Publikationen W. Löscher

Löscher, W., & Klein, P. (2021). The pharmacology and clinical efficacy of antiseizure medications: from bromide salts to cenobamate and beyond. CNS Drugs, 35(9), 935–963. https://doi.org/10.1007/s40263-021-00827-8
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Löscher, W., Sills, G. J., & White, H. S. (2021). The ups and downs of alkyl-carbamates in epilepsy therapy: How does cenobamate differ? Epilepsia: The Journal of the International League Against Epilepsy, 62(3), 596–614. https://doi.org/10.1111/epi.16832
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Meller, S., Käufer, C., Gailus, B., Brandt, C., & Löscher, W. (2021). Scopolamine prevents aberrant mossy fiber sprouting and facilitates remission of epilepsy after brain injury. Neurobiology of Disease, 158. https://doi.org/10.1016/j.nbd.2021.105446
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Theilmann, W., Brandt, C., Bohnhorst, B., Winstroth, A.-M., Das, A. M., Gramer, M., Kipper, A., Kalesse, M., & Löscher, W. (2021). Hydrolytic biotransformation of the bumetanide ester prodrug DIMAEB to bumetanide by esterases in neonatal human and rat serum and neonatal rat brain: a new treatment strategy for neonatal seizures? Epilepsia: The Journal of the International League Against Epilepsy, 62(1), 269–278. https://doi.org/10.1111/epi.16746
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Welzel, L., Bergin, D. H., Schidlitzki, A., Twele, F., Johne, M., Klein, P., & Löscher, W. (2021). Systematic evaluation of rationally chosen multitargeted drug combinations: a combination of low doses of levetiracetam, atorvastatin and ceftriaxone exerts antiepileptogenic effects in a mouse model of acquired epilepsy. Neurobiology of Disease, 149, 105227. https://doi.org/10.1016/j.nbd.2020.105227
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Dabke, P. (2020). Mechanism of Ketogenic Diet: Impact of Beta – Hydroxybutyrate and Decanoic Acid on Sirtuins, Energy Metabolism and Cellular Lipids in a Murine Hippocampal Neuronal Cell Model. https://elib.tiho-hannover.de/receive/tiho_mods_00003661
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Debski, K. J., Ceglia, N., Ghestem, A., Ivanov, A. I., Brancati, G. E., Bröer, S., Bot, A. M., Müller, J. A., Schoch, S., Becker, A., Löscher, W., Guye, M., Sassone-Corsi, P., Lukasiuk, K., Baldi, P., & Bernard, C. (2020). The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy. Science Advances, 6(41: eaat5979). https://doi.org/10.1126/sciadv.aat5979
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Gailus, B., Johne, M., & Löscher, W. (2020). Neonatal seizures and long-term consequences in a novel rat model of birth asphyxia respond to treatment with midazolam.
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Gailus, B., & Löscher, W. (2020). Neonatal seizures and long-term consequences in a novel rat model of birth asphyxia respond to treatment with midazolam.
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Gericke, B., Brandt, C., Theilmann, W., Welzel, L., Schidlitzki, A., Twele, F., Kaczmarek, E., Anjum, M., Hillmann, P., & Löscher, W. (2020). Selective inhibition of mTORC1/2 or PI3K/mTORC1/2 signaling does not prevent or modify epilepsy in the intrahippocampal kainate mouse model. Neuropharmacology, 162: 107817. https://doi.org/10.1016/j.neuropharm.2019.107817
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