Publications

Nair, N., Friese, J., Wichgers Schreur, P. J., Osterhaus, A. D. M. E., Rimmelzwaan, G. F., & Prajeeth, C. K. (2026). Differential innate immune activation by wild-type and NSs-deficient RVFV strains in human blood monocytes. Emerging Microbes & Infections, 15(1), Article 2610855. https://doi.org/10.1080/22221751.2025.2610855
read more

Agac, A., Ludlow, M., Knittler, M.-C., Kandiyil, P. C., Saletti, G., Osterhaus, A. D. M. E., Meineke, R., & Rimmelzwaan, G. F. (2025). A contemporary strain of RSV activates primary human monocytes after abortive infection. Frontiers in Immunology, 16, Article 1699818. https://doi.org/10.3389/fimmu.2025.1699818
read more

Nair, N. (2025). Rift Valley fever virus infection in human PBMC — Characterisation of innate immune response and determining its role in virus dissemination. https://elib.tiho-hannover.de/receive/tiho_mods_00014755
read more

Nair, N., Wichgers Schreur, P. J., Osterhaus, A. D. M. E., Rimmelzwaan, G. F., & Chitappen Kandiyil, P. (2025). Characterization of innate immune responses induced by Rift Valley fever virus (RVFV) in human PBMCs. In 9th European Congress of Virology 2025: abstracts (PP 224).
read more

Schweitzer, F., Letoha, T., Osterhaus, A., & Prajeeth, C. K. (2025). Impact of tick-borne orthoflaviviruses infection on compact human brain endothelial barrier. International Journal of Molecular Sciences, 26(5), Article 2342. https://doi.org/10.3390/ijms26052342
read more

Schweitzer, F., Schröder, L.-J., Friedrichs, A., Gudi, V., Skripuletz, T., Steffen, I., Palus, M., Růžek, D., Osterhaus, A., & Prajeeth, C. K. (2025). Mosquito- and tick-borne orthoflaviviruses cross an in vitro endothelial-astrocyte barrier. Frontiers in Cellular and Infection Microbiology, 15, Article 1624636. https://doi.org/10.3389/fcimb.2025.1624636
read more

Kubinski, M., Beicht, J., Gerlach, T., Aregay, A., Osterhaus, A. D. M. E., Tscherne, A., Sutter, G., Prajeeth, C. K., & Rimmelzwaan, G. F. (2024). Immunity to tick-borne encephalitis virus NS3 protein induced with a recombinant modified vaccinia virus Ankara fails to afford mice protection against TBEV infection. Vaccines, 12(1), Article 105. https://doi.org/10.3390/vaccines12010105
read more

Leroux-Roels, I., Prajeeth, K. C., Aregay, A., Nair, N., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., Kardinahl, S., Pelz, S., Bauer, S., D’Onofrio, V., Alhatemi, A., Jacobs, B., De Boever, F., Porrez, S., Waerlop, G., Punt, C., Hendriks, B., von, van de, et al. (2024). Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against rift valley fever in healthy adults: a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial. The Lancet: Infectious Diseases, 24(11), 1245–1253. https://doi.org/10.1016/S1473-3099(24)00375-X
read more

Nair, N., Chitappen Kandiyil, P., & Rimmelzwaan, G. F. (2024). Innate immune responses induced by attenuated Rift Valley Fever Virus (RVFV) infection in human PBMC. In 17th Graduate School Day: 22/23 November 2024 : abstract book (Zoo T 07). 17th Graduate School Days, 22.11.2024 – 23.11.2024. Stiftung Tierärztliche Hochschule Hannover.
read more

Nair, N., Wichgers Schreur, P. J., Osterhaus, A. D. M. E., Rimmelzwaan, G. F., & Chittappen Kandiyil, P. (2024). Characterisation of innate immune responses induced by the Rift Valley Fever Virus (RVFV) in humans. International One Health Symposium 2024, 17.10.2024 - 19.10.2024.
read more

Hennig-Pauka, I., Kähl, S., Ludlow, M., Strutzberg-Minder, K., & Nicolaisen, T. J. (2026). Atemwegsprobleme und plötzliche Todesfälle bei Mastschweinen: es ist nicht immer, wonach es aussieht. In R. Rackwitz & U. Truyen (eds.), Leipziger Tierärztekongress 2026: Tagungsband 3. https://images.leipziger-messe.de/epaper/tieraerztekongress/tagungsband3
read more

