Research

Funding: MELUND, 56.077 EUR

Project Details:
Research on marine mammals started in Büsum after the first seal mortality in 1988/89. The aim of the scientists is to study the biology and ecology of marine mammals and to assess the impact of humans on the animals, their health and their population. The scientific focus is on studies of health (exposure to pollutants, underwater noise, stress, immune system, infectious diseases, etc.) as well as behaviour, habitat use, population densities and impacts of anthropogenic interventions. Among other lines of research, the scientists are currently investigating the effects of underwater noise (e.g. from explosions, offshore wind turbines, shipping) on the behaviour and health of seals and harbour porpoises, chemical pollution and waste, disturbances and fishing on marine mammals. The stranding network ensures that whales and seals found on the coasts of Schleswig-Holstein can be reported, recovered and necropsied. The state of health is determined by means of further histological, microbiological and parasitological examinations. In this project, the tissues of porpoises found dead in the North Sea and the Baltic Sea will be examined for specific pollutants and the auditory apparatus will be analysed.
The following pollutants will be investigated in the liver and fat of harbour porpoises from waters in Schleswig-Holstein: polychlorinated biphenyls (PCBs) and derivatives, dichloro-diphenyl-trichloroethane (DDT), polybrominated diphenyl ethers (PBDEs) and mercury (Hg). The results of the toxicological investigation will be combined with the data on health status from the autopsies and an ecotoxicological assessment will be made. The results will be used for the development of further investigations for the various agreements, such as HELCOM, OSPAR, MSRL, and development of indicators.
For investigations of the auditory apparatus, dead harbour porpoises recovered within the framework of the small cetacean monitoring programme of the Land of Schleswig-Holstein should be collected immediately after reporting in order to remove and preserve the ears as fresh as possible for the investigation. In particular, harbour porpoises found dead after blasting and other impulse sound events as well as by-catches and live strandings shall be included. High-resolution computed tomography scans of the ear bones will be performed as well as confocal microscopic and histological examinations.
The studies on the auditory apparatus of harbour porpoises carried out in this project will be considered in the context of ongoing or completed studies at ITAW with similar questions. The results of this project will be used to assess whether changes in various structures of the auditory pathways may have been caused by exposure of harbour porpoises to explosions or other impulsive sound events.

Results:

Bericht an das Ministerium für Energiewende, Klimaschutz, Umwelt und Natur des Landes Schleswig-Holstein

https://www.schleswig-holstein.de/DE/fachinhalte/A/artenschutz/Downloads/untersuchungSchweinswale2021.pdf?__blob=publicationFile&v=1

Funding: This work was supported by COVID-19 Research Network of the State of Lower Saxony (COFONI) with funding from the Ministry of Science and Culture of Lower Saxony, Germany (14-76403-184) and by PRACTIS—Clinician Scientist Program of Hannover Medical School, funded by the German Research Foundation (DFG-ME3696/3-1)., 50.000 EUR

Project Details:
Vaccination is an important measure in controlling the COVID-19 pandemic. However, there were pharmocovigilance concerns as a very rare but potentially disastrous complication was identified after application with the ChAdOx1 nCoV-19 vaccine, i.e. cerebral sinus thrombosis, but also further thrombotic complications including ischemic stroke. Meanwhile, the most likely mechanism has been identified as platelet factor 4 (PF4) antibody mediated immune thrombotic thrombocytopenia, a mechanism which is already known from heparin-induced thrombocytopenia (HIT). Interestingly NETs were suggested to be critical for thrombus formation in the HIT-pathophysiology as well. Markers of NETosis were observed in platelet-rich thrombi in the lungs of mice with HIT. Therefore, NETs might also be involved in vaccine-induced immune thrombotic thrombocytopenia (VITT) mediated thrombotic complications and might therefore be a common trunk in the pathogenesis of COVID-19 and vaccine-induced complications. Moreover, biomarkers reflecting NETs burden in the circulation and within tissue specimens (e.g. cerebral thrombi) may be suitable as diagnostic, therapeutic or prognostic targets in thrombotic diseases. Most importantly, there is a tremendous need to identify patients at risk for cerebrovascular complications due to both COVID-19 and VITT. The proposed project ISI-VITT is intended to contribute to addressing this issue.

Cooperation Partners:

Cerebrovascular Research Group (Head: Prof. Dr. Karin Weissenborn), Deptartment of Neurology, Medical School Hannover: Dr. Ramona Schuppner & Dr. Gerrit M. Grosse

Prof. Dr. Christine Falk, Institute for Transplantation Immunology, Medical School Hannover

Funding: Common Wadden Sea Secretariat, 21.010 EUR

Project Details:
Harbor seals (Phoca vitulina) and grey seals (Halichoerus grypus) are the largest animals found in the Wadden Sea in Denmark, Germany and the Netherlands. Since the seals were placed under the protection of the Trilateral Wadden Sea Agreement and especially since the establishment of the Wadden Sea National Parks in Lower Saxony, Hamburg and Schleswig-Holstein, the severely depleted populations of seals and grey seals have been able to recover. The unique value of the marine mammals' habitat was confirmed in 2009 when the Wadden Sea was designated a UNESCO World Heritage Site. Seals and grey seals are "charismatic species" and therefore play an important role for recreation and tourism. This is also true for the Wadden Sea National Parks, where marine mammals are popular and serve as a tourist marketing tool.
The marine mammals are promoted as a tourist attraction in various places in the Wadden Sea, especially through organised seal watching trips. They thus represent an important
ecosystem service contributing to value generation for local economies.
These human-wildlife relationships are not without conflict: for example, the overlap of the high tourist season with the seals' whelping and nursing season from mid-June onwards is problematic. While observation cruises carried out by established shipping companies adhere to standards such as minimum distances to the seal banks and navigating at an adapted speed, private pleasure boats, wind and kite surfers are much more difficult to control. At the same time, less national park-specific tourism offers with event character have also increased in recent years. It is possible that this trend will continue due to the increased
domestic tourism demand observed during the Corona crisis. The effects of these different forms of tourism in the Wadden Sea on the stress levels and behaviour of marine mammals have not yet been sufficiently researched. Therefore, these questions will be investigated from an international and multidisciplinary perspective.
Information on behaviour can be obtained through observations and telemetry, and existing data will be analysed in this regard.
On the other hand, the importance of marine mammals for tourism will be investigated from a tourism perspective. The aim of the project is to present a scientifically sound framework that takes into account both the interests of wildlife and nature conservation in terms of minimising disturbance, and at the same time the needs of the tourism sector and the local economy in terms of business in terms of enhancing tourist attractions and developing attractive wildlife and nature experiences.

Cooperation Partners:

Prof. Dr. Julius Arnegger, International Tourism Management, DITF - German Institute for Tourism Research, West Coast University of Applied Sciences, 25746 Heide, Germany

Funding: Nationalparverwaltung "Nieders. Wattenmeer" Wilhelmshaven, 39.080 EUR

Project Details:
The aim of the project is a survey of the local grey seal population in the entire Lower Saxony and Hamburg Wadden Sea during the birthing season (November-December) and at the time of the fur change (March-April).
On five trilaterally coordinated dates (three during the birthing season; two during the fur-change period), airborne surveys will be conducted with a single-engine aircraft. During the aerial surveys of the tidal flats, a high-resolution SLR camera will be used to photograph the haul-outs. In order to determine the number of young born as well as the total population, the photos taken are subsequently analyzed on the computer.

Results:

Schop J., Abel C., Brasseur S., Galatius A., Jeß A., Meise K., Meyer J., van Neer A., Stejskal O., Siebert U., Teilmann J., Thøstesen C. B. (2022) Grey Seal Numbers in the Wadden Sea and on Helgoland in 2021-2022. Common Wadden Sea Secretariat, Wilhelmshaven, Germany.

https://www.waddensea-worldheritage.org/resources/2021-2022-grey-seal-report

Funding: Projektförderung aus dem Europäischen Landwirtschaftsfonds für die Entwicklung des ländlichen Raums (ANBest-ELER 2021, Europäischen Innovationspartnerschaft "Produktivität und Nachhaltigkeit in der Landwirtschaft" (EIP Agri), 89.794 EUR

Project Details:
Suboptimal availability and quality of drinking water as well as a lack of hygiene in water pipes on pig farms can cause animal welfare and health problems. Insufficient water intake due to technical deficiencies, low palatability due to e.g. biofilm formation in the pipes or a restrictive water supply represent a massive stressor for animals and can lead to health impairments that promote other diseases (e.g. ear and tail injuries, diarrhea).
In this project, a new drinking water pipe cleaning concept for piglet rearing farms will be established and tested for practical use in two rearing barns. The system, developed in a collaborative project and tested under laboratory conditions, will be used to clean water pipes contaminated with plaque, to destroy Salmonella reservoirs in the pipes, and to reduce endotoxin contamination. It is exspected, that ear and tail lesions will be reduced after cleaning the drinking water pipes in case that they are related to endotoxins. After technical, chemical and microbiological analyses, as well as examinations of the piglets, the drinking water pipe cleaning is carried out on the farms. A newly developed mobile flushing device and a new substance containing tartaric acid and catalytic additives are used. The substance is highly effective against biofilms and also destroys the genetic material of pathogens. The effects of this cleaning concept will be measured and evaluated on two farms in three baches respectively.

