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2235 results.
Hormonal castration in tom cats
Hormonelle Kastration beim Kater
Project Investigators: Goericke-Pesch, S.
Duration: June 2019 until May 2021
Funding: Industry (Veterinary pharmaceuticals/Vaccines), 550.000 EUR
Project Details:
confidential
Results:

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1274-9268

Show Details
Downregulation and recrudescence of spermatogenesis after use of a GnRH-agonist implant in male dogs
Downregulation und Wiederanlaufen der Spermatogenese nach Anwendung eines deslorelin-haltigen GnRH- Implantates beim Rüden
Project Investigators: Goericke-Pesch, Sandra; Stempel, Sabrina
Duration: End 2019 until Mid 2021
Project Details:
Ein koordiniertes Ein- und Abschalten vieler verschiedener Regulationsmechanismen ist bedeutend für den physiologischen Ablauf der Spermatogenese. Beim Rüden kann diese durch Verabreichung eines GnRH-Implantats mittels nachfolgender Downregulation unterbrochen werden. Nach Wirkungsende bzw. Implantatentfernung erfolgt wieder eine Aufregulation der endokrinen und germinativen Hodenfunktion.
Ziel ist es zum einen herauszufinden, wann die Downregulation vollständig erfolgt und der Rüde somit infertil ist. Zum anderen werden neue Ergebnisse zur Dauer des Wiederanlaufens der Spermatogenese nach Implantatentfernung erwartet, also wann erste Spermien im Ejakulat nachweisbar sind und wann vor allem normale Spermaparameter wieder erreicht werden und somit die Fertilität wiederhergestellt ist.
Für die Praxis ist es von großer Bedeutung, wann mit einer erfolgreichen Bedeckung gerechnet werden kann/muss, sowohl für Züchter, aber insbesondere auch für Besitzer von einem mit Deslorelin-Implantat behandelten Rüden, die Kontakt zu intakten Hündinnen haben.
Mit dem aus diesem Projekt resultierenden Wissen lassen sich unerwünschte Bedeckungen besser verhindern.
Results:

https://doi.org/10.3390/ani12182379

https://doi.org/10.3390/ani12192545

Show Details
Equine endometritis - evidence-based and anecdotal practices
Die Endometritistherapie bei der Stute - zwischen evidenzbasiert und anekdotisch
Project Investigators: Prof. Dr. Harald Sieme; Tierärztin Meike Kuhlmann; Dr. Martin Köhne, Dipl ECAR
Duration: March 2019 until September 2021
Project Details:
Ziel der Untersuchungen ist es, mittels eines Fragebogens, der deutschlandweit an Pferdepraktiker versendet werden soll, einen Überblick über das in der Praxis vorhandene Wissen über die Ätiologie, Diagnostik und Therapie zu erhalten. Durch eine Metaanalyse der vorhandenen Literatur sollen die bekannten Methoden der Endometritisdiagnostik und -therapie auf ihre wissenschaftlichen Grundlagen hin überprüft werden.
Die Studien werden in Hinblick auf ihr unterschiedliches Studiendesign untersucht und in verschiedene Evidenzstufen eingeteilt um ihre Vergleichbarkeit und Fundiertheit zu bewerten. Es ist also zu klären, ob die Endometritisdiagnostik und -therapie in Deutschland auf evidenzbasierten Studien beruht oder ob die Praktiker eher auf ihre Erfahrungen bzw. die Anekdoten von Kolleginnen und Kollegen vertrauen. Außerdem sollen neue Möglichkeiten zur Minimierung des Antibiotikaeinsatzes aufgezeigt werden.
Results:

doi: 10.3389/fvets.2020.00547. PMID: 32984410

Cooperation Partners:

Niedersächsisches Landgestüt Celle

Show Details
Reduction of antibiotics in preserved boar semen
Reduktion von Antibiotika in konserviertem Ebersperma
Project Investigators: Prof. Dr. Dagmar Waberski; Dr. Anne-Marie Luther
Duration: May 2019 until December 2021
Project Details:
Addition of antibiotics to semen extenders is required to control the growth of commensale bacteria in animal semen. Follwing the One Health concept and the DART strategy for reduction of antibiotics, alternative antimicrobial strategies in preserved boar semen are tested.
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Hypothermic preservation of boar semen: Screening of boar eligibility in an artifical insemination center
Hypotherme Konservierung von Ebersperma: Screening der Eignung von Ebern einer Besamungsstation
Project Investigators: Prof. Dr. Dagmar Waberski; Dr. Anne-Marie Luther
Duration: May 2019 until December 2021
Project Details:
Boar spermatozoa are sensitive to cooling and, therefore, commonly are preserved at 16°C for use in artificial insemination (AI). Recently, hypothermic semen preservation at 5°C was established to reduce the risk for bacterial growth and to stabilize transport conditions. The aim is to assess the eligibility of AI boars for hypothermic semen preservation using conventional spermatology.
Cooperation Partners:

Hochschule Osnabrück

GfS Ascheberg

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Development of Loop-mediated isothermal amplification (LAMP) -Assays for the fast detection of food-borne pathogens
Entwicklung von Loop-mediated isothermal amplification (LAMP) -Assays als schnelle Methode zum sofortigen Nachweis von Erregern bei Lebensmittelinfektionen und -intoxikationen
Project Investigators: PD Dr. Amir Abdulmawjood; Dr. André Becker; Antonia Kreitlow; Annemarie Busch
Duration: January 2019 until December 2021
Funding: Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr, 449.842 EUR
Project Details:
Im Bereich der Lebensmittelsicherheit ist eine genaue und schnelle Identifikation des ursächlichen Erregers mikrobieller Kontaminationen von Lebensmitteln aufgrund möglicher Lebensmittelinfektionen und -intoxikationen von besonderer Bedeutung. In dem o.g. Projekt werden deshalb auf Basis der sogenannten schleifen-vermittelten ("loop-mediated") Amplifikationsmethode Schnellnachweise für verschiedene bedeutende pathogene Keime (Bacillus cereus, Campylobacter jejuni, Campylobacter coli, Listeria monocytogenes, Salmonella und Staphylococcus aureus) entwickelt. Das LAMP-System funktioniert unter isothermalen Bedingungen, d.h. es werden keine Geräte mit zyklischer Amplifikation (PCR) benötigt. Die Detektion kann in einem auf etwa 65 °C erhitzen Wasserbad oder Heizblock erfolgen. Die Entwicklung und Validierung der Testsysteme wird mit Hilfe des tragbaren real-time Fluorometers Genie® II (Firma OptiGene) durchführt. Ziel des Projektes ist es, verlässliche und schnelle Nachweismethoden wichtiger Mikroorganismen aus verschiedenen Lebensmittelmatrizes zu entwickeln und zu etablieren, welche in der Routinediagnostik Anwendung finden sollen.
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Alternatively cured meat products - influences on technological properties and microbiological safety
Einfluss alternativer Pökelverfahren auf technologische, mikrobiologische und physikalische Parameter von Fleischwaren
Project Investigators: Dr. A. Becker; Björn Schopfer; PD Dr. Carsten Krischek; Prof. Dr. Corinna Kehrenberg, PhD; Prof. Dr. Madeleine Plötz
Duration: January 2019 until December 2021
Funding: Fritz-Ahrberg-Stiftung, 57.000 EUR
Project Details:
The production of meat-based food using nitrite curing salt has become a target of public criticism. After the WHO classified the consumption of processed meat products as "carcinogenic to humans (Group I)", food processors are searching for alternatives to nitrite usage. Besides uncured products, plant extracts as a natural source of nitrate can be used in the production process. It is stated that those products contain lower concentrations of harmful residual nitrite and might therefore be beneficial for human health. However, the question remains whether those "naturally-cured" products remain microbiologically stable and whether they are indeed healthier. Furthermore, those products have to be organoleptically comparable to products containing nitrite curing salt to meet consumers expectations. The present study is investigating the impact of different alternative curing methods of cooked sausages on product quality and food safety using two different vegetable extracts (mangold, beetroot). Aim is to gain knowledge about sensory, microbiologically and physicochemical parameters of alternatively cured meat products. The results can provide important information for food processors as well as for supervising authorities.
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DigiStep - Digitization steps of teaching content in veterinary studies at University of Veterinary Medicine Hannover, Foundation
DigiStep - Digitalisierungsschritte von Lehrinhalten im Tiermedizinstudium an der Stiftung Tierärztliche Hochschule Hannover
Project Investigators: Dr. Martina Buchholz; PD Dr. S. Aboling; Prof. Dr. Heike Pröhl; Prof. Dr. Klaus Jung; Dr. Beate Röll u.a.
Duration: January 2019 until December 2021
Funding: Niedersächsischen Ministerium für Wissenschaft und Kultur, 299.878 EUR
Project Details:
Das Projekt ist so konzipiert, dass digitale Medien in verschiedenen Kontexten angewendet werden. Neben Online-Lernmodulen und Fallbeispielen sollen Videomaterial und Vortrags- sowie Vorlesungsaufzeichnungen eingesetzt werden, so dass E-Learning-Konzepte wie Blended Learning und Inverted Classroom umsetzbar sind. Darüber hinaus werden mit dem Projekt die Zoologischen Übungen, bei denen Präparationen an eigens zu diesem Zwecke getöteten Tiere vorgenommen werden, umgestellt und dadurch die Anzahl von verwendeten Tieren erheblich reduziert. Durch die im Studium frühe Implementation der Digitalisierung der Lehre wird der Weg für weitere digitale Lehrformen im späteren Verlauf des Studiums und für die Weiterentwicklung des bestehenden Curriculums bereitet.
Results:

Liebig P, Pröhl H, Sudhaus-Jörn N, Hankel J, Visscher C, Jung K (2022) Interactive, browser-based graphics to visualize complex data in education of biomedical sciences for veterinary students. Medical Science Educator https://doi.org/10.1007/s40670-022-01613-x

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Quality parameters of pork and turkey meat after freezing and thawing as well as after further processing and packaging of the fresh and frozen-thawed meat
Qualitätsparameter von Schweine- und Putenfleisch nach Gefrieren und Auftauen sowie nach Verarbeitung und Verpackung des frischen bzw. gefrorenen Fleisches
Project Investigators: PD Dr. Carsten Krischek; Dr. Diana Seinige
Duration: January 2019 until October 2021
Funding: Drittmittelprojekt, gefördert durch die Fritz-Ahrberg-Stiftung., 65.000 EUR
Project Details:
Freezing is a frequently used method for preservation of food. This method is also regularly used in connection with the import of meat from third countries. For example, frozen pork is imported from Chile and frozen poultry meat from Brazil. Although the freezing of the meat has a positive effect on the microbiological properties, the sensory and physico-chemical properties of the meat after thawing can also be negatively affected, which also has an influence on the storage and further processing of the products. Various changes in meat caused by freezing have been presented in publications so far. However, studies that have investigated the use and processing of frozen and subsequently thawed meat for the production of meat products (e.g. raw fermented sausages) are rare. This also applies to meat, packed under a protective gas atmosphere, which was frozen before packing. Therefore, in the present study, pig and turkey meat will be stored for 3, 6, 9 and 12 months, frozen at -18°C and -80°C, and processed into raw sausages after thawing. Comparatively, the meat will be also stored in modified atmosphere packaging (MAP) after thawing. For an assessment of the meat quality, certain microbiological, physico-chemical (e.g. colour, TBARS) or sensory analyses are carried out before freezing, after thawing and during storage/ maturing of the modified atmosphere packaged meat or raw fermented sausages. Control samples, which are processed or packaged without prior freezing, are included in each test run. The aim of the study is to investigate the influence of a freezing treatment of pork and turkey meat on the processing and storage properties of the thawed meat.
Results:

Teuteberg V., I.-K. Kluth, M. Plötz, C. Krischek* (2021):

Effects of duration and temperature of frozen storage on the quality and food safety characteristics of pork after thawing and after storage under modified atmosphere.

Meat Science, 108419, https://www.sciencedirect.com/science/article/abs/pii/S0309174020308512?via%3Dihub

 

Kluth, I.-K., V. Teuteberg, M. Plötz, C. Krischek* (2021):

Effects of freezing temperatures and storage times on the quality and safety of raw turkey meat and sausage products.

Poultry Science, 100, 101305, https://www.sciencedirect.com/science/article/pii/S0032579121003394?via%3Dihub

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Development and validation of a metagenome sequencing method for the detection of foodborne pathogens in drinking water
Entwicklung und Validierung eines Metagenom-Sequenzierungsverfahrens zum Nachweis von Lebensmittelinfektionserregern im Trinkwasser
Project Investigators: Prof. Dr. Corinna Kehrenberg; Prof. Dr. Madeleine Plötz; Dr. Diana Seinige; PD Dr. Carsten Krischek
Duration: October 2019 until October 2021
Funding: Drittmittelprojekt, gefördert durch das Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr., 272.949 EUR
Project Details:
Many microbial pathogens are transmitted via contaminated drinking water and cause severe diseases in humans. Therefore, it is necessary that drinking water is constantly monitored and microbial contamination is excluded. Compliance with limit values of the "Trinkwasserverordnung" is mandatory. However, monitoring is usually limited to the detection of indicator organisms that indicate faecal contamination of the water and are intended to predict the presence of pathogenic microorganisms. Nevertheless, outbreaks of diseases caused by contaminated drinking water, in which no indicator bacteria have been detected during analysis, have been frequently reported. Drinking water may also contain microorganisms that could not be detected during routine diagnostics. The development of a new method that comprehensively examines microbial diversity and the occurrence of pathogenic microorganisms from drinking water samples could set new standards for drinking water testing in the future. "Next Generation Sequencing" (NGS) is a very promising method for this. The aim of the project is therefore to carry out a parallel analysis of large quantities of DNA or RNA sequences by metagenome sequencing and to record the microbial diversity of water samples. Initial approaches using NGS technologies for this purpose have been described in the literature. Nevertheless, the isolation and concentration of microorganisms from water samples must first be optimised. Protocols, methods and bioinformatic pipelines must also be adapted to overcome the difficulties of detecting pathogenic microorganisms in drinking water. The protocols required for this will be developed in the project. Subsequently, the procedure will be validated against the methods described by the "Trinkwasserverordnung" or comparable reference methods. The determination of the analytical as well as the diagnostic sensitivity and specificity is the main focus of this research project. Furthermore, the methodology will be developed and established for different water samples (e.g. drinking water, surface water) and tested for its practicability with the help of field samples.
Show Details
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