Publications

2020

 

D.L. Lindenwald, J.T. Monteiro, S. Rautenschlein, J. Meens, K. Jung, S.C. Becker, B. Lepenies: Ovine C-type Lectin Receptor hFc-fusion Protein Library - A Novel Platform to Screen for Host-Pathogen Interactions. Vet. Immunol. Immunopathol. 2020; 224:110047.

 

R.F. Roller, A. Malik, M.A. Carillo, M. Garg, A. Rella, M.K. Raulf, B. Lepenies, P.H. Seeberger, D.V. Silva: Semisynthesis of Functional Glycosylphosphatidylinositol-Anchored Proteins. Angew. Chem. Int. Ed. Engl. 2020; 10.1002.

 

A. Malik, F. Steinbeis, M.A. Carillo, P.H. Seeberger, B. Lepenies*, D. Varón Silva*: Immunological Evaluation of Synthetic Glycosylphosphatidylinositol Glycoconjugates as Vaccine Candidates against Malaria. ACS Chem. Biol. 2020: 15(1): 171-78.

 

 

2019

 

K. Bode, F. Bujupi, C. Link, T. Hein, S. Zimmermann, D. Peiris, V. Jaquet, B. Lepenies, H. Weyd, P.H. Krammer: Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2. Cell Rep. 2019, 29(13): 4435-46.

 

M. Prado Acosta, B. Lepenies*: Bacterial glycans and their interactions with lectins in the innate immune system. Biochem. Soc Trans. 2019, 47(6):1569-1579.

 

B. Lepenies*, R. Lang*: Editorial: Lectins and Their Ligands in Shaping Immune Responses. Front. Immunol.2019, 10, 2379.

 

T.J. Kottom, D.M. Hebrink, J.T. Monteiro, B. Lepenies, E.M. Carmona, M. Wuethrich, L.D. Santo Dias, A.H. Limper: Myeloid C-type lectin receptors that recognize fungal mannans interact with Pneumocystis organisms and major surface glycoprotein. J. Med. Microbiol. 2019, 68(11): 1649-54. 

 

M.K. Raulf, T. Johannssen, S. Matthiesen, K. Neumann, S. Hachenberg, S. Mayer-Lambertz, F. Steinbeis, J. Hegermann, PH. Seeberger, W. Baumgärtner, C. Strube, J. Ruland, B. Lepenies*: The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development. Cell Rep. 2019, 28(1): 30-38.

 

L.M. Roesner, M. Ernst, W. Chen, G. Begemann, P. Kienlin, M.K. Raulf, B. Lepenies, T Werfel: Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2. Sci. Rep. 2019, 9: 11210.

 

M. Malamud, P. Carasi, M.H. Assandri, T. Freire, B. Lepenies*, MLA Serradell*: S-Layer Glycoprotein From Lactobacillus kefiri Exerts Its Immunostimulatory Activity Through Glycan Recognition by Mincle. Front Immunol. 2019, 10: 1422.

 

M. Prado Acosta, E.M. Geoghegan, S. Ruzal, B. Lepenies, M. Kielian, M.G. Martinez*: Surface Layer Proteins of Lactobacillus acidophilus Block Alphavirus and Flavivirus Infection via DC-SIGN Interaction. Front. Microbiol. 2019, 10: 810

 

J.T. Monteiro, K. Schön, T. Ebbecke, R. Goethe, J. Ruland, W. Baumgärtner, S.C. Becker*, B. Lepenies*: The CARD9-Associated C-Type Lectin, Mincle, Recognizes La Crosse Virus (LACV) but Plays a Limited Role in Early Antiviral Responses against LACV. Viruses 2019, 11(3): pii: E303.

 

R. Heß, M. Storcksdieck gen. Bonsmann, D. Lapuente, A. Maaske, C. Kirschning, J. Ruland, B. Lepenies, D. Hannaman, M. Tenbusch*, K. Überla: Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination. Viruses 2019, 11(2): pii: E153.

