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2104 results.
Monitoring and control of pasture-borne helminthoses in ruminants
Monitoring und Bekämpfung von Weide-assoziierten Helminthosen bei Wiederkäuern
Project Investigators: Prof. Dr. C. Strube, PhD
Duration: Beginning 2016 until Mid 2028
Project Details:
Helminth infections influence animal health and thus also production parameters in ruminants. In the course of this project, epidemiological investigations and modelling will provide new insights into the distribution and infection dynamics of lungworms, gastrointestinal worms and liver fluke. At the same time, the influence of these parasitoses on production parameters will be determined and innovative control strategies evaluated.
Results:

Teschner, V., Zablotski, Y., Knubben-Schweizer, G., Bootz, F., Strube, C., Wenzel, C. (2025) Impact of the rumen fluke Calicophoron daubneyi on milk production parameters, β-hydroxybutyrate, fertility and feces consistency in southern German dairy cows. Veterinary Parasitology: Regional Studies and Reports 58, 101200

 

Leinmueller, M., Adler, F., Campe, A., Knubben-Schweizer, G., Hoedemaker, M., Strube, C., Springer, A., Oehm, A.W. (2024) Animal health as a function of farmer personality and attitude: Using the HEXACO model of personality structure to predict farm-level seropositivity for Fasciola hepatica and Ostertagia ostertagi in dairy cows. Frontiers in Veterinary Science 11, 1434612

 

Oehm, A.W., Leinmueller, M., Zablotski, Y., Campe, A., Hoedemaker, M., Springer, A., Jordan, D., Strube, C., Knubben-Schweizer, G. (2023) Multinomial logistic regression based on neural networks reveals inherent differences among dairy farms depending on the differential exposure to Fasciola hepatica and Ostertagia ostertagi. International Journal for Parasitology 53, 687-697

 

Vande Velde, F., Hektoen, L., Phythian, C.J., Rinaldi, L., Bosco, A., Hinney, B., Gehringer, M., Strube, C., May, K., Knubben-Schweizer, G., Martins, O.M.D., Mateus, T.L., Simion, V.E., Charlier, J., Bartley, D.J., Claerebout, E. (2023) Understanding the uptake of diagnostics for sustainable gastrointestinal nematode control by European dairy cattle farmers: a multi-country cross-sectional study. Parasite 30, 4

 

Vanhecke, M., Charlier, J., Hamdi, R., Duchene, F., Strube, C., Claerebout, E. (2022) Associations between Dictyocaulus viviparus bulk tank milk seropositivity correlated with meteorological variables. International Journal for Parasitology 52, 659-665

Cooperation Partners:

Prof. Dr. G. Knubben-Schweizer, Ludwig-Maximilians-Universität München

Prof. Dr. Edwin Claerebout, Ghent University

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Epidemiology of parasites and development or evaluation of diagnostic anf control tools in livestock and companion animals
Epidemiologie von Parasiten und Entwicklung beziehungsweise Evaluierung von Diagnostika und Bekämpfungsoptionen bei Haus- und Heimtieren
Project Investigators: Prof. Dr. C. Strube, PhD
Duration: Beginning 2012 until Mid 2028
Project Details:
Monitoring the epidemiology and prevalence of parasite infections in livestock and companion animals will contribute to a better knowledge of parasite distribution and improved control strategies. Furthermore, new diagnostics will be developed or existing ones improved.
Results:

Rüster, V., Lückemann, A.K., Wittmann, M., Strube, C., Bartels, T. (2023) Successful long-term control of poultry red mite (Dermanyssus gallinae) infestations in floor-kept laying hens via integrated pest management - a case report. Parasitology Research 122, 2549-2555

 

Rüster, V., Werner, H., Wieneke, S., Avramidis, G., Ten Bosch, L., Krause, E.T., Strube, C., Bartels, T. (2022) Short-time cold atmospheric pressure plasma exposition can kill all life stages of the poultry red mite, Dermanyssus gallinae, under laboratory conditions. Experimental and Applied Acarology 88, 139-152

 

Vismarra, A., Schnyder, M., Strube, C., Kramer, L. Colombo, L., Genchi, M. (2023) Diagnostic challenges for Aelurostrongylus abstrusus infection in cats from endemic areas in Italy. Parasites & Vectors 16, 187

 

Hauck, D., Raue, K., Blazejak, K., Hannah, R.M., Elsmore, D.A., Pantchev, N., Strube, C. (2023) Evaluation of a commercial coproantigen immunoassay for the detection of Toxocara cati and Ancylostoma tubaeforme in cats and Uncinaria stenocephala in dogs. Parasitology Research 122, 185-194

