Research

Funding: Stiftung Innovation in der Hochschullehre, 1.349.525 EUR

Project Details:
The FERVET project addresses the digital teaching and review of mandatory clinical-practical skills in veterinary medicine studies and pursues three aims:
1. the enrichment of face-to-face, hybrid and virtual teaching through the development of simulators, the provision of digital teaching material, the development of a Virtual Learning Lab, the expansion of video production and the implementation of video annotations.
2. the further development and evaluation of existing formative and summative e-examination formats
3. the anchoring of the innovative measures in the university structures

Funding: EU, 215.581 EUR

Project Details:
The project is carried out at DIL e.V., Quakenbrück.
The DIL leads the work package that focuses on optimising and up-scaling ultrasound (US). Firstly, an extensive literature review on microbial decontamination by US in food and model systems was conducted. It was found that manothermosonication (MTS), a technology that combines mild thermal treatment, elevated pressure, and sonication, is the most promising approach and a potential alternative to traditional thermal pasteurisation of liquid whole egg. Consequently, the DIL developed an MTS prototype that can be used for experimental work with Salmonella Enteritidis. The results showed that MTS can provide the same level of food safety as conventional pasteurisation but with a lower thermal load, suggesting potential food quality benefits confirmed by work on physico-chemical, functional, and protein properties. In addition, sustainability studies using the life cycle analysis (LCA) methodology revealed a lower energy demand in MTS pasteurisation. As a final part of the project, a computational fluid dynamics simulation will be performed to design industrial MTS treatments for continuous application.

Cooperation Partners:

External cooperation partners:

Wageningen University, L-Università ta' Malta,

University of Reading,

Elea Vertriebs- und Vermarktungsgesellschaft mbH,

Leibniz Institut für Plasmaforschung und Technologie e.V.,

Sociedade de Estudos de Analise Sensorial a Produtos Alimentares,

Stichting Wageningen Research,

Hyperbaric,

Arla Foods,

Unilever Research and Development Vlaardingen BV,

Koninklijke Euroma BV,

Société des Produits Nestlé S.A.

Funding: BMEL, ERA-NET, 117.043 EUR

Project Details:
The project is carried out on DIL e.V., Quakenbrück.
With CLIMAQUA an innovative process for the conversion and recycling of aquaculture side streams to feed based on A. platensis is created, which in turn can be used in aquaculture. The aim is to significantly reduce the high greenhouse gas emissions from aquaculture, especially for feed production, by integrating A. platensis into biomass / feed production. Geographical and site-specific features (temperature, length of daylight, etc.) are taken into account in order to obtain an almost completely digestible algae-based feed for salmon and catfish farming and thereby establish a circulatory system that is economically and ecologically sound. In addition, CLIMAQUA examines climate change-related aspects of aquaculture in two regions of the world: The use of innovative technologies in aquaculture is adapted to the climatic conditions and promotes the implementation of sustainable and local food systems.

Project Details:
Cognitive dysfunction is characteristic to the prodromal stages of Parkinson´s disease, and more generally to synucleinopathies. We test novel therapeutic options for cognitive dysfunction associated with alpha-synuclein pathology. We base our interest on microRNAs (miRNAs) which are small endogenous RNAs, and will test the hypotheses that specific miRNAs that are downregulated in PD brains are associated with cognitive dysfunction and, when delivered into the diseased brain, can form the basis for miRNA replacement therapy.

Cooperation Partners:

Prof. Eran Hornstein (Weizmann Institute, Israel); Prof. Achim Aigner (Klinische Pharmakologie, Universität Leipzig)

Funding: Interdisciplinary Center for Clinical Research (IZKF) of the University Hospital Erlangen

Project Details:
To investigate the impact of chronic colitis on the behavioral phenotype of mice expressing human α-synuclein under the Thy1-promoter(Thy1-αSyn mice), a well-established mouse model for synucleinopathies.

Cooperation Partners:

Dr.med. Patrick Süß, Prof. Dr. Jürgen Winkler (Dept of Molecular Neurology, Universitätsklinikum Erlangen)

Funding: Stiftung Innovation in der Hochschullehre, 549.540 EUR

Project Details:
The aim of the SOUVER@N project is to promote sovereign digital teaching and learning. This includes
1) the sovereign, i.e. competent and learning goal-oriented use of digital tools on the part of teachers and students (digital literacy) as well as
2) the professional development of high-quality digitally enriched teaching/learning concepts and content, and
3) the digital sovereignty of the universities as institutions strengthened by the network.

Results:

https://www.souveraenes-digitales-lehren-und-lernen.de/home/

Cooperation Partners:

1) Universität Osnabrück

2) Carl von Ossietzky Universität Oldenburg

3) Leuphana Universität Lüneburg

4) Technische Universität Clausthal

5) Stiftung Universität Hildesheim

6) Universität Vechta

7) Medizinische Hochschule Hannover

8) ELAN e.V. (1. Förderphase August 201 - Juli 2024)

Project Details:
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Project Details:
Diagnostic imaging of the equine cervical and thoracic spine has become increasingly important in recent years. The focus is on radiographic examinations, but also nuclear medicine and computed tomography are commonly used to address various clinical questions.
This project deals with the clinical relevance of radiographic and nuclear scintigraphy findings of the thoracic spine in relation to back pain and rideability problems as well as the diagnostic value of computed tomography and computed tomographic myelography in horses with spinal ataxia.

Funding: MWK über Uni Göttingen, 732.193 EUR

Project Details:
Das SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-Type 2) ist der Erreger von COVID-19. Der bisherige Verlauf der COVID-19 Pandemie hat nachdrücklich gezeigt, dass eine koordinierte Bündelung von interdisziplinären und komplementären Expertisen notwendig ist, um die vielfältigen Aspekte der Biologie, der Pathologie und der Epidemiologie von SARS-CoV-2 zu entschlüsseln und die gewonnenen Erkenntnisse sowohl klinisch für die Behandlung von Patienteninnen und Patienten als auch für die Modellierung von Infektionsverläufen in der Bevölkerung einzusetzen. Um einen solch holistischen Ansatz leisten und umsetzen zu können, bietet das Bundesland Niedersachsen mit seinen international renommierten Wissenschaftsstandorten ideale Voraussetzungen. Das Forschungsnetzwerk COFONI arbeitet am Aufbau eines COVID-19 Forschungsnetzwerkes des Landes Niedersachsen (COFONI)um gebündelt Forschungsvorhaben zur Entwicklung neuer Strategien zur Bekämpfung von COVID-19 zu entwickeln. Hauptfokus der Technologieplattform Tiermodelle ist der Aufbau von Tiermodellen für COVID-19.

Project Details:
In this 5-year monitoring-study the density, diversity and community structure of Collembola and Mesostigmata of three different biotope types (oak-hornbeam-mixed forest, drainage ditch (edge), wet meadow) are investigated in the nature reserve Riddagshausen, a Flora-Fauna-Habitat (FFH) area characterized by a small scale mosaic of different habitat types like ponds, meadows, farmland and mixed forests. In each of the biotope types 10 sampling points spaced at least 20 m apart from each other were selected at random. Large spacing was done to avoid spatial autocorrelation, samples therefore were assumed to be independent.
Starting in March 2021 ten soil cores (diameter 5 cm) were taken at each of the biotope types (one soil core per sampling point). The cores were subdivided into two horizons (litter layer, 5 cm mineral soil). The soil cores were used to extract Collembola, Gamasida and soil macrofauna using a modified high gradient canister method (Macfadyen, 1961; Schauermann, 1982). Collembola and Mesostigmata were determined to species level.
Moreover, Collembola species were aggregated into three different functional groups according to their vertical distribution (epedaphic, hemiedaphic, and euedaphic). These groups differ in their dispersal ability and other attributes such reproduction, mobility, metabolic activity and feeding behaviour.
This sampling and identification pattern will be repeated every year (2021-2025) in early spring (March/April).
We expect changes in the soil fauna communities of the investigated biotope types due to strong differences in the amount of precipitation between the years.

Cooperation Partners:

1) Prof. Stefan Scheu, J.F. Blumenbach Institute of Zoology and Anthropology, University of Goettingen

2) Dr. Bernhard Klarner