further Publications

Prajeeth K. Chittappen, PhD

Schweitzer, F., Letoha, T., Osterhaus, A., & Prajeeth, C. K. (2025). Impact of tick-borne Orthoflaviviruses infection on compact human brain endothelial barrier. International Journal of Molecular Sciences, 26(5), Article 2342. https://doi.org/10.3390/ijms26052342
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Kubinski, M., Beicht, J., Gerlach, T., Aregay, A., Osterhaus, A. D. M. E., Tscherne, A., Sutter, G., Prajeeth, C. K., & Rimmelzwaan, G. F. (2024). Immunity to tick-borne encephalitis virus NS3 protein induced with a recombinant modified vaccinia virus Ankara fails to afford mice protection against TBEV infection. Vaccines, 12(1), Article 105. https://doi.org/10.3390/vaccines12010105
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Leroux-Roels, I., Prajeeth, K. C., Aregay, A., Nair, N., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., Kardinahl, S., Pelz, S., Bauer, S., D’Onofrio, V., Alhatemi, A., Jacobs, B., De Boever, F., Porrez, S., Waerlop, G., Punt, C., Hendriks, B., von, van de, et al. (2024). Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against rift valley fever in healthy adults: a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial. The Lancet: Infectious Diseases, 24(11), 1245–1253. https://doi.org/10.1016/S1473-3099(24)00375-X
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Prajeeth, C. K., Zdora, I., Saletti, G., Friese, J., Gerlach, T., Wilken, L., Beicht, J., Kubinski, M., Puff, C., Baumgärtner, W., Kortekaas, J., Wichgers Schreur, P. J., Osterhaus, A. D. M. E., & Rimmelzwaan, G. F. (2024). Immune correlates of protection of the four-segmented Rift Valley fever virus candidate vaccine in mice. Emerging Microbes & Infections, 13, Article 2373313. https://doi.org/10.1080/22221751.2024.2373313
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Beicht, J., Kubinski, M., Zdora, I., Puff, C., Biermann, J., Gerlach, T., Baumgärtner, W., Sutter, G., Osterhaus, A., Prajeeth, C. K., & Rimmelzwaan, G. F. (2023). Induction of humoral and cell-mediated immunity to the NS1 protein of TBEV with recombinant Influenza virus and MVA affords partial protection against lethal TBEV infection in mice. Frontiers in Immunology, 14, Article 1177324. https://doi.org/10.3389/fimmu.2023.1177324
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Kubinski, M., Beicht, J., Zdora, I., Biermann, J., Puff, C., Gerlach, T., Tscherne, A., Baumgärtner, W., Osterhaus, A., Sutter, G., Prajeeth, C. K., & Rimmelzwaan, G. F. (2023). A recombinant modified vaccinia virus Ankara expressing prME of tick-borne encephalitis virus affords mice full protection against TBEV infection. Frontiers in Immunology, 14, Article 1182963. https://doi.org/10.3389/fimmu.2023.1182963
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Kubinski, M., Beicht, J., Zdora, I., Saletti, G., Kircher, M., Petry-Gusmag, M., Steffen, I., Puff, C., Jung, K., Baumgärtner, W., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., & Prajeeth, C. K. (2023). Cross-reactive antibodies against Langat virus protect mice from lethal tick-borne encephalitis virus infection. Frontiers in Immunology, 14, Article 1134371. https://doi.org/10.3389/fimmu.2023.1134371
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Nair, N., Osterhaus, A., Rimmelzwaan, G., & Prajeeth, C. K. (2023). Rift Valley fever virus: infection, pathogenesis and host immune responses. Pathogens, 12(9), Article 1174. https://doi.org/10.3390/pathogens12091174
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Pilchová, V., Prajeeth, C. K., Jendrny, P., Twele, F., Meller, S., Pink, I., Volk, H. A., Osterhaus, A., von Köckritz-Blickwede, M., & Schulz, C. (2023). β-Propiolactone (BPL)-inactivation of SARS-Co-V-2: in vitro validation with focus on saliva from COVID-19 patients for scent dog training. In 32nd Annual Meeting of the Society of Virology: abstracts (P 267).
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Pilchová, V., Prajeeth, C. K., Jendrny, P., Twele, F., Meller, S., Pink, I., Fathi, A., Addo, M. M., Volk, H. A., Osterhaus, A., Köckritz-Blickwede, M. v., & Schulz, C. (2023). β-Propiolactone (BPL)-inactivation of SARS-Co-V-2: in vitro validation with focus on saliva from COVID-19 patients for scent dog training. Journal of Virological Methods, 317, 114733. https://doi.org/10.1016/j.jviromet.2023.114733
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Martin Ludlow, PhD

Guilfoyle, K., Mirolo, M., van, van der, Lombardo, M. S., Störk, T., Rimmelzwaan, G., Ludlow, M., & Osterhaus, A. (2025). Susceptibility of calf lung slice cultures to H5N1 influenza virus. Emerging Microbes & Infections, 14(1), Article 2432368. https://doi.org/10.1080/22221751.2024.2432368
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Kolbe, S. M., Guilfoyle, K., Reineking, W., van Amerongen, G., van der Net, G., Lockow, S., Baumgärtner, W., Ludlow, M., & Osterhaus, A. D. M. E. (2025). Syrian hamsters (Mesocricetus auratus) as an upper respiratory tract model for respiratory syncytial virus infection. Npj Viruses, 3, Article 2. https://doi.org/10.1038/s44298-024-00086-6
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Mirolo, M., Kühl, B., Roji, M. D., Rubio-García, A., Lima, V. A., Puff, C., Martina, B., Beineke, A., Wohlsein, P., Baumgärtner, W., Ludlow, M., & Osterhaus, A. (2025). Hepatovirus infections in juvenile seals from the North Sea. Npj Viruses, 3, Article 1. https://doi.org/10.1038/s44298-024-00084-8
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Gregor, K. M., Mirolo, M., Brandes, F., Jesse, S. T., Kaiser, F., Verspohl, J., Wölfl, S., Osterhaus, A. D. M. E., Baumgärtner, W., Ludlow, M., & Beineke, A. (2024). Fatal feline leukemia virus-associated enteritis in a wild Eurasian lynx (Lynx lynx) in Germany. Biology, 13(12), Article 997. https://doi.org/10.3390/biology13120997
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Hetterich, J., Mirolo, M., Kaiser, F., Ludlow, M., Reineking, W., Zdora, I., Hewicker-Trautwein, M., Osterhaus, A. D. M. E., & Pees, M. (2024). Concurrent detection of a papillomatous lesion and sequence reads corresponding to a member of the family Adintoviridae in a bell’s hinge-back tortoise (Kinixys belliana). Animals, 14(2), Article 247. https://doi.org/10.3390/ani14020247
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Kühl, B., Mirolo, M., Rubio-Garcìa, A., Wohlsein, P., Puff, C., Ludlow, M., Osterhaus, A., Baumgärtner, W., & Beineke, A. (2024). Phocines Hepatovirus: erster Nachweis bei Seehunden in Nordeuropäischen Gewässern. In 67. Jahrestagung der Fachgruppe Pathologie der Deutschen Veterinärmedizinischen Gesellschaft (P13). https://doi.org/10.1055/s-0044-1787379
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Mirolo, M., Roi, M. d. l., von Dörnberg, K., Kaiser, F., Fayyad, A., Puff, C., Voigt, U., Siebert, U., Ludlow, M., Baumgärtner, W., & Osterhaus, A. (2024). Umatilla virus in zoo-dwelling cape penguins with hepatitis, Germany. Emerging Infectious Diseases, 30(12), 2643–2646. https://doi.org/10.3201/eid3012.240498
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Pöpperl, P., Chludzinski, E., Stoff, M., Ludlow, M., Geffers, R., & Beineke, A. (2024). Hundeelend in der Titerplatte: In vitro-Infektion primärer Zielzellen des kaninen Staupevirus erlaubt Einblicke in Mechanismen der angeborenen Immunantwort. In Tierärztliche Praxis / K. Thieme. https://doi.org/10.1055/s-0044-1787336
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Waldock, J., Cox, R. J., Engelhardt, O. G., Ascough, S., Osterhaus, A., Rimmelzwaan, G. F., Ludlow, M., Tregoning, J. S., McDonald, J. U., Buchholz, U. J., Jeeninga, R. E., Sande, C., & Chiu, C. (2024). Inno4Vac workshop report part 2: RSV-controlled human infection model (CHIM) strain selection and immune assays for RSV CHIM studies, November 2021, MHRA, UK. Influenza and Other Respiratory Viruses, 18(10), Article e70013. https://doi.org/10.1111/irv.70013
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Wiese, L., Kolbe, S. M., Weber, M., Ludlow, M., & Christmann, M. (2024). Synthesis and biological evaluation of cleistocaltone A, an inhibitor of respiratory syncytial virus (RSV). Chemical Science, 15(26), 10121–10125. https://doi.org/10.1039/d4sc01897d
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