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2 results.
Photodynamic inactivation of bacteria in semen: an alternative to antibiotics in pig breeding
Photodynamische Inaktivierung von Bakterien im Sperma - eine Alternative zu Antibiotika in der Schweinezucht ([PodiPig]
Project Investigators: Prof. Dagmar Waberski; Dr. Anne-Marie Luther
Duration: January 2026 until January 2029
Funding: BMLEH, 355.080 EUR
Project Details:
In pig breeding, the continuous use of antibiotics in liquid-preserved semen for artificial insemination is increasingly leading to antimicrobial resistance and environmental burden. Worldwide, the pig industry is under pressure to identify and implement effective and sustainable alternatives for microbial control in semen. The goal is to replace antibiotics in the preservation medium with an innovative technology: photodynamic inactivation (PDI) of bacteria. In an interdisciplinary consortium with partners from industry and science, the PDI technique established in a previous project will be translated into a prototype and its antimicrobial efficacy will be enhanced against specific problematic microorganisms. This is intended to bring a biosafe alternative to antiobiotics for liquid-preserved boar semen stored at 17°C to the next technology readiness level.
Cooperation Partners:

Humboldt-Universität zu Berlin

Minitüb GmbH

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Growth dynamic and vitality of Leptospira in preserved boar semen: Influence of antibiotics and storage temperature
Wachstumsdynamik und Vitalität von Leptospiren in konserviertem Ebersperma: Einfluss von Antibiotikum und Lagerungstemperatur
Project Investigators: Prof. Dagmar Waberski; Dr. Anne-Marie Luther
Duration: Mid 2026 until Mid 2028
Funding: Förderverein Bioökonomieforschung (FBF e.V.), 44.000 EUR
Project Details:
With the ongoing development of antibiotic‑free preservation methods for boar semen, the question arises whether these are also effective against leptospires. It should be noted that, to date, the efficacy of conventional antibiotics against leptospires in preserved semen has not been demonstrated in the available literature. The reason for this is that leptospires require special and prolonged cultivation methods.
Using the newly established assay, the growth of leptospires in long‑term preserved boar semen will be investigated. In particular, the influence of gentamicin and storage temperature will be assessed. Ultimately, the efficacy and necessity of antibiotics against leptospires will be evaluated.
Cooperation Partners:

IVD Gesellschaft für Innovative Veterinärdiagnostik mbH

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