Biostabilization: Many biomedical implants or "tissue-engineered" constructs contain biomolecules or cells that degrade without appropriate preservation strategies. Implants must be readily available for patient treatment. However, storage and transportation of implants from the day of manufacture to use under physiological conditions is complicated and costly. Therefore, preservation methods need to be developed and established. For example, cryopreserved endothelialized biohybrid lung tissue can be preserved long-term and is available when needed. Decellularized heart valves and pericardial patches can be freeze-dried for storage and transport at room temperature. Biostabilization is an essential step in the development of implants and "tissue-engineered" constructs with cellular components or biomolecules to ensure availability in acute situations and to enable intercontinental transport of replacement tissues.
