeß A., Meise K., Meyer J., van Neer A., Stejskal O., Siebert U., Teilmann J., Thøstesen C. B. (2022) Grey Seal Numbers in the Wadden Sea and on Helgoland in 2021-2022. Common Wadden Sea Secretariat, Wilhelmshaven, Germany.

https://www.waddensea-worldheritage.org/resources/2021-2022-grey-seal-report

Show Details
HELCOM biodiversity, litter, underwater noise and effective regional measures for the Baltic Sea "HELCOM BLUES"
HELCOM biodiversity, litter, underwater noise and effective regional measures for the Baltic Sea "HELCOM BLUES"
Project Investigators: Prof. Prof. h. c. Dr. Ursula Siebert; Dr. Anita Gilles; Dr. Dominik Nachtsheim
Duration: January 2021 until January 2022
Funding: EU, 8.320 EUR
Project Details:
The overall aim of the HELCOM BLUES project is to support regional capacity, coordination and cooperation with regards to developing effective measures to secure good status of the marine environment. This includes provisioning, and making available, necessary knowledge to advance the development and implementation of joint measures addressing common pressures, as well as to provide concrete support to the decision-making process within the Baltic Sea region.
The task carried out by TiHo focuses on highly mobile and under-reported groups (here: cetaceans), and considers several aspects identified in recent HELCOM review processes to be knowledge/assessment gaps and aspects of high regional priority. The harbour porpoise can be categorised as both a highly mobile and an under-reported species in the Baltic Sea region. At present, there are no functional regional HELCOM indicator(s) to assess status for abundance or distribution, which are two of the primary Marine Strategy Framework Directive criteria under MSFD D1. This clear gap was identified as a high priority for the HELCOM region. This task will provide support for the HELCOM indicator team and focus on improving methods and operational assessments of harbour porpoise abundance by HOLAS III, and on harmonising methods of assessment with other EU regions (i.e. OSPAR and HELCOM). The main aspects addressed by TiHo are:
1) Establishment of a harmonised approach to indicator development for harbour porpoises between HELCOM and OSPAR (of particular relevance to shared marine areas);
2) Assessing trend in abundance for assessment of the Belt Sea population;
Results:

final report of the EU project "HELCOM BLUES"

https://blues.helcom.fi/wp-content/uploads/2023/09/HELCOM-BLUES_Activity_2.4-Harbour-porpoise-Main-report.pdf

Cooperation Partners:

Project coordinator

Helsinki Commission (HELCOM), Finland

Partners

Kiel Institute for the World Economy (IfW), Germany

University of Hamburg, Germany

Natural Resources Institute Finland (LUKE), Finland

Finnish Environment Institute (SYKE), Finland

Swedish University of Agricultural Sciences, Department of Aquatic Resources (SLU Aqua), Sweden