Cooperation Partners:

Landwirtschaftliche Betriebe

Aumann Hygienetechnik

ConVet GmbH&Co. KG

Project Details:
Frequencies of Actinobacillus pleuropneumoniae isolates resistant against various antimicrobial substances will be compared in the years 2006-2021. Frequencies of coinfecting agents will be determined.

Results:

doi: 10.3389/fvets.2021.802570

Funding: Herbonis Animal Health GmbH Rheinstrasse 30 4302 Augst BL, Schweiz, 4.300 EUR

Project Details:
Solanum glaucophyllum (waxy nightshade) is one of the few plants that naturally produces 1,25-dihydroxycholecalciferol glycosides (1,25(OH)2D3-gly). In the literature it is mentioned that the glycosides are cleaved before absorption and thus only the aglycone is absorbed. However, no data are known so far that confirm this assumption analytically. In a multi-stage approach, this question is to be clarified in vitro. To do this, a number of preliminary tests must first be carried out, including one focusing on possible cell toxicity. Since the cell toxicity of 1,25(OH)2D3-gly can only be extrapolated from the data for synthetic 1,25(OH)2D3 to a limited extent, this experiment serves to determine the maximum possible dose.

Cooperation Partners:

Herbonis Animal Health GmbH

Rheinstrasse 30

4302 Augst BL, Schweiz

Funding: EU, 8.320 EUR

Project Details:
The overall aim of the HELCOM BLUES project is to support regional capacity, coordination and cooperation with regards to developing effective measures to secure good status of the marine environment. This includes provisioning, and making available, necessary knowledge to advance the development and implementation of joint measures addressing common pressures, as well as to provide concrete support to the decision-making process within the Baltic Sea region.
The task carried out by TiHo focuses on highly mobile and under-reported groups (here: cetaceans), and considers several aspects identified in recent HELCOM review processes to be knowledge/assessment gaps and aspects of high regional priority. The harbour porpoise can be categorised as both a highly mobile and an under-reported species in the Baltic Sea region. At present, there are no functional regional HELCOM indicator(s) to assess status for abundance or distribution, which are two of the primary Marine Strategy Framework Directive criteria under MSFD D1. This clear gap was identified as a high priority for the HELCOM region. This task will provide support for the HELCOM indicator team and focus on improving methods and operational assessments of harbour porpoise abundance by HOLAS III, and on harmonising methods of assessment with other EU regions (i.e. OSPAR and HELCOM). The main aspects addressed by TiHo are:
1) Establishment of a harmonised approach to indicator development for harbour porpoises between HELCOM and OSPAR (of particular relevance to shared marine areas);
2) Assessing trend in abundance for assessment of the Belt Sea population;

Results:

final report of the EU project "HELCOM BLUES"

https://blues.helcom.fi/wp-content/uploads/2023/09/HELCOM-BLUES_Activity_2.4-Harbour-porpoise-Main-report.pdf

Cooperation Partners:

Project coordinator

Helsinki Commission (HELCOM), Finland

Partners

Kiel Institute for the World Economy (IfW), Germany

University of Hamburg, Germany

Natural Resources Institute Finland (LUKE), Finland

Finnish Environment Institute (SYKE), Finland

Swedish University of Agricultural Sciences, Department of Aquatic Resources (SLU Aqua), Sweden

Stockholm University (SU), Sweden

Swedish Meteorological and Hydrological Institute (SMHI), Sweden

Swedish Agency for Marine and Water Management (SwAM), Sweden

Tallinn University of Technology (TalTech), Estonia

University of Tartu (UT), Estonia

Center for Environmental Policy (AAPC), Lithuania

Latvian Institute of Aquatic Ecology, Latvia

Funding: ALZCHEM, 39.065 EUR

Project Details:
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Funding: K+S Minerals and Agriculture GmbH, 13.808 EUR

Project Details:
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