 

Geissner, A. Reinhardt, C. Rademacher, T. Johannssen, J.T. Monteiro, B. Lepenies, M. Thépaut, F. Fieschi, J. Mrázková, M. Wimmerova, F. Schuhmacher, S. Götze, D. Grünstein, X. Guo, H.S. Hahm, J. Kandasamy, D. Leonori, C.E. Martin, S.G. Parameswarappa, S. Pasari, M.K. Schlegel, H. Tanaka, G. Xiao, Y. Yang, C.L. Pereira, C. Anish, P.H. Seeberger*: A microbe-focused glycan array screening platform. Proc. Natl. Acad. Sci. U.S.A. 2019, 116(6): 1958-67.

 

 

2018

 

T. Imai, T. Matsumura, S. Mayer-Lambertz, C.A. Wells, E. Ishikawa, S.K. Butcher, T.C. Barnett, M.J. Walker, A. Imamura, H. Ishida, T. Ikebe, T. Miyamoto, M. Ato, S. Ohga, B. Lepenies, N.M. van Sorge, S. Yamasaki: Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection. Proc. Natl. Acad. Sci. U.S.A. 2018, 115(45): 10662-71.

 

C.D. Shanthamurthy, P. Jain, S. Yehuda, J.T. Monteiro, S. Leviatan Ben-Arye, B. Subramani, B. Lepenies, V. Padler-Karavani, R. Kikkeri: ABO Antigens Active Tri- And Disaccharides Microarray to Evaluate C-type Lectin Receptor Binding Preferences. Sci Rep. 2018;8(1):6603.

 

F. Ota, T. Hirayama, Y. Kizuka, Y. Yamaguchi, R. Fujinawa, M. Nagata, H.S. Ismanto, B. Lepenies, J. Aretz, C. Rademacher, P.H. Seeberger, T. Angata, S. Kitazume, K. Yoshida, T. Betsuyaku, K. Kida, S. Yamasaki, N. Taniguchi: High Affinity Sugar Ligands of C-type Lectin Receptor Langerin. Biochim Biophys Acta. 2018:1862(7):1592-1601.

 

M. Gade, C. Alex, S.L. Ben-Arye, J.T. Monteiro, S. Yehuda, B. Lepenies, V. Padler Karavani, R.V. Kikkeri: Microarray Analysis of Oligosaccharide-Mediated Multivalent Carbohydrate-Protein Interactions and Their Heterogeneity. Chembiochem. 2018:19(11):1170-77.

 

N. Zimara, M. Chanyalew, A. Aseffa, G. van Zandbergen, B. Lepenies, M. Schmid, R. Weiss, A. Rascle, A.K. Wege, J. Jantsch, V. Schatz, G.D. Brown, U. Ritter: Dectin-1 Positive Dendritic Cells Expand After Infection With Leishmania major Parasites and Represent Promising Targets for Vaccine Development. Front Immunol. 2018;9:263.

 

S. Mayer, R. Moeller, J.T. Monteiro, K. Ellrott, C. Josenhans, B. Lepenies: C-Type Lectin Receptor (CLR)-Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates. Front Immunol. 2018;9:213.

 

J. Kruppa, B. Lepenies, K. Jung: A Genetic Algorithm for Simulating Correlated Binary Data From Biomedical Research. Comput Biol Med. 2018;92:1-8.

 

 

2017

 

G. Artigas, J.T. Monteiro, H. Hinou, S.I. Nishimura, B. Lepenies, F. Garcia-Martin: Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile Toward Macrophage Galactose-Type Lectin (MGL) Orthologs. J Med Chem. 2017;60(21):9012-9021.

 

J. Schick, P. Etschel, R. Bailo, L. Ott, A. Bhatt, B. Lepenies, C. Kirschning, A. Burkovski, R. Lang: Toll-Like Receptor 2 and Mincle Cooperatively Sense Corynebacterial Cell Wall Glycolipids. Infect Immun. 2017;85(7). pii: e00075-17.

 

J.T. Monteiro, B. Lepenies: Myeloid C-Type Lectin Receptors in Viral Recognition and Antiviral Immunity. Viruses. 2017;9(3). pii: E59.