 

Waindok, P. Raulf, M.-K., Strube, C. (2022) Potentials and challenges in the isolation and detection ascarid egg in complex environmental matrices. Food and Waterborne Parasitology 28, e00174

Cooperation Partners:

Prof. Dr. M. Schnyder, Universität Zürich, Schweiz

Prof. Dr. D. Traversa, Universität Teramo, Italien

Show Details
Parasite occurence and diagnostics in wildlife
Parasitenvorkommen und Diagnostika bei Wildtieren
Project Investigators: Prof. Dr. C. Strube, PhD; Prof. Prof. h. c. Dr. U. Siebert
Duration: Beginning 2012 until Mid 2028
Project Details:
Surveys on the epidemiology or prevalence of helminth infections in wildlife will contribute to a better knowledge of parasite distribution and help implementing prevention strategies in terms of the One Health concept. Furthermore, the evaluation of new diagnostic tools will improve health monitoring in wildlife.
Results:

Bisterfeld, K., Raulf, M.-K., Waindok, P., Springer, A., Lang, J., Lierz, M., Siebert, U., Strube, C. (2022) Endoparasites of peritoneal organs and skeletal muscles of the European wildcat (Felis silvestris) in Germany. Parasite & Vectors 17, 473

 

Schütte, K., Springer, A., Brandes, F., Reuschel, M., Fehr, M., Strube, C. (2024) Ectoparasites of European hedgehogs (Erinaceus europaeus) in Germany and their health impact. Parasites & Vectors 17, 2

 

Rehbein, S., Jůnková Vymyslická, P., Peterka, T., Strube, C., Visser, M., Mayr, S., Lackerschmid, J. (2024) Calicophoron daubneyi (Paramphistomidae) in deer of the ?umava National Park, Czech Republic - Consequence of prevalent rumen fluke infection in cattle. Veterinary Parasitology: Regional Studies and Reports 50, 101012

 

Bisterfeld, K., Raulf, M.-K., Waindok, P., Springer, A., Lang, J., Lierz, M., Siebert, U., Strube, C. (2022) Cardio-pulmonary parasites of the European wildcat (Felis silvestris) in Germany. Parasite & Vectors 15, 452

 

Waindok, P., Raue, K., Grilo, M., Siebert, U., Strube, C. (2021) Predators in northern Germany are reservoirs for parasites of One Health concern. Parasitology Research 120, 4229-4239

Show Details
Analysis of the impact of a canine distemper virus infection on canine histiocytic sarcoma cells with special emphasis on tumor microenvironment in vitro and in vivo
Untersuchungen über den Einfluss einer kaninen Staupevirusinfektion auf kanine histiozytäre Sarkomzellen unter besonderer Berücksichtigung des Tumormikromilieus in vitro und in vivo
Project Investigators: Dr. C. Puff; Prof. Dr. W. Baumgärtner, PhD; Mara S. Lombardo; Thanaporn Asawapattanakul
Duration: Beginning 2011 until 2028
Project Details:
Das Tumormikromilieu stellt einen essentiellen Faktor sowohl beim Tumorwachstum als auch der Tumortherapie dar. Eine Komponente des Tumormikromilieus repräsentiert die Gefäßversorgung der Neoplasien, da Tumoren ohne vaskulären Anschluss ein limitiertes Größenwachstum bis zu einer kritischen Größe aufweisen, über die hinaus eine Versorgung der Zellen über Diffusion nicht mehr möglich ist. Des Weiteren weist das Tumormikromilieu infiltrierende Entzündungszellen auf, die sowohl wachstumsfördernde als auch -hemmende Effekte entfalten können. Das Tumormikromilieu stellt daher einen wesentlichen Angriffspunkt für neue therapeutische Interventionen dar. Histiozytäre Sarkome sind maligne Tumoren, die sowohl beim Hund als auch beim Menschen mit einer schlechten Prognose einhergehen und für die effektive Therapien oft nicht verfügbar sind. Daher stellt die virale Onkolyse einen faszinierenden Ansatzpunkt für die Erweiterung des Therapiespektrums dieser Neoplasie dar. Im vorliegenden Projekt soll der Einfluss einer kaninen Staupevirusinfektion auf kanine histiozytäre Sarkomzellen unter standardisierten in vitro Bedingungen als auch in einem murinen Xenotransplantationsmodell detailliert analysiert werden.
Show Details
Occurrence of ticks and tick-borne pathogens
Vorkommen von Zecken und zeckenübertragenen Pathogenen
Project Investigators: Prof. Dr. C. Strube, PhD; Dr. A. Springer
Duration: Beginning 2010 until Mid 2028
Funding: EU-Interreg, Bavarian Nordic, 270.000 EUR
Project Details:
Ticks transmit various human and animal pathogens. With regard to pathogens, the vector function of ticks for the causative agent of Lyme borreliosis (Borrelia burgdorferi sensu lato complex), human and animal granulocytic anaplasmosis and tick-borne encephalitis (TBE virus) is of particular importance. Studies on the abundance and distribution of ticks and their pathogens are therefore essential for assessing the One Health risk. Regarding tick-transmitted pathogens, this project collects data not only for Germany but also at the international level.
Results:

Rapp, J., Springer, A., Strube, C. (2024) Ixodes ricinus ticks survive flooding.  Ticks and Tick-Borne Diseases 15, 102417

 

Springer, A., Jordan, D., Höltershinken, M., Barutzki, D., Strube, C. (2024) Endemisation and management of Babesia divergens on a beef production farm. Current Research in Parasitology & Vector-Borne Diseases 6, 100188

 

Springer, A., Lindau, A., Probst, J., Fachet, K., Schäfer, I., Dobler, G., Mackenstedt, U., Strube, C. (2024) Germany-wide Citizen Science study reveals spread of Babesia canis-infected Dermacentor reticulatus ticks by dogs travelling within the country. Current Research in Parasitology & Vector-Borne Diseases 6, 100d187

 

Probst, J., Springer, A., Fingerle, V., Strube, C. (2024) Frequency of Anaplasma phagocytophilum, Borrelia spp. and coinfections in Ixodes ricinus ticks collected from dogs and cats in Germany. Parasites & Vectors 17, 87

 

Probst, J., Springer, A., Topp, A.-K., Bröker, M., Williams, H., Dautel, H., Kahl, O., Strube, C. (2023) Winter activity of questing ticks (Ixodes ricinus and Dermacentor reticulatus) in Germany − Evidence from quasi-natural tick plots, field studies and a tick submission study.  Ticks and Tick-Borne Diseases 14, 102225

Cooperation Partners:

Dr. O. Kahl, tick-radar GmbH

Prof. Dr. U. Mackenstedt, Universität Hohenheim

Dr. V. Fingerle, Nationales Referenzzentrum für Borrelien, Oberschleißheim

Prof. Dr. G. Dobler, Nationales Konsiliarlabor für FSME, München

Dr. L. Chitimia Dobler, Fraunhofer-Institut für Immunologie, Infektions- und Pandemieforschung

Show Details
Long-term monitoring of tick abundance and prevalence of Borrelia spp. and other pathogens in the city of Hannover, Germany
Langzeit-Monitoring der Zeckenabundanz und Befallshäufigkeit mit Borrelia spp. und anderen Pathogenen im Stadtgebiet Hannover
Project Investigators: Prof. Dr. C. Strube, PhD; Dr. A. Springer
Duration: Beginning 2005 until Beginning 2028
Project Details:
Ticks of the genus Ixodes transmit various human and animal pathogens. In this long-term project running since 2005, pathogen prevalence in ticks in the city of Hannover, Germany, is monitored to investigate potential effects of climate change. In addition to the infection status of the ticks, the tick density in the Hannover area will also be determined.
Results:

Glass, A., Springer, A., Raulf, M.-K., Fingerle, V. Strube, C. (2023) 15-year Borrelia prevalence and species distribution monitoring in Ixodes ricinus/inopinatus populations in the city of Hanover, Germany. Ticks and Tick-Borne Diseases 13, 102074

 

Glass, A., Springer, A., Strube, C. (2022) A 15-year monitoring of Rickettsiales (Anaplasma phagocytophilum and Rickettsia spp.) in questing ticks in the city of Hanover, Germany. Ticks and Tick-Borne Diseases 13, 101975

 

Hauck, D., Springer, A., Chitimia-Dobler, L., Strube, C. (2020) Two-year monitoring of tick abundance and influencing factors in an urban area (city of Hanover, Germany). Ticks and Tick-Borne Diseases 11, 101464

 

Blazejak, K., Raulf, M.-K., Janecek, E., Jordan, D., Fingerle, V., Strube, C. (2018) Shifts in Borrelia burgdorferi (s.l.) geno-species infections in Ixodes ricinus over a 10-year surveillance period in the city of Hanover (Germany) and Borrelia miyamotoi-specific Reverse Line Blot detection. Parasites & Vectors 11, 304

 

Blazejak, K., Janecek, E., Strube, C. (2017) A 10-year surveillance of Rickettsiales (Rickettsia spp. and Anaplasma phagocytophilum) in the city of Hanover, Germany, reveals Rickettsia spp. as emerging pathogens in ticks. Parasites & Vectors 10, 588

Cooperation Partners:

Dr. V. Fingerle, Nationales Referenzzentrum für Borrelien, Oberschleißheim

Show Details
INsect-based Sustainable Poultry feed for ImpRoved food safEty - INSPIRE
Erhöhung der Lebensmittelsicherheit der Geflügelfleischerzeugung durch Einsatz von Nebenströmen aus der Insektenlarvenproduktion in der Geflügelfütterung
Project Investigators: Prof. Dr. J. Hankel; Chiara Müller
Duration: April 2026 until 2027
Funding: QS-Wissenschaftsfonds, 34.980 EUR
Project Details:
As part of the project, a practical feeding concept will be developed that utilizes a protein-rich by-product stream from insect production and, while taking ecological and economic aspects into account, enhances food safety by reducing zoonotic pathogens in fresh poultry products.
Show Details
Influence of replacing meat with the microalgae Spirulina spp. and Chlorella spp. on the physicochemical and microbiological properties of cooked sausage made from pork, beef and chicken meat
Einfluss des Ersatzes von Fleisch durch die Mikroalgen Spirulina spp. und Chlorella spp. auf die physikochemischen und mikrobiologischen Eigenschaften von Brühwurst aus Schweine-, Rind- und Hähnchenfleisch
Project Investigators: Prof. Dr. Carsten Krischek; Dr. Lisa Siekmann; Prof. Dr. Madeleine Plötz
Duration: January 2026 until December 2027
Funding: Fritz-Ahrberg-Stiftung, 25.000 EUR
Project Details:
Alternative ingredients such as plants or insects as substitutes for meat in (vegetarian or vegan) meat products have been increasingly researched in recent years and are already being used in some commercial products. Algae are also an interesting alternative to meat, as they are also high in protein. A distinction is made between microalgae and macroalgae. Scientific studies with microalgae species such as Chlorella spp. or Spirulina spp. as meat substitutes in meat products have shown that their addition has an influence on physicochemical parameters, especially colour. Since the studies published to date have mostly used only one microalgae species in a few concentrations with one type of meat (mostly pork), the proposed project aims to produce cooked sausages from two different microalgae species, Chlorella spp. or Spirulina spp. in different concentrations to replace the meat content, varying the type of meat replaced (pork, beef, chicken). In addition to physicochemical parameters such as pH value or colour, microbiological parameters (after inoculation, if applicable) will also be examined during storage in a protective gas atmosphere in order to evaluate the influence of meat replacement by microalgae during storage in retail outlets.
Show Details
Sperm selection without centrifugation - development of a microfluidic chip system for sperm selection from larger sample volumes
Spermienselektion ohne Zentrifugation - Entwicklung eines Mikrofluidic-Chip Systems zur Spermienselektion größerer Probenvolumina
Project Investigators: Harald Sieme; Harriette Oldenhof; Julius Goeke
Duration: April 2025 until 2027
Project Details:
The aim of this work is to develop a practical microfluidic chip sperm selection method for large-volume (10-20 ml) initial samples of diluted stallion semen. This method is intended to replace semen preparation by centrifugation and increase fertilisation rates after insemination.
Cooperation Partners:

Niedersächsisches Landgestüt Celle

Show Details
Cosmic Radiation response in the simplest animal on Earth: Trichoplax, a new evolutionary animal model for Space Biology Research
Cosmic Radiation response in the simplest animal on Earth: Trichoplax, a new evolutionary animal model for Space Biology Research
Project Investigators: Bernd Schierwater
Duration: 2025 until 2027
Funding: Australian Nuclear Science and Technology Organisation (ANSTO) and German Aerospace Center (DLR), 130.000 EUR
Project Details:
The high-energy cosmic radiation has a decisive influence on all manned space missions. The effect of this radiation on the model organism Trichoplax adhaerens (Placozoa) will be investigated in this project. Placozoans are the most simply organized multicellular animals and can give us crucial clues about the effect of cosmic radiation on humans.
Cooperation Partners:

Patrick Humbert, La Trobe University, Australia

Jens Hauslage, DLR, Köln

Show Details
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