Kühl, B., Mirolo, M., Lima, V. A., Rubio-Garcia, A., Ludlow, M., Osterhaus, A. D. M. E., Baumgärtner, W., Beineke, A., & Wohlsein, P. (2026). Immunohistochemical demonstration of phocine herpesvirus-1 antigen in harbour seals (Phoca vitulina) of the North Sea. Journal of Comparative Pathology, 224, 10–15. https://doi.org/10.1016/j.jcpa.2026.01.005
read more

Pöpperl, P., Chludzinski, E., Stoff, M., Geffers, R., Ludlow, M., & Beineke, A. (2026). Attenuation of canine distemper virus leads to a potent antiviral innate immune response with restricted infection of alveolar macrophages. Journal of Virology, 100(1), Article e0176125. https://doi.org/10.1128/jvi.01761-25
read more

Agac, A., Ludlow, M., Knittler, M.-C., Kandiyil, P. C., Saletti, G., Osterhaus, A. D. M. E., Meineke, R., & Rimmelzwaan, G. F. (2025). A contemporary strain of RSV activates primary human monocytes after abortive infection. Frontiers in Immunology, 16, Article 1699818. https://doi.org/10.3389/fimmu.2025.1699818
read more

Guilfoyle, K., Mirolo, M., van, van der, Lombardo, M. S., Störk, T., Rimmelzwaan, G., Ludlow, M., & Osterhaus, A. (2025). Susceptibility of calf lung slice cultures to H5N1 influenza virus. Emerging Microbes & Infections, 14(1), Article 2432368. https://doi.org/10.1080/22221751.2024.2432368
read more

Guilfoyle, K., Mirolo, M., de Waal, L., van Amerongen, G., van der Net, G., Störk, T., Lombardo, M. S., Baumgärtner, W., Bjarnason, Á., Jóhannsdóttir, H. B., Rimmelzwaan, G. F., Ludlow, M., & Osterhaus, A. D. M. E. (2025). Highly pathogenic avian influenza virus A/H5N1 subclade 2.3.4.4 b isolated from a European grey seal (Halichoerus grypus) is highly virulent in ferrets. The Journal of Infectious Diseases, 232(6), e886–e896. https://doi.org/10.1093/infdis/jiaf348
read more

Kolbe, S. M., Guilfoyle, K., Reineking, W., van Amerongen, G., van der Net, G., Lockow, S., Baumgärtner, W., Ludlow, M., & Osterhaus, A. D. M. E. (2025). Syrian hamsters (Mesocricetus auratus) as an upper respiratory tract model for respiratory syncytial virus infection. In 9th European Congress of Virology 2025: abstracts (PP 062).
read more

Kolbe, S. M., Guilfoyle, K., Reineking, W., van Amerongen, G., van der Net, G., Lockow, S., Baumgärtner, W., Ludlow, M., & Osterhaus, A. D. M. E. (2025). Syrian hamsters (Mesocricetus auratus) as an upper respiratory tract model for respiratory syncytial virus infection. Npj Viruses, 3, Article 2. https://doi.org/10.1038/s44298-024-00086-6
read more

Kühl, B., Mirolo, M., Roji, M. D., Lima, V. A., Pohlmann, A., Harder, T., Ahrens, A. K., Baechlein, C., Kleinschmidt, S., Hartmann, D., Kammeyer, P., Wöhlke, A., Warmann, T., Herms, L., Runge, M., Rubio-Garcia, A., Kramer, K., Meinfelder, U., Rosenberger, T., et al. (2025). Investigation of potential viral etiology and associated pathogenesis in disease syndromes of unknown cause in wildlife and marine mammals. In 18th Graduate School Day: 21 November 2025 : abstract book (ZSN T 07). Stiftung Tierärztliche Hochschule Hannover.
read more

Maschmeier, A. L., Mirolo, M., Ludlow, M., Osterhaus, A., Krieg, K., Wenzel, F., Su, A., Becher, P., & Beineke, A. (2025). Virusinfektionen von respiratorischen Organoiden aus adulten Stammzellen von Hunden (Canis lupus familiaris) und Frettchen (Mustela putorius furo). In 68. Jahrestagung der Fachgruppe Pathologie der Deutschen Veterinärmedizinischen Gesellschaft (P05). https://doi.org/10.1055/s-0045-1808585
read more