 

T.J. Kottom, D.M. Hebrink, P.E. Jenson, V. Nandakumar, M. Wüthrich, H. Wang, B. Klein,  S. Yamasaki, B. Lepenies, A.H. Limper: The Interaction of Pneumocystis With the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense Against Infection. J. Immunol. 2017;198(9):3515-3525.

 

A.V. Kostarnoy, P.G. Gancheva, B. Lepenies, A.l. Tukhvatulin, A.S. Dzharullaeva, N.B. Polyakov, D.A. Grumov, D.A. Egorova, A.Y. Kulibin, M.A. Bobrov, E.A. Malolina, P.A. Zykin, A.l. Soloviev, E. Riabenko, D.V. Maltseva, D.A. Sakharov, A.G. Tonevitsky, L.V. Verkhovskaya, D.Y. Logunov, B.S. Naroditsky, A.L. Gintsburg: Receptor Mincle Promotes Skin Allergies and Is Capable of Recognizing Cholesterol Sulfate. <//span>Proc Natl Acad Sci U S A. 2017;114(13):E2758-E2765.

 

T. Johannssen, B. Lepenies*: Glycan-based cell targeting to modulate immune responses. Trends Biotechnol. 2017:35(4):334-46.

 

T.J. Kottom, D.M. Hebrink, P.E. Jenson, M. Wüthrich, H. Wang, B. Klein, S. Yamasaki, B. Lepenies, A.H. Limper*: The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense Against Infection. J. Immunol. 2017:198(9):3515-25.

 

A.V. Kostarnoy*, P.G. Gancheva, B. Lepenies, A.I. Tukhvatulin, A.S Dzharullaeva, N.B. Polyakov, D.A. Grumov, D.A. Egorova, A.Y. Kulibin, M.A. Bobrov, E.A. Malolina, P.A. Zykin, A.I. Soloviev, E. Riabenko, D.V. Maltseva, D.A. Sakharov, A. Tonevitsky, L.V. Verkhovskaya, D.Y. Logunov, B.S. Naroditsky, A.L. Gintsburg: The receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate. Proc. Natl. Acad. Sci. U.S.A. 2017:114(13):E2758-65.

 

S. Mayer, M.-K. Raulf, B. Lepenies*: C‑type lectins: their network and roles in pathogen recognition and immunity. Histochem. Cell Biol. 2017: 147(2), 223-37.

 

C. Gao, R. Fujinawa, T. Yoshida, M. Ueno, F. Ota, Y. Kizuka, T. Hirayama, H. Korekane, S. Kitazume, T. Maeno, K. Ohtsubo, K. Yoshida, Y. Yamaguchi, B. Lepenies, J. Aretz, C. Rademacher, H. Kabata, A. Hegab, P.H. Seeberger, T. Betsuyaku, K. Kida, N. Taniguchi*: A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models. Am. J. Physiol.-Lung Cell. Mol. Physiol. 2017: 312(2), L268-76.

 

A. Troegeler, I. Mercier, C. Cougoule, D. Pietretti, A. Colom, C. Duval, T.P. Vu Manh, F. Capilla, R. Poincloux, K. Pingris, J. Nigou, J. Rademann, M. Dalod, F.A. Verreck, T. Al Saati, G. Lugo-Villarino, B. Lepenies, D. Hudrisier, O. Neyrolles*: C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 2017: 114(4), E540-49.

 

 

2016

 

H. Bavireddi, R.V. Murthy, M. Gade, S. Sangabathuni, P.M. Chaudhari, C. Alex, B. Lepenies, R. Kikkeri*: Understanding carbohydrate–protein interactions using homologous supramolecular chiral Ru(II)-glyconanoclusters. Nanoscale 2016: 8(47), 19696-702.

 

K. Brzezicka, U. Vogel, S. Serna, T. Johannssen, B. Lepenies*, N.-C. Reichardt*: Influence of core β-1,2-xylosylation on glycoprotein recognition by murine C-type lectin receptors and its impact on dendritic cell targeting. ACS Chem. Biol. 2016: 11(8), 2347-56.

