Publikationen W. Löscher

Drath, I., Richter, F., & Feja, M. (2025). Nose-to-brain drug delivery: from bench to bedside. Translational Neurodegeneration, 14, Article 23. https://doi.org/10.1186/s40035-025-00481-w
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Feja, M., Drath, I., Weiß, S., Ewe, A., Gericke, B., Outeiro, T. F., Stefanis, L., Aigner, A., & Richter, F. (2025). Nose-to-brain siRNA delivery by PEI/PPI-based nanoparticles reduces α-synuclein expression in a Parkinson’s disease mouse model. Molecular Therapy: Nucleic Acids, 36(3), Article 102671. https://doi.org/10.1016/j.omtn.2025.102671
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Hartke, A.-S., Schreiber, C. S., Lau, K., Wiesweg, I., Waltl, I., Kalinke, U., Richter, F., & Käufer, C. (2025). Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins. Neurobiology of Disease, 205, Article 106773. https://doi.org/10.1016/j.nbd.2024.106773
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Höllerhage, M., Duan, L., Chua, O. W. H., Moebius, C., Bothe, S. H., Losse, K., Kotzur, R., Lau, K., Hopfner, F., Richter, F., Wahl-Schott, C., Bickle, M., & Höglinger, G. U. (2025). A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model. Translational Neurodegeneration, 14(1), Article 27. https://doi.org/10.1186/s40035-025-00486-5
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Käufer, C., Stanojlović, M., Schidlitzki, A., Bonsberger, J., Storch, A., & Richter, F. (2025). Alterations in non-REM sleep and EEG spectra precede REM-sleep deficits in a model of synucleinopathy. Journal of Parkinson’s Disease: JPD, 15(2), 311–328. https://doi.org/10.1177/1877718X241310723
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Lai, T. T., Xiang, W., Stanojlovic, M., Käufer, C., Feja, M., Lau, K., Zunke, F., & Richter, F. (2025). The basolateral amygdala and striatum propagate alpha-synuclein pathology causing increased fear response in a Parkinson’s disease model. Brain, Behavior, and Immunity: An International Journal, 128, 469–486. https://doi.org/10.1016/j.bbi.2025.04.025
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Schreiber, C. S., Ramil, L. N., Bieligk, J., Meineke, R., Käufer, C., & Richter, F. (2025). Intravenous SARS-CoV-2 Spike protein induces neuroinflammation and alpha-synuclein accumulation in brain regions relevant to Parkinson’s disease. Brain, Behavior, and Immunity: An International Journal, 129, 102–123. https://doi.org/10.1016/j.bbi.2025.05.021
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Weiß, S., Feja, M., Drath, I., Ewe, A., Aigner, A., & Richter Assencio, F. (2025). Nanoparticle-mediated RNA interference to regulate alpha-synuclein expression in an in vitro Parkinson’s disease model. In 10th German Pharm-Tox Summit 2025 (P096). https://doi.org/10.1007/s00210-025-03881-x
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Zalpanow, D., Feja, M., Kotzur, R., Stelz, S., Garmer, M., Moreno, I., Prades, R., & Richter, F. (2025). Characterization of neuroprotective effects mediated by prolyl endopeptidase: inhibitory compounds for the treatment of Parkinsons disease. In 10th German Pharm-Tox Summit 2025 (P080). https://doi.org/10.1007/s00210-025-03881-x
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Drath, I., Feja, M., Gericke, B., Weiß, S., Ewe, A., Aigner, A., & Richter, F. (2024). Nanoparticle-based nose-to-brain delivery of small RNA mediates downregulation of alpha-synuclein in a Parkinson’s disease mouse model. In AD/PD 2024 posters. https://cslide.ctimeetingtech.com/adpd24/attendee
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