Publications

Mahmoud, S. A., Mohamed, A. O. M., von Köckritz-Blickwede, M., & Naim, H. Y. (2026). Differential trafficking phenotypes of NPC1 mutant proteins reveal distinct cholesterol accumulation profiles. Journal of Inherited Metabolic Disease, 49(3), Article e70186. https://doi.org/10.1002/jimd.70186
read more

Tannous, S., Hoter, A., Das, A. M., & Naim, H. Y. (2026). Lipid-dependent uptake of pegunigalsidase alfa across cell types: implications for multiorgan treatment. In Molecular genetics and metabolism (109640). Elsevier BV. https://doi.org/10.1016/j.ymgme.2025.109640
read more

Hoter, A., Das, A. M., & Naim, H. Y. (2025). Cellular uptake and function of recombinant pegunigalsidase alfa in fibroblasts from Fabry patients. In Molecular genetics and metabolism (108771). Elsevier BV. https://doi.org/10.1016/j.ymgme.2024.108771
read more

Hoter, A., Tannous, S., Das, A. M., & Naim, H. Y. (2025). Membrane lipid composition regulates cellular binding and uptake of pegunigalsidase alfa across diverse cell types, including fabry fibroblasts: possible implications for multiorgan treatment. 15th International Congress of Inborn Errors of Metabolism (ICIEM2025), Kyoto (Japan), 02.-06.09.2025.
read more

Lynch-Miller, M., Lockow, S., Dümmer, K., Henneck, T., Olmer, R., Jaboreck, M.-C., Mergani, A. O., Wandrey, M., Branitzki-Heinemann, K., Brogden, G., Naim, H. Y., Martin, U., Schulz, C., Talbot, S. R., Meurer, M., Baumgärtner, W., & von Köckritz-Blickwede, M. (2025). Characterization of 3D human pulmonary epithelial model morphology and oxygen status under normoxia and hypoxia. Biochimica et Biophysica Acta: Molecular Cell Research, 1872(6), Article 119980. https://doi.org/10.1016/j.bbamcr.2025.119980
read more

Tannous, S., Husein, D. M., & Naim, H. Y. (2025). Congenital sucrase-isomaltase mutations worsen IBS-linked V15F dysfunction and trafficking. Gut: The Journal of the British Society of Gastroenterology. https://doi.org/10.1136/gutjnl-2025-336813
read more

Tannous, S., & Naim, H. Y. (2025). Sucrase-isomaltase gene variants in irritable bowel syndrome: impact on protein trafficking and enzyme function. 15th International Congress of Inborn Errors of Metabolism (ICIEM2025), Kyoto (Japan), 02.-06.09.2025.
read more

Torices, L., Bonfiglio, F., Esteban-Blanco, C., Zamfir-Taranu, A., Naim, H. Y., D’Amato, M., & D’Amato, M. (2025). Domain-specific effects of sucrase-isomaltase genotype in irritable bowel syndrome. Gastroenterology, 169(2), 346–348. https://doi.org/10.1053/j.gastro.2025.01.242
read more

Zamfir-Taranu, A., Löscher, B.-S., Carbone, F., Hoter, A., Esteban Blanco, C., Bozzarelli, I., Torices, L., Routhiaux, K., Houte, K. V. d., Bonfiglio, F., Mayr, G., Corsetti, M., Naim, H. Y., Franke, A., Tack, J., & D’Amato, M. (2025). Functional variation in human CAZyme genes in relation to the efficacy of a carbohydrate-restricted diet in IBS patients. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, 23(7), 1228–1237. https://doi.org/10.1016/j.cgh.2024.09.004
read more

Abi Sleiman, M., Younes, M., Hajj, R., Salameh, T., Abi Rached, S., Abi Younes, R., Daoud, L., Doumiati, J. L., Frem, F., Ishak, R., Medawar, C., Naim, H. Y., & Rizk, S. (2024). Urtica dioica: anticancer properties and other systemic health benefits from in vitro to clinical trials. International Journal of Molecular Sciences, 25(13), Article 7501. https://doi.org/10.3390/ijms25137501
read more