 

A. Huber, R.S. Kallerup, H. Franzyk, K.S. Korsholm, B. Lepenies, D. Christensen, C. Foged, R. Lang*: Trehalose-diester glycolipids are superior to monoesters in binding to Mincle, activation of macrophages in vitro, and adjuvant activity in vivo. Innate Immun. 2016: 22(6), 405-18.

 

C.-H. Lai, J. Hütter, C.-W. Hsu, H. Tanaka, S. Varela-Aramburu, L. De Cola, B. Lepenies*, P.H. Seeberger*: Analysis of carbohydrate-carbohydrate interactions using sugar-functionalized silicon nanoparticles for cell imaging. Nano Lett. 2016: 16(1), 807-11.

 

 

2015

 

C.N. LaRock, S. Döhrmann, J. Todd, R. Corriden, J. Olson, T. Johannssen, B. Lepenies, R.L Gallo, P. Ghosh, V. Nizet*: Group A streptococcal M1 protein sequesters cathelicidin to evade innate immune killing. Cell Host Microbe 2015: 18(4), 471-77.

 

J. Ostrop, K. Jozefowski, S. Zimmermann, K. Hofmann, E. Strasser, B. Lepenies, R. Lang*: Contribution of MINCLE-SYK signaling to activation of primary human antigen-presenting cells by mycobacterial cord factor and the novel adjuvant TDB. J. Immunol. 2015: 195(5), 2417-28. 

 

E. Zacco, J. Hütter, J.L. Heier, J. Mortier, P.H. Seeberger, B. Lepenies, B. Koksch*: Towards a tailored presentation of ligands: coiled coil-based glycopeptides for ASGPR targeting. ACS Chem. Biol. 2015: 10(9), 2065-72.

 

K. Täuber, B. Lepenies, J. Yuan*: Polyvinylpyridinium-type gradient porous membranes – synthesis, actuation and intrinsic cell growth inhibition. Polym. Chem. 2015: 6, 4855-58.

 

O. Redy-Keisar, K. Huth, U. Vogel, B. Lepenies, P.H. Seeberger, R. Haag, D. Shabat*: Enhancement of fluorescent properties of near-infrared dyes using clickable oligoglycerol dendrons. Org. Biomol. Chem. 2015: 13(16), 4727-32.

 

Y.L. Lightfoot, K. Selle, T. Yang, Y.J. Goh, B. Sahay, M. Zadeh, J.L. Owen, N. Colliou, E. Li, T. Johannssen, T. Ganguly, B. Lepenies, T.R. Klaenhammer, M. Mohamadzadeh*: C-type lectin receptor SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis. EMBO J. 2015: 34(7), 881-95.

 

A. Rabes, S. Zimmermann, K. Reppe, R. Lang, P.H. Seeberger, N. Suttorp, M. Witzenrath, B. Lepenies*, B. Opitz*: The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response. PLOS One 2015: 10(2): e0117022.

 

T. Johannssen, B. Lepenies*: Identification and Characterization of Carbohydrate-Based Adjuvants. Methods Mol. Biol. 2015; 1331: 173-87.

 

S. Zimmermann, B. Lepenies*: Glycans as Vaccine Antigens and Adjuvants: Immunological Considerations. Methods Mol. Biol. 2015; 1331: 11-26.

 

J. Hütter, B. Lepenies*: Carbohydrate-Based Vaccines: An Overview. Methods Mol. Biol. 2015; 1331: 1-10.

 

 

2014

 

H. Schoenen, A. Huber, N. Sonda, S. Zimmermann, J. Jantsch, B. Lepenies, V. Bronte, R. Lang*: Differential control of Mincle-dependent cord factor recognition and macrophage responses by the transcription factors C/EBPβ and HIF1α. J. Immunol. 2014: 193(7), 3664-75.

 

J. Hütter, M. Eriksson, T. Johannssen, R. Klopfleisch, D. von Smolinski,  A.D. Gruber, P.H. Seeberger, B. Lepenies*: Role of the C-type lectin receptors MCL and DCIR in experimental colitis. PLOS One 2014: 9(7): e103281.