Stockholm University (SU), Sweden

Swedish Meteorological and Hydrological Institute (SMHI), Sweden

Swedish Agency for Marine and Water Management (SwAM), Sweden

Tallinn University of Technology (TalTech), Estonia

University of Tartu (UT), Estonia

Center for Environmental Policy (AAPC), Lithuania

Latvian Institute of Aquatic Ecology, Latvia

Show Details
Tourismus HUB; coordination and preparation on Seals - roles & functions as attractions for sustainable tourism in the Wadden Sea UNESCO World Heritage Site
Tourismus HUB; coordination and preparation on Seals - roles & functions as attractions for sustainable tourism in the Wadden Sea UNESCO World Heritage Site
Project Investigators: Prof. Prof. h. c. Dr. Ursula Siebert
Duration: Novemer 2021 until Novemer 2022
Funding: Common Wadden Sea Secretariat, 21.010 EUR
Project Details:
Harbor seals (Phoca vitulina) and grey seals (Halichoerus grypus) are the largest animals found in the Wadden Sea in Denmark, Germany and the Netherlands. Since the seals were placed under the protection of the Trilateral Wadden Sea Agreement and especially since the establishment of the Wadden Sea National Parks in Lower Saxony, Hamburg and Schleswig-Holstein, the severely depleted populations of seals and grey seals have been able to recover. The unique value of the marine mammals' habitat was confirmed in 2009 when the Wadden Sea was designated a UNESCO World Heritage Site. Seals and grey seals are "charismatic species" and therefore play an important role for recreation and tourism. This is also true for the Wadden Sea National Parks, where marine mammals are popular and serve as a tourist marketing tool.
The marine mammals are promoted as a tourist attraction in various places in the Wadden Sea, especially through organised seal watching trips. They thus represent an important
ecosystem service contributing to value generation for local economies.
These human-wildlife relationships are not without conflict: for example, the overlap of the high tourist season with the seals' whelping and nursing season from mid-June onwards is problematic. While observation cruises carried out by established shipping companies adhere to standards such as minimum distances to the seal banks and navigating at an adapted speed, private pleasure boats, wind and kite surfers are much more difficult to control. At the same time, less national park-specific tourism offers with event character have also increased in recent years. It is possible that this trend will continue due to the increased
domestic tourism demand observed during the Corona crisis. The effects of these different forms of tourism in the Wadden Sea on the stress levels and behaviour of marine mammals have not yet been sufficiently researched. Therefore, these questions will be investigated from an international and multidisciplinary perspective.
Information on behaviour can be obtained through observations and telemetry, and existing data will be analysed in this regard.
On the other hand, the importance of marine mammals for tourism will be investigated from a tourism perspective. The aim of the project is to present a scientifically sound framework that takes into account both the interests of wildlife and nature conservation in terms of minimising disturbance, and at the same time the needs of the tourism sector and the local economy in terms of business in terms of enhancing tourist attractions and developing attractive wildlife and nature experiences.
Cooperation Partners:

Prof. Dr. Julius Arnegger, International Tourism Management, DITF - German Institute for Tourism Research, West Coast University of Applied Sciences, 25746 Heide, Germany

Show Details
Investigations of pollutants and hearing damage in harbour porpoises from the Schleswig-Holstein North Sea and Baltic Sea
Untersuchungen von Schadstoffbelastungen und Gehörschädigungen von Schweinswalen aus der schleswig-holsteinischen Nord- und Ostsee
Project Investigators: Prof. Prof. h. c. Dr. Ursula Siebert; Maria Morell, PhD
Duration: July 2021 until February 2022
Funding: MELUND, 56.077 EUR
Project Details:
Research on marine mammals started in Büsum after the first seal mortality in 1988/89. The aim of the scientists is to study the biology and ecology of marine mammals and to assess the impact of humans on the animals, their health and their population. The scientific focus is on studies of health (exposure to pollutants, underwater noise, stress, immune system, infectious diseases, etc.) as well as behaviour, habitat use, population densities and impacts of anthropogenic interventions. Among other lines of research, the scientists are currently investigating the effects of underwater noise (e.g. from explosions, offshore wind turbines, shipping) on the behaviour and health of seals and harbour porpoises, chemical pollution and waste, disturbances and fishing on marine mammals. The stranding network ensures that whales and seals found on the coasts of Schleswig-Holstein can be reported, recovered and necropsied. The state of health is determined by means of further histological, microbiological and parasitological examinations. In this project, the tissues of porpoises found dead in the North Sea and the Baltic Sea will be examined for specific pollutants and the auditory apparatus will be analysed.
The following pollutants will be investigated in the liver and fat of harbour porpoises from waters in Schleswig-Holstein: polychlorinated biphenyls (PCBs) and derivatives, dichloro-diphenyl-trichloroethane (DDT), polybrominated diphenyl ethers (PBDEs) and mercury (Hg). The results of the toxicological investigation will be combined with the data on health status from the autopsies and an ecotoxicological assessment will be made. The results will be used for the development of further investigations for the various agreements, such as HELCOM, OSPAR, MSRL, and development of indicators.
For investigations of the auditory apparatus, dead harbour porpoises recovered within the framework of the small cetacean monitoring programme of the Land of Schleswig-Holstein should be collected immediately after reporting in order to remove and preserve the ears as fresh as possible for the investigation. In particular, harbour porpoises found dead after blasting and other impulse sound events as well as by-catches and live strandings shall be included. High-resolution computed tomography scans of the ear bones will be performed as well as confocal microscopic and histological examinations.
The studies on the auditory apparatus of harbour porpoises carried out in this project will be considered in the context of ongoing or completed studies at ITAW with similar questions. The results of this project will be used to assess whether changes in various structures of the auditory pathways may have been caused by exposure of harbour porpoises to explosions or other impulsive sound events.
Results:

Bericht an das Ministerium für Energiewende, Klimaschutz, Umwelt und Natur des Landes Schleswig-Holstein

https://www.schleswig-holstein.de/DE/fachinhalte/A/artenschutz/Downloads/untersuchungSchweinswale2021.pdf?__blob=publicationFile&v=1

