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Publications

2020

 

P. Jendrny, C. Schulz, F. Twele, S. Meller, M. von Köckritz-Blickwede, A. D. M. E. Osterhaus, J. Ebbers, V. Pilchová, I. Pink, T. Welte, M. P. Manns, A. Fathi, C. Ernst, M. M. Addo, E. Schalke & H. A. Volk. Scent dog identification of samples from COVID-19 patients – a pilot study. BMC Infectious Diseases 2020: (20)536.

 

F. Armando, M. Gambini, A. Corradi, K. Becker, K. Marek, V. M. Pfankuche, A. E. Mergani, G. Brogden, N. de Buhr, M. von Köckritz-Blickwede, H. Y. Naim, W. Baumgärtner, C. Puff. Mesenchymal to Epithelial Transition Driven by Canine Distemper Virus Infection of Canine Histiocytic Sarcoma Cells Contributes to a Reduced Cell Motility in Vitro. J. Cell. Mol. Med. 2020: doi: 10.1111/jcmm.15585.

 

Y. Lu, H. Jiang, B. Li, L. Cao, Q. Shen, W. Yi, Z. Ju, L. Chen, F. Han, D. Appelgren, M. Segelmark, N. de Buhr, M. von Köckritz-Blickwede, J. Chen. Telomere Dysfunction Promotes Small Vessel Vasculitis via the LL37-NETs-dependent Mechanism. Ann. Transl. Med. 2020: 8(6):357.


S. Schwarz, A. Lehmbecker, W. Tongtako, K. Hahn, Y. Wang, F. Felmy, I. Zdora, G. Brogden, K. Branitzki-Heinemann, M. von Köckritz-Blickwede, W. Baumgärtner, I. Gerhauser. Neurotrophic Effects of G M1 Ganglioside, NGF, and FGF2 on Canine Dorsal Root Ganglia Neurons in Vitro. Sci. Rep. 2020: 10(1):5380.


A. Neumann, G. Brogden, M. von Köckritz-Blickwede. Extracellular Traps: An Ancient Weapon of Multiple Kingdoms. Biology (Basel). 2020: 9(2):34.


S. H. Baien, J. Seele, T. Henneck, C. Freibrodt, G. Szura, H. Moubasher, R. Nau, G. Brogden, M. Mörgelin, M. Singh, M. Kietzmann, M. von Köckritz-Blickwede, N. de Buhr. Antimicrobial and Immunomodulatory Effect of Gum Arabic on Human and Bovine Granulocytes Against Staphylococcus aureus and Escherichia coli. Front Immunol. 2020: 10:3119.


F. Armando, M. Gambini, A. Corradi, C. Giudice, V. M. Pfankuche, G. Brogden, F. Attig, M. von Köckritz-Blickwede, W. Baumgärtner, C. Puff. Oxidative Stress in Canine Histiocytic Sarcoma Cells Induced by an Infection With Canine Distemper Virus Led to a Dysregulation of HIF-1α Downstream Pathway Resulting in a Reduced Expression of VEGF-B in Vitro. Virsues. 2020: 12(2).


M. Meurer, N. de Buhr, L. M. Unger, M. C. Bonilla, J. Seele, R. Nau, C. G. Baums, T. Gutsmann, S. Schwarz, M. von Köckritz-Blickwede. Comparing Cathelicidin Susceptibility of the Meningitis Pathogens Streptococcus suis and Escherichia coli in Culture Medium in Contrast to Porcine or Human Cerebrospinal Fluid. Front Microbiol. 2020: 10:2911.


F. S. Hohnstein, M. Meurer, N. de Buhr, M. von Köckritz-Blickwede, C. G Baums, G. Alber, N. Schütze. Analysis of Porcine Pro- And Anti-Inflammatory Cytokine Induction by S. suis In Vivo and In Vitro. Pathogens. 2020: 9(1):40.


N. de Buhr & M. von Köckritz-Blickwede. Detection, Visualization, and Quantification of Neutrophil Extracellular Traps (NETs) and NET Markers. Methods Mol Biol. 2020:2087:425-442.


K. Branitzki-Heinemann, G. Brogden, M. von Köckritz-Blickwede. Influence of Oxygen on Function and Cholesterol Composition of Murine Bone Marrow-Derived Neutrophils. Methods. Mol. Biol. 2020: 2087:223-233.


L. E. Cox, K. Walstein, L. Völlger, F. Reuner, A. Bick, A. Dötsch, A. Engler, J. Peters, M. von Köckritz-Blickwede, S. T. Schäfer. Neutrophil Extracellular Trap Formation and Nuclease Activity in Septic Patients. BMC Anesthesiol. 2020: 20(1):15.


V. Rungelrath, S. Öhlmann, G. Alber, W. Schrödl, M. von Köckritz-Blickwede, N. de Buhr, A. Martens, C. G. Baums, N. Schütze. Survival of Streptococcus Suis in Porcine Blood Is Limited by the Antibody- And Complement-Dependent Oxidative Burst Response of Granulocytes. Infect Immun. 2020: 88(3):e00598-19.


C. Schulz, G. Gabriel, M. von Köckritz-Blickwede. Detrimental Role of Neutrophil Extracellular Traps During Dengue Virus Infection. Trends Immunol. 2020: 41(1):3-6.

 

 

2019


R. Bergmann, M.-C. Jentsch, A. Uhlig, U. Müller, M. van der Linden, M. Rasmussen, A. Waller, M. von Köckritz-Blickwede, C. G. Baums. Prominent Binding of Human and Equine Fibrinogen to Streptococcus Equi Subsp. zooepidemicus Is Mediated by Specific SzM Types and Is a Distinct Phenotype of Zoonotic Isolates. Infect. Immun. 2019: 88(1):e00559-19.


L. Fingerhut, B. Ohnesorge, M. von Borstel, A. Schumski, K. