Research

Analysis of the impact of a canine distemper virus infection on canine histiocytic sarcoma cells with special emphasis on tumor microenvironment in vitro and in vivo

Untersuchungen über den Einfluss einer kaninen Staupevirusinfektion auf kanine histiozytäre Sarkomzellen unter besonderer Berücksichtigung des Tumormikromilieus in vitro und in vivo

Project Investigators: Dr. C. Puff; Prof. Dr. W. Baumgärtner, PhD; Mara S. Lombardo; Thanaporn Asawapattanakul

Duration: Beginning 2011 until 2028

Show Details

Occurrence of ticks and tick-borne pathogens

Vorkommen von Zecken und zeckenübertragenen Pathogenen

Project Investigators: Prof. Dr. C. Strube, PhD; Dr. A. Springer

Duration: Beginning 2010 until Mid 2028

Funding: EU-Interreg, Bavarian Nordic, 270.000 EUR

Project Details:
Ticks transmit various human and animal pathogens. With regard to pathogens, the vector function of ticks for the causative agent of Lyme borreliosis (Borrelia burgdorferi sensu lato complex), human and animal granulocytic anaplasmosis and tick-borne encephalitis (TBE virus) is of particular importance. Studies on the abundance and distribution of ticks and their pathogens are therefore essential for assessing the One Health risk. Regarding tick-transmitted pathogens, this project collects data not only for Germany but also at the international level.

Results:

Rapp, J., Springer, A., Strube, C. (2024) Ixodes ricinus ticks survive flooding.  Ticks and Tick-Borne Diseases 15, 102417

Springer, A., Jordan, D., Höltershinken, M., Barutzki, D., Strube, C. (2024) Endemisation and management of Babesia divergens on a beef production farm. Current Research in Parasitology & Vector-Borne Diseases 6, 100188

Springer, A., Lindau, A., Probst, J., Fachet, K., Schäfer, I., Dobler, G., Mackenstedt, U., Strube, C. (2024) Germany-wide Citizen Science study reveals spread of Babesia canis-infected Dermacentor reticulatus ticks by dogs travelling within the country. Current Research in Parasitology & Vector-Borne Diseases 6, 100d187

Probst, J., Springer, A., Fingerle, V., Strube, C. (2024) Frequency of Anaplasma phagocytophilum, Borrelia spp. and coinfections in Ixodes ricinus ticks collected from dogs and cats in Germany. Parasites & Vectors 17, 87

Probst, J., Springer, A., Topp, A.-K., Bröker, M., Williams, H., Dautel, H., Kahl, O., Strube, C. (2023) Winter activity of questing ticks (Ixodes ricinus and Dermacentor reticulatus) in Germany − Evidence from quasi-natural tick plots, field studies and a tick submission study.  Ticks and Tick-Borne Diseases 14, 102225

Cooperation Partners:

Dr. O. Kahl, tick-radar GmbH

Prof. Dr. U. Mackenstedt, Universität Hohenheim

Dr. V. Fingerle, Nationales Referenzzentrum für Borrelien, Oberschleißheim

Prof. Dr. G. Dobler, Nationales Konsiliarlabor für FSME, München

Dr. L. Chitimia Dobler, Fraunhofer-Institut für Immunologie, Infektions- und Pandemieforschung

Show Details

Long-term monitoring of tick abundance and prevalence of Borrelia spp. and other pathogens in the city of Hannover, Germany

Langzeit-Monitoring der Zeckenabundanz und Befallshäufigkeit mit Borrelia spp. und anderen Pathogenen im Stadtgebiet Hannover

Project Investigators: Prof. Dr. C. Strube, PhD; Dr. A. Springer

Duration: Beginning 2005 until Beginning 2028

Project Details:
Ticks of the genus Ixodes transmit various human and animal pathogens. In this long-term project running since 2005, pathogen prevalence in ticks in the city of Hannover, Germany, is monitored to investigate potential effects of climate change. In addition to the infection status of the ticks, the tick density in the Hannover area will also be determined.

Results:

Glass, A., Springer, A., Raulf, M.-K., Fingerle, V. Strube, C. (2023) 15-year Borrelia prevalence and species distribution monitoring in Ixodes ricinus/inopinatus populations in the city of Hanover, Germany. Ticks and Tick-Borne Diseases 13, 102074

Glass, A., Springer, A., Strube, C. (2022) A 15-year monitoring of Rickettsiales (Anaplasma phagocytophilum and Rickettsia spp.) in questing ticks in the city of Hanover, Germany. Ticks and Tick-Borne Diseases 13, 101975

Hauck, D., Springer, A., Chitimia-Dobler, L., Strube, C. (2020) Two-year monitoring of tick abundance and influencing factors in an urban area (city of Hanover, Germany). Ticks and Tick-Borne Diseases 11, 101464

Blazejak, K., Raulf, M.-K., Janecek, E., Jordan, D., Fingerle, V., Strube, C. (2018) Shifts in Borrelia burgdorferi (s.l.) geno-species infections in Ixodes ricinus over a 10-year surveillance period in the city of Hanover (Germany) and Borrelia miyamotoi-specific Reverse Line Blot detection. Parasites & Vectors 11, 304

Blazejak, K., Janecek, E., Strube, C. (2017) A 10-year surveillance of Rickettsiales (Rickettsia spp. and Anaplasma phagocytophilum) in the city of Hanover, Germany, reveals Rickettsia spp. as emerging pathogens in ticks. Parasites & Vectors 10, 588

Cooperation Partners:

Dr. V. Fingerle, Nationales Referenzzentrum für Borrelien, Oberschleißheim

Show Details

INsect-based Sustainable Poultry feed for ImpRoved food safEty - INSPIRE

Erhöhung der Lebensmittelsicherheit der Geflügelfleischerzeugung durch Einsatz von Nebenströmen aus der Insektenlarvenproduktion in der Geflügelfütterung

Project Investigators: Prof. Dr. J. Hankel; Chiara Müller

Duration: April 2026 until March 2027

Show Details

Influence of replacing meat with the microalgae Spirulina spp. and Chlorella spp. on the physicochemical and microbiological properties of cooked sausage made from pork, beef and chicken meat

Einfluss des Ersatzes von Fleisch durch die Mikroalgen Spirulina spp. und Chlorella spp. auf die physikochemischen und mikrobiologischen Eigenschaften von Brühwurst aus Schweine-, Rind- und Hähnchenfleisch

Project Investigators: Prof. Dr. Carsten Krischek; Dr. Lisa Siekmann; Prof. Dr. Madeleine Plötz

Duration: January 2026 until December 2027

Show Details

Improving effectiveness through adapted formulations of phages and bacteriocins in minced meat products and other meat preparations

Verbesserung der Effektivität durch angepasste Formulierungen von Phagen und Bakteriozinen in Hackfleischprodukten und anderen Fleischzubereitungen

Project Investigators: Dr. Sophie Kittler; Dr. Oleksandra Berhilevych; Dr. Elisa Peh; Prof. Dr. Madeleine Plötz; Prof. Dr. Willem Wolk

Duration: February 2025 until January 2027

Show Details

Testing the effectiveness of alternatives to antibiotics in dog skin infections caused by Staphylococcus pseudintermedius

Wirksamkeitsüberprüfung von Alternativen zu Antibiotika bei Hautinfektionen des Hundes verursacht durch Staphylococcus pseudintermedius

Project Investigators: Jessica Meißner

Duration: October 2025 until September 2027

Show Details

Studies on interactions between otitis externa preparations and ear cleaners in dogs

Untersuchungen zu Wechselwirkungen von Otitis externa-Präparaten und Ohrreinigern beim Hund

Project Investigators: Jessica Meißner

Duration: July 2025 until June 2027

Show Details

Sperm selection without centrifugation - development of a microfluidic chip system for sperm selection from larger sample volumes

Spermienselektion ohne Zentrifugation - Entwicklung eines Mikrofluidic-Chip Systems zur Spermienselektion größerer Probenvolumina

Project Investigators: Harald Sieme; Harriette Oldenhof; Julius Goeke

Duration: April 2025 until March 2027

Show Details

Cosmic Radiation response in the simplest animal on Earth: Trichoplax, a new evolutionary animal model for Space Biology Research

Project Investigators: Bernd Schierwater

Duration: 2025 until 2027

Show Details

TiHo-Services

Information

Contact