Show Details
Determination of the sound level in nursery compartments for pigs with regard to animal welfare and human health and safety
Ermittlung des Schallpegels in der Ferkelaufzucht mit Bezug zu Tier- und Arbeitsschutz
Project Investigators: Kroll, Laura; Fels, Michaela; Kemper, Nicole
Duration: May 2021 until Novemer 2022
Funding: QS-Wissenschaftsfonds, 30.000 EUR
Project Details:
The aim of this study is to determine the sound level in pigs' nursery compartments and to detect the effects of animal behaviour and barn technology on the sound level.
In addition, occupational safety will be considered in the study by identifying particular sound events to which both, animals and humans are exposed, and quantifying them with regard to the sound pressure level. The aim is to generate representative data on noise pollution in today's piglet rearing in Germany, to determine the origin of noise pollution and - if necessary - to identify potential for improvement in terms of animal welfare and occupational safety.
Results:

https://doi.org/10.1016/j.livsci.2024.105410

Show Details
6FT21 COFONI Fast-Track - SARS-CoV-2 antigenic cartography for future COVID-19 vaccine composition
6FT21 COFONI Fast-Track - SARS-CoV-2-Antigenkartographie für die zukünftige COVID-19-Impfstoffzusammensetzung
Project Investigators: Prof. Osterhaus; Dr. Steffen
Duration: September 2021 until May 2022
Funding: MWK über UMG Göttingen, 41.000 EUR
Project Details:
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus Type 2) is the causative agent of COVID-19. The course of the COVID-19 pandemic so far has emphatically shown that a coordinated bundling of interdisciplinary and complementary expertise is necessary in order to decode the diverse aspects of the biology, pathology and epidemiology of SARS-CoV-2 and to use the knowledge gained clinically for the treatment of patients as well as for modeling the course of infection in the population. In order to be able to provide and implement such a holistic approach, the federal state of Lower Saxony offers ideal conditions with its internationally renowned science locations. We are therefore applying for financial support for collaborative research to set up a COVID-19 research network in the state of Lower Saxony (COFONI).
Show Details
10FT21 COFONI Fast-Treck - Validation of FDA-approved small molecule kinase inhibitor (SMKI) candidates as SARS-CoV-2 therapeutics in a human ex vivo system.
10FT21 COFONI Fast-Treck - Validierung von der FDA zugelassenen Kandidaten für kleinmolekulare Kinase-Inhibitoren (SMKI) als SARS-CoV-2-Therapeutika in einem menschlichen Ex-vivo-System.
Project Investigators: Prof. Guus Rimmelzwaan; Husni Elbahesh, PhD
Duration: September 2021 until August 2022
Funding: MWK über UMG Göttingen, 34.750 EUR
Project Details:
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus Type 2) is the causative agent of COVID-19. The course of the COVID-19 pandemic so far has emphatically shown that a coordinated bundling of interdisciplinary and complementary expertise is necessary in order to decode the diverse aspects of the biology, pathology and epidemiology of SARS-CoV-2 and to use the knowledge gained clinically for the treatment of patients as well as for modeling the course of infection in the population. In order to be able to provide and implement such a holistic approach, the federal state of Lower Saxony offers ideal conditions with its internationally renowned science locations. We are therefore applying for financial support for collaborative research to set up a COVID-19 research network in the state of Lower Saxony (COFONI).
Show Details
5FT21 COFONI Fast-Track - Detection Dogs as firstline screening method for SARS-CoV-2 Infection
5FT21 COFONI Fast-Track - Spürhunde als Erstlinien-Screening-Methode für eine SARS-CoV-2-Infektion
Project Investigators: Dr. Schulz
Duration: August 2021 until February 2022
Funding: MWK über UMG Göttingen, 29.847 EUR
Project Details:
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus Type 2) is the causative agent of COVID-19. The course of the COVID-19 pandemic so far has emphatically shown that a coordinated bundling of interdisciplinary and complementary expertise is necessary in order to decode the diverse aspects of the biology, pathology and epidemiology of SARS-CoV-2 and to use the knowledge gained clinically for the treatment of patients as well as for modeling the course of infection in the population. In order to be able to provide and implement such a holistic approach, the federal state of Lower Saxony offers ideal conditions with its internationally renowned science locations. We are therefore applying for financial support for collaborative research to set up a COVID-19 research network in the state of Lower Saxony (COFONI).
Show Details
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