 

N.M. van Sorge, J.N. Cole, K. Kuipers, A. Henningham, R.K. Aziz, A. Kasirer-Friede, L. Lin, E.T. Berends, M.R. Davies, G. Dougan, F. Zhang, S. Dahesh, L. Shaw, J. Gin, M. Cunningham, J.A. Merriman, J. Hütter, B. Lepenies, S.H.M. Rooijakkers, R. Malley, M.J. Walker, S.J. Shattil, P.M. Schlievert, B. Choudhury, V. Nizet*: Genetics and virulence role of the classical Group A Streptococcus Lancefield antigen. Cell Host Microbe 2014: 15(6), 729-40.

 

M. Eriksson, S. Serna, M. Maglinao, M.K. Schlegel, P.H. Seeberger, N.C. Reichardt*, B. Lepenies*: Biological evaluation of multivalent Lewis X-MGL-1 interactions. ChemBioChem 2014: 15(6), 844-51.

 

S.M. Miltsch, P.H. Seeberger, B. Lepenies*: The C-type lectin-like domain containing proteins Clec-39 and Clec-49 are crucial for Caenorhabditis elegans immunity against Serratia marcescens infection. Dev. Comp. Immunol. 2014: 45(1), 67-73.

 

M. Maglinao, M. Eriksson, M.K. Schlegel, S. Zimmermann, T. Johannssen, S. Götze, P.H. Seeberger, B. Lepenies*: A platform to screen for C-type lectin receptor-binding carbohydrates and their potential for cell-specific targeting and immune modulation. J. Control. Release. 2014: 175, 36-42.

 

B. Lepenies*, P.H. Seeberger*: Simply better glycoproteins. Nat. Biotechnol. 2014, 32(5): 443-45.

 

 

2013

 

M. Eriksson, T. Johannssen, D. von Smolinski, A.D. Gruber, P.H. Seeberger, B. Lepenies*: The C-type lectin receptor SIGNR3 binds to fungi present in commensal microbiota and influences immune regulation in experimental colitis. Front. Immunol. 2013: 4, 196.

 

M. Maglinao, R. Klopfleisch, P. Seeberger, B. Lepenies*: The C-type lectin receptor DCIR is crucial for the development of experimental cerebral malaria. J. Immunol. 2013: 191(5), 2551-59.

 

K. Shirato, C. Gao, F. Ota, T. Angata, H. Shogomori, K. Ohtsubo, K. Yoshida, B. Lepenies, N. Taniguchi*: Flagellin/Toll-like receptor 5 response was specifically attenuated by keratan sulfate disaccharide via decreased EGFR phosphorylation in normal human bronchial epithelial cells. BBRC 2013: 435(3): 460-65.

 

N. Karton-Lifshin, U. Vogel, E. Sella, P.H. Seeberger, D. Shabat*, B. Lepenies*: Enzyme mediated nutrient release: glucose-precursor activation by β-galactosidase to induce bacterial growth. Org. Biomol. Chem. 2013: 11(17): 2903-10.

 

J. Hütter, J.V. Rödig, D. Höper, U. Reichl, P.H. Seeberger, E. Rapp*, B. Lepenies*: Toward animal cell culture-based influenza vaccine design: viral hemagglutinin N-glycosylation markedly impacts immunogenicity. J. Immunol. 2013: 190(1): 220-30.

 

B. Lepenies*, J. Lee, S. Sonkaria*: Targeting C-type lectin receptors with multivalent carbohydrate ligands. Adv. Drug Deliv. Rev. 2013, 65(9): 1271-81.

 


2012

 

C.C. Williams, S.H. Thang, T. Hantke, U. Vogel, P.H. Seeberger, J. Tsanaktsidis*, B. Lepenies*: RAFT-derived polymer-drug conjugates: poly(hydroxypropyl methacryl-amide) (HPMA)-7-ethyl-10-hydroxycamptothecin conjugates. ChemMedChem 2012: 7(2): 281-91.

 

D. Kolarich, B. Lepenies, P.H. Seeberger: Glycomics, glycoproteomics and the immune system. Curr. Opin. Chem. Biol. 2012, 16(1-2): 214-20.

