The Institute for Biochemistry at the University of Veterinary Medicine Hannover was founded in 1965 with Prof. Niesar as the first director and head of the institute for Physiological Chemistry. The institute's office and laboratory rooms were initially located in the Physiological Institute building on the Bischofsholer Damm campus. As successor to Prof. Niesar, Prof. Jürgen Schole became the new director and head of the institute in 1969.
In 1977 the Institute for Physiological Chemistry moved into new office and laboratory rooms on two floors in Building 218 on the newly built campus on Bünteweg in the Kirchrode district. The staff of the institute at the new location included three professors, five research assistants, seven technical assistants and several doctoral students. In addition to the courses in biochemistry for veterinary students, the main research focus of the institute included the investigation of the metabolic pathways of carbohydrates and fats in animals. After the retirement of Prof. Schole (Prof. em.), Prof. Hans-Peter Sallmann took over the management of the institute from 1992 to 1997.
In 1997 the biochemist and cell biologist Prof. Dr. Hassan Y. Naim accepted the call of the University of Veterinary Medicine Hannover as the new director and head of the institute. The research interests now expanded to the investigation of the molecular mechanisms of protein and membrane transport in the healthy body and in diseases. The research focuses on gastrointestinal diseases, lysosomal storage diseases and prostate cancer. The teaching activities have also been expanded to include the entire curriculum of compulsory and elective courses in biochemistry for veterinary students. Furthermore, from now on, teaching and training events in cell and molecular biology as well as in pathobiochemistry were offered for students of biology and biochemistry.
In 2004 Prof. Sallmann retired and the biotechnologist Prof. Bernd Otto from the Fraunhofer Institute became an associate member of the institute. Prof. Otto held the chair for biotechnology and molecular biology, which was founded by the state of Lower Saxony. Until his retirement in 2010, he participated in the teaching and training events of the Institute for Physiological Chemistry.
In 2010, Dr. Maren von Köckritz-Blickwede became a new employee at the institute. She had already gained several years of professional experience in research on infectious diseases at the University of California in San Diego and at the Helmholtz Center for Infection Research in Braunschweig. Dr. von Köckritz Blickwede, together with Prof. Naim, initiated new research projects to investigate the biochemical basis of infections and the immune system. The focus is laid here on the investigation of the so-called extracellular traps (ETs) of phagocytic cells. These projects established the new research focus on infection biochemistry within the Department of Biochemistry. In February 2015, Dr. von Köckritz-Blickwede accepted a W2 professorship at the University of Veterinary Medicine in Hanover and became head of the new Infection Biochemistry Working Group at the Institute of Biochemistry.