Research

Funding: Ministerium für Wissenschaft und Kultur Niedersachsen, 100.630 EUR

Project Details:
Das beantragte Projekt ConnEx adressiert mit den Lehrenden und den technischen wie didaktischen Service- und Support-Einrichtungen an den niedersächsischen Hochschulen zwei für die Dachinitiative Hochschule.digital Niedersachsen strategisch relevante Akteursgruppen und zielt auf eine strategische Förderung der Vernetzung, des Austauschs und Transfers innerhalb dieser Gruppen. Die Projektleitung hat die Leuphana Universität Lüneburg.

Results:

https://hochschuledigital-niedersachsen.de/home/connex-vernetzung-von-expertinnen-und-services/

Cooperation Partners:

Hochschule für angewandte Wissenschaft und Kunst, Hochschule für Bildende

Künste Braunschweig; Hochschule Emden/Leer, Hochschule Hannover, Hochschule für Musik, Theater und Medien Hannover, Hochschule Osnabrück, Jade

Hochschule, Leuphana Universität Lüneburg, Leibniz Universität Hannover,

Medizinische Hochschule Hannover, Ostfalia Hochschule für angewandte Wissenschaften, Technische Universität Braunschweig, Technische Universität Clausthal, Georg-August-Universität Göttingen, Stiftung Universität Hildesheim, Carl von Ossietzky Universität Oldenburg, Universität Osnabrück, Universität Vechta, ELAN e.V.

Funding: Bundesamt für Seeschifffahrt und Hydrographie, BSH, 80.857 EUR

Project Details:
The aim of the research project is to answer scientific questions related to the effects of offshore wind farms on harbour porpoises in German waters. Therefore, both the sound-related effects on the population of harbour porpoises that occur during construction and the cumulative effects from the construction of offshore wind farms, for which an assessment concept will be developed (FP 2), will be investigated. The objective of this research project is to establish the cause-effect relationship between sound exposure and harbour porpoise occurrence as well as to evaluate the effectiveness of measures used to reduce effects on harbour porpoises (noise mitigation and deterrence). First, underwater noise recordings during the construction of offshore wind farms will be analysed with regard to the noise emission from the pile driving. Based on this data and considering physical area-specific parameters, the sound propagation will be modelled. The modelling enables to estimate noise emissions in the entire study area. A model will be used to determine whether the existing data are sufficient to explain effects on the occurrence of harbour porpoises. In a study, data will be identified, criteria established and, with a model, their applicability tested to investigate cumulative effects of offshore wind farm construction on the occurrence of harbour porpoises.
The work in this project will answer the following questions:
1)How can the effects of anthropogenic noise emissions during the construction of offshore wind turbines on harbor porpoises be assessed cumulatively?
2)Can the collected data on pile-driving noise, deterrence and porpoise detections as well as construction-related shipping sufficiently explain the effect of the construction work on the occurrence of harbour porpoises?
An evaluation that takes into account all constructed wind farms has not been carried out yet, but is imperative in the future, among other things to evaluate the success of the application and further developments of noise mitigation measures. The evaluation of the current noise mitigation concept and state of the art using data and findings from the previous projects make an important contribution to the planning of the upcoming further expansion of offshore wind energy.

Cooperation Partners:

JASCO Applied Sciences

Funding: BMBF, 45.234 EUR

Project Details:
The focus is on the problem that we classify animals according to human standards, such as those we love and those we fight against. Protecting humans from diseases that originate in the animal kingdom requires measures that are maximally detrimental to animals. The retreat weeks will focus on current and controversial research into zoonoses. Ethics and moral philosophy must also provide answers to the question of what boundaries we should draw for ourselves in these difficult decisions and what criteria we should use as a basis. The results are to be bundled into a model that can be used both as a model for questions in the scientific community and as a touchstone for academic discourse on an appropriate relationship to the "animal"

Results:

Triggered by COVID-19, zoonoses have moved into the spotlight of public interest.

In zoonosis research in particular, it is important to weigh up the potential benefits for humans against the actual harm to laboratory animals.

During a retreat week, experts discussed and prepared helpful contributions on conflicts in the field of "zoonosis research on companion animals". Based on real case constellations, an argumentative path through the numerous value contradictions was shown, which represents an extreme condensation of fundamental animal ethical conflicts based on real, concrete scenarios.

The project initially dealt with the clarification of terms: what makes an animal a laboratory animal, what makes it a pet? Where do the terms overlap and what is the legal situation in different countries?

The special nature of companion animals in the context of zoonoses was explored in an ethical and scientific manner. Younger researchers in particular were confronted with the ethical aspect of zoonosis research for the first time and found an ethical exchange on the topic very helpful.

The results of the project were documented in the special issue of the Journal of Applied Animal Ethics Research published in fall 2023 and provide a good basis for a refined model for future interdisciplinary writing projects. A continuation of the project from summer 2024 in the form of European summer schools is planned.

Funding: Ministerium für Wissenschaft und Kultur (MWK) Niedersachsen, 250.000 EUR

Project Details:
The DILEAVET project aims to optimize the existing framework conditions at the University of Veterinary Medicine Hannover for the design of digital teaching, the examination system and for the teaching of clinical-practical skills, and thus at the same time to create conditions that support the "FERVET" project.

Results:

Im Projekt DILEAVET wurden u. a. folgende Ergebnisse in den 4 Arbeitspaketen (AP) erzielt:

Im AP 1 "Weiterentwicklung von digitalem Schulungsmaterial und -angeboten" wurde ein Vermittlungskonzept erarbeitet. Für die Themenfelder elektronische Prüfungen und digitales Lehren und Lernen wurden bereits bestehende Schulungsmaterialien aktualisiert, neue Anleitungen angefertigt sowie Online-Seminare durchgeführt.

Im AP 2 "Wissenstransfer" wurden Videos angefertigt, welche auf dem YouTube-Kanal der TiHo "TiHoVideos" oder intern zur Verfügung stehen; außerdem wurde u.a. ein virtuelles Mikroskop für das Fach Mikrobiologie für die Studierenden und als OER-Beitrag eine Sammlung zu Modellen erstellt.

Im AP 3 "Entwicklung und Etablierung von Modellen und Lernstationen im CSL" erfolgte eine Entwicklung von Escape-Room-Szenarien und deren Etablierung in Lehrveranstaltungen sowie die Entwicklung und Etablierung von Simulatoren und Lernstationen zum Thema Zier- und Wildvögel-Tierarten.

Im AP 4 "Digitalisierungskonzept zu kommunikativen Kompetenzen" wurden Best-Practice-Videos und Worst-Case-Videos zur Schulung kommunikativer Kompetenzen erstellt.

 

OER-Beitrag auf "twillo"

https://www.twillo.de/edu-sharing/components/render/9a067b21-c565-4894-a380-d2630c8f8fc8

 

TiHoVideos:

https://www.youtube.com/user/tihovideos

 

ENZIG-STROHM A, KNOLL M T, BETTERMANN V, CHODZINSKI A, HEINEMANN I, TIPOLD A, WISSING S, SCHAPER E: Tierschutzgerechte Vermittlung klinisch-praktischer Fertigkeiten. Tierschutztagung 2023, 16.03.2023 - 18.03.2023, München

Funding: Bundesministerium für Ernährung und Landwirtschaft (BMEL); Bundesanstalt für Landwirtschaft und Ernährung, 7.975 EUR

Project Details:
Development of a multifunctional barn concept for the animal-friendly keeping of dual-purpose chickens and brother cocks from chicks to food

Cooperation Partners:

Hochschule Osnabrück, Tierhaltung und Tierprodukte (Prof. Dr. R. Andersson)

Fachhochschule Südwestfalen, Fachbereich Agrarwirtschaft, Prof. Dr. M. Mergenthaler

Universität Bonn, Institut für Tierwissenschaften, Dr. I. Tiemann

Universität Bonn, Verfahrenstechnik in der Tierischen Erzeugung, Prof. Dr. W. Büscher

Funding: Niedersächsischen Ministeriums für Wissenschaft und Kultur , 3.452 EUR

Project Details:
The aim was to create a course on the topic of "Basic training in the use of fluorescence microscopy" for students of biology and veterinary medicine via the documentation system in the TiHo Moodle platform. This module can be completed by the students in self-study. It is underpinned by texts, videos and subject-specific questions that must be answered after processing and viewing the videos. Essential parts of the content are also made available online as summarizing units as OER in the Twillo portal and are particularly suitable for students from natural science courses, pupils and trainees in (veterinary) medical professions.

Funding: SprinD GmbH, 263.866 EUR

Project Details:
The viral genome of an RNA virus is released into the cell, where the viral genome is amplified and its transcripts translated into proteins to form more copies the virus. CRISPR/Cas13 enzymes cleave different sites of the viral genome and its transcripts through a combination of crRNAs. Proliferation of the virus is blocked and transcripts to be translated into viral proteins are reduced.

Cooperation Partners:

Universitätsmedizin Göttingen (UMG), Prof. Elisabeth Zeisberg

Funding: Technische Informationsbibliothek Hannover (TIB); FKZ 56000016-39/TiHo, 3.505 EUR

Project Details:
The topic of "mobile slaughtering" is currently moving into the focus of the meat industry, as this particularly meets the aspects of regionality and animal welfare. It can be assumed that animals are subjected to more stress during conventional slaughtering, especially during transport to the slaughterhouse, than when they are gently stunned and slaughtered in their usual environment. So-called "mobile slaughtering" is subject to special and partly new legal backgrounds with associated official approval procedures. Within the framework of the project, a teaching unit for veterinary students on the subject of "mobile slaughtering" is to be created as a supplement to and comparison with conventional slaughtering. The teaching unit will address legal backgrounds, animal welfare as well as food quality and safety. In addition, further teaching material (presentations, legal texts, etc.) will be created, prepared and made available to the students on the TiHo-Moodle learning platform together with the teaching unit. The teaching unit can be used by all students of veterinary medicine in the German-speaking countries via the portal twillo. In addition, it is tangential to the field of agriculture (agrarian sector), the butcher and butchery sector, as well as other veterinarians who are already active in the public veterinary sector and come into contact with the associated licensing procedures. Likewise, the teaching unit enables the interested consumer community to gain insight into this field.

Funding: Niedersächsisches Ministerium für Wissenschaft und Kultur, 50.000 EUR

Project Details:
Mit dem Innovation plus-Projekt wird ein Training klinisch-praktischer und kommunikativer Fertigkeiten mit anschließender formativer elektronischer eOSCE-Prüfung (Electronic Objective Structured Clinical Examination) für Studierende, die ihren Zyklus des Praktischen Jahres in der Klinik für Heimtiere, Reptilien, Zier- und Wildvögel der Stiftung Tierärztliche Hochschule Hannover absolvieren, konzipiert und umgesetzt werden. Das Training dient der Vorbereitung der Studierenden auf ihr Praktisches Jahr sowie der tierärztlichen Tätigkeit im Anschluss an das Studium. In dem Zusammenhang werden Modelle und Simulatoren sowie Lernstationen für den Heimtiersektor erstellt für die Vermittlung klinisch-praktischer und kommunikativer Fertigkeiten. Im Anschluss an das praktische Training erfolgt eine Überprüfung der erlernten Fertigkeiten mittels eOSCE-Prüfung.

Funding: This work was supported by COVID-19 Research Network of the State of Lower Saxony (COFONI) with funding from the Ministry of Science and Culture of Lower Saxony, Germany (14-76403-184) and by PRACTIS—Clinician Scientist Program of Hannover Medical School, funded by the German Research Foundation (DFG-ME3696/3-1)., 50.000 EUR

Project Details:
Vaccination is an important measure in controlling the COVID-19 pandemic. However, there were pharmocovigilance concerns as a very rare but potentially disastrous complication was identified after application with the ChAdOx1 nCoV-19 vaccine, i.e. cerebral sinus thrombosis, but also further thrombotic complications including ischemic stroke. Meanwhile, the most likely mechanism has been identified as platelet factor 4 (PF4) antibody mediated immune thrombotic thrombocytopenia, a mechanism which is already known from heparin-induced thrombocytopenia (HIT). Interestingly NETs were suggested to be critical for thrombus formation in the HIT-pathophysiology as well. Markers of NETosis were observed in platelet-rich thrombi in the lungs of mice with HIT. Therefore, NETs might also be involved in vaccine-induced immune thrombotic thrombocytopenia (VITT) mediated thrombotic complications and might therefore be a common trunk in the pathogenesis of COVID-19 and vaccine-induced complications. Moreover, biomarkers reflecting NETs burden in the circulation and within tissue specimens (e.g. cerebral thrombi) may be suitable as diagnostic, therapeutic or prognostic targets in thrombotic diseases. Most importantly, there is a tremendous need to identify patients at risk for cerebrovascular complications due to both COVID-19 and VITT. The proposed project ISI-VITT is intended to contribute to addressing this issue.

Cooperation Partners:

Cerebrovascular Research Group (Head: Prof. Dr. Karin Weissenborn), Deptartment of Neurology, Medical School Hannover: Dr. Ramona Schuppner & Dr. Gerrit M. Grosse

Prof. Dr. Christine Falk, Institute for Transplantation Immunology, Medical School Hannover