 

 

2011

 

M.K. Schlegel, J. Hütter, M. Eriksson, B. Lepenies, P.H. Seeberger*: Defined presentation of carbohydrates on a duplex DNA scaffold. ChemBioChem 2011: 12(18): 2791-800.

 

D. Grünstein, M. Maglinao, R. Kikkeri, M. Collot, K. Barylyuk, B. Lepenies, F. Kamena, R. Zenobi, P.H. Seeberger*: Hexameric supramolecular scaffold orients carbohydrates to sense bacteria. J. Am Chem. Soc. 2011: 133(35): 13957-66.

 

S. Khil’chenko, T. Zaporozhets, N. Shevchenko, T. Zvyagintseva, P.H. Seeberger, B. Lepenies*: Immunostimulatory activity of fucoidan from the brown alga Fucus evanescens: role of sulfates and acetates. J. Carbohydr. Chem. 2011. 30: 291-305.

 

 

2010

 

R. Gentsch, F. Pippig, K. Nilles, P. Theato, R. Kikkeri, M. Maglinao, B. Lepenies, P.H. Seeberger, H.G. Börner*: Modular approach towards bioactive fiber meshes carrying oligosaccharides. Macromolecules 2010: 43(22): 9239-47.

 

G.J. Bernardes, R. Kikkeri, M. Maglinao, P. Laurino, M. Collot, S.Y. Hong, B. Lepenies, P.H. Seeberger*: Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting. Org. Biomol. Chem. 2010: 8(21): 4987-96.

 

B. Lepenies, J. Yin, P.H. Seeberger: Applications of synthetic carbohydrates to chemical biology. Curr. Opin. Chem. Biol. 2010, 14(3): 404-11.

 

B. Lepenies, P.H. Seeberger: The promise of glycomics, glycan arrays and carbohydrate-based vaccines. Immunopharmacol. Immunotoxicol. 2010, 32(2): 196-207.

 

 

2009

 

R. Kikkeri, B. Lepenies, A. Adibekian, P. Laurino, P.H. Seeberger*: In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots. J. Am. Chem. Soc. 2009: 131(6): 2110-12.

 

P. Stallforth, B. Lepenies, A. Adibekian, P.H. Seeberger: Carbohydrates: a frontier in medicinal chemistry. J. Med. Chem. 2009, 52(18): 5561-77.

 

 

2008

 

S. Boonyarattanakalin, X. Liu, M. Michieletti, B. Lepenies, P.H Seeberger*: Chemical synthesis of all phosphatidylinositol mannoside (PIM) glycans from Mycobacterium tuberculosis. J. Am. Chem. Soc. 2008: 130(49): 16791-16799.

 

J.P. Cramer°, B. Lepenies°, F. Kamena, C. Hölscher, M.A. Freudenberg, G.D. Burchard, H. Wagner, C.J. Kirschning, X. Liu, P.H. Seeberger, T. Jacobs*: MyD88/IL-18-dependent pathways rather than TLRs control early parasitaemia in non-lethal Plasmodium yoelii infection. Microbes Infect. 2008: 10(12-13): 1259-65.

 

B. Lepenies, J.P. Cramer, G.D. Burchard, H. Wagner, C.J. Kirschning, T. Jacobs*: Induction of experimental cerebral malaria is independent of TLR2/4/9. Med. Microbiol. Immunol. 2008: 197(1): 39-44.

 

B. Lepenies, T. Jacobs: The role of negative costimulators during parasitic infections. Endocr. Metab. Immune Disord. Drug Targets. 2008, 8(4): 279-88.

 

 

2007

 

B. Lepenies, K. Pfeffer, M.A. Hurchla, T.L. Murphy, K.M. Murphy, J. Oetzel, B. Fleischer, T. Jacobs*: Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malaria. J. Immunol. 2007: 179(6): 4093-100.

 

B. Lepenies, I. Gaworski, S. Tartz, J. Langhorne, B. Fleischer, T. Jacobs*: CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections. Microbes Infect. 2007: 9(6): 687-94.