Vorlesungsverzeichnis

obligatory for 1st year students

Beineke, Claus/Rhein, Ponimaskin, Viejo-Borbolla

Mon 05.05.25 - Fri 09.05.25, 09:00 - 17:00

Introduction to basic techniques in molecular biology (PCR, protein interaction, in situ hybridization etc.). It is the aim of this course to give a practically orientated insight to molecular techniques and their applications in neuroscience. Detailed descriptions and protocols will be handed out.
You have to choose one of the labs for the practical part.

Kästner, Schütter, Neudeck, Rupp, Wittenberg-Voges

Mon 14.04.25, 08:00 - 12:00

Special anaesthesia cases in cats, dogs and horses

Nessler, Meyerhoff, Lemke, Reeh, Watanangura, Jeroncic, Putzer, Riese, Tipold, Volk

Mon 28.04.25, 10:00 - 12:00

Special examinations of neurological cases.

Gernert, Meißner, Oltmanns, Richter Assêncio, Käufer, Joseph, Feja, Kotzur, Ebert, Kunzmann, Rundfeldt and colleagues

Wed 23.04.25, 14:00 - 16:00

Students are trained in experimental animal pharmacology, in vitro models and computer simulations, covering a wide spectrum of topics. About 50% of the course is dedicated to neuropharmacology, including topics such as anaesthesiology and behavioural pharmacology. At the beginning of the course there is introduction into the basics of research planning and data analysis, animal welfare and biometrics.

Volk, Nessler, Meyerhoff, Riese

Thu 24.04.25, 17:00 - 18:00 (preliminary meeting)

Case presentation and discussion of clinical and neuroimaging.

Perner

Tue 03.06.25 - Tue 10.06.25, 16:00 - 17:30

This lecture will explore the latest discoveries in the field of peripheral neuro-immune interactions, with a particular focus on the role of autonomic and sensory neurons in maintaining tissue homeostasis and orchestrating host defense.

We will discuss how neurons can directly communicate with and influence immune cells, shaping local immune responses. Key recent publications will be highlighted to provide an up-to-date overview of the most significant findings in this rapidly evolving field.

Ding and colleagues

Mon 28.04.25 - Mon 07.07.25, 09:30 - 11:00

This seminar will give an overview about the modern neuroimaging tools used to observe physiological/pathological changes in human central nervous system in vivo, such as the basics of MRI, the diffusion tensor imaging, the functional MRI, as well as the MR spectroscopy. Special CNS diseases caused by genetic defects or other noxa will also be shortly introduced.

1. MR basics, relaxation time measurement, DTI, Spectroscopy (Prof. Dr. X. Ding) 28.04.2025
2. Maturation of the brain (Prof. Dr. X. Ding) 05.05.2025
3. Clinical neuroanatomy (Priv.-Doz. Dr. A. Giesemann) 12.05.2025
4. Ischemic lesions in brain (Dr. F. Donnerstag) 19.05.2025
5. CNS -Tumor diagnostics (Priv.-Doz. Dr. P. Raab) 26.05.2025
6. Diagnosis of neuroinflammation and infection (Dr. K. Döring) 02.06.2025
7. Imaging of the Cranial Nerves (Priv.-Doz. Dr. A. Giesemann) 16.06.2025
8. Anatomy and pathology of cerebral vessels (Dr. O. Abu-Fares) 23.06.2025
9. Endovascular treatment of ischemic and hemorrhagic stroke (Priv.-Doz. Dr. G. Baltsavias) 30.06.2025
10. Further neuroradiological methods (Priv.-Doz. Dr. E. Bültmann) 07.07.2025

Krauss, Haghikia, Richter Assêncio, Schwabe

Wed 11.06.25 - Thu 12.06.25, 09:00 - 17:00

Day 1:
On the first day we will give an overview about the pathophysiology and symptoms of Parkinson?s Disease (PD), animal models for this condition and therapeutic approaches. In particular, the following topics will be addressed:
? clinical pathophysiology and symptoms of PD and pharmacological treatment of this condition (Prof. Petri, PD Höllerhage)
? basal ganglia function and animal models of PD (Prof. Schwabe, PD Alam)
? current pipeline of disease-modifying therapeutics (Prof. Richter Assêncio)
? neurosurgical approaches (ablative methods, deep brain stimulation) for the treatment of PD (Prof. Krauss)
Day 2:
The next day students will be divided in groups of 3?4 participants and trained in one specific method of the 6-hydroxydopamine (6-OHDA) PD model of the rat. In the afternoon each group will present their experience and data to the other groups. In particular, the following aspects will be addressed:
? stereotactic injection of 6-OHDA into the nigrostriatal system of the anaesthesized rat (Prof. Schwabe, PD Alam)
? immunohistological evaluation of the 6-OHDA lesion (Prof. Schwabe, PD Alam)
? immunohistological evaluation of the 6-OHDA lesion (Prof. Schwabe, PD Alam)
? behavioral and pharmacological evaluation of the 6-OHDA induced lesion (Prof. Schwabe, PD Alam)
? assessment of neuroprotective drug effects in vitro and in vivo (Prof. Richter Assêncio)
Day 3:
? Live surgery: a limited number of six students will be given the opportunity to attend surgery for deep brain stimulation in the subthalamic nucleus with patients of the Clinic for Neurosurgery (Prof. Krauss)
? Clinical examination and treatment of PD patients in the PD outpatient clinic of the Clinic for Neurology (Prof. Petri, PD Höllerhage).

Selected neurometabolic disorders and neurological development during childhood

Das, Hartmann

To be announced

In this seminar we will give an overview regarding diagnosis of inborn errors of metabolism and shall talk about some inborn errors of metabolism with neurological symptoms. We will deal with the biochemical basis/pathogenesis, clinical symptoms and therapeutic approaches of selected diseases in detail.
One seminar shall focus on the development of brain and psychomotor function during childhood.

Esser, Schmidt

Mon 26.05.25 - Fri 13.06.25, 09:00 - 17:00

In our seminar students present and discuss (together with us) recent literature from the field of neuro- and sensory biology with special reference to hearing, vision and multimodal orientation.