Publikationen W. Löscher
Balta, D., Varghese, A., Prieto Huarcaya, S., Di Spiezio, A., Marques, A. R. A., Akdaş, E. Y., Tabakacilar, D., Drobny, A., Werner, C., Xiang, W., Mächtel, R., Dobert, J. P., Fejtova, A., Richter, F., Küspert, M., Arnold, P., Saftig, P., & Zunke, F. (2025). Recombinant cathepsins B and L promote α-synuclein clearance and restore lysosomal function in human and murine models with α-synuclein pathology. Molecular Neurodegeneration, 20, Article 95. https://doi.org/10.1186/s13024-025-00886-1
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Drath, I., Richter, F., & Feja, M. (2025). Nose-to-brain drug delivery: from bench to bedside. Translational Neurodegeneration, 14, Article 23. https://doi.org/10.1186/s40035-025-00481-w
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Feja, M., Drath, I., Weiß, S., Ewe, A., Gericke, B., Outeiro, T. F., Stefanis, L., Aigner, A., & Richter, F. (2025). Nose-to-brain siRNA delivery by PEI/PPI-based nanoparticles reduces α-synuclein expression in a Parkinson’s disease mouse model. Molecular Therapy: Nucleic Acids, 36(3), Article 102671. https://doi.org/10.1016/j.omtn.2025.102671
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Hartke, A.-S., Schreiber, C. S., Lau, K., Wiesweg, I., Waltl, I., Kalinke, U., Richter, F., & Käufer, C. (2025). Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins. Neurobiology of Disease, 205, Article 106773. https://doi.org/10.1016/j.nbd.2024.106773
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Höllerhage, M., Duan, L., Chua, O. W. H., Moebius, C., Bothe, S. H., Losse, K., Kotzur, R., Lau, K., Hopfner, F., Richter, F., Wahl-Schott, C., Bickle, M., & Höglinger, G. U. (2025). A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model. Translational Neurodegeneration, 14(1), Article 27. https://doi.org/10.1186/s40035-025-00486-5
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Käufer, C., Stanojlović, M., Schidlitzki, A., Bonsberger, J., Storch, A., & Richter, F. (2025). Alterations in non-REM sleep and EEG spectra precede REM-sleep deficits in a model of synucleinopathy. Journal of Parkinson’s Disease: JPD, 15(2), 311–328. https://doi.org/10.1177/1877718X241310723
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Lai, T. T., Xiang, W., Stanojlovic, M., Käufer, C., Feja, M., Lau, K., Zunke, F., & Richter, F. (2025). The basolateral amygdala and striatum propagate alpha-synuclein pathology causing increased fear response in a Parkinson’s disease model. Brain, Behavior, and Immunity: An International Journal, 128, 469–486. https://doi.org/10.1016/j.bbi.2025.04.025
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Schreiber, C. S., Ramil, L. N., Bieligk, J., Meineke, R., Käufer, C., & Richter, F. (2025). Intravenous SARS-CoV-2 Spike protein induces neuroinflammation and alpha-synuclein accumulation in brain regions relevant to Parkinson’s disease. Brain, Behavior, and Immunity: An International Journal, 129, 102–123. https://doi.org/10.1016/j.bbi.2025.05.021
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Weiß, S., Feja, M., Drath, I., Ewe, A., Aigner, A., & Richter Assencio, F. (2025). Nanoparticle-mediated RNA interference to regulate alpha-synuclein expression in an in vitro Parkinson’s disease model. In 10th German Pharm-Tox Summit 2025 (P096). https://doi.org/10.1007/s00210-025-03881-x
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Zalpanow, D., Feja, M., Kotzur, R., Stelz, S., Garmer, M., Moreno, I., Prades, R., & Richter, F. (2025). Characterization of neuroprotective effects mediated by prolyl endopeptidase: inhibitory compounds for the treatment of Parkinsons disease. In 10th German Pharm-Tox Summit 2025 (P080). https://doi.org/10.1007/s00210-025-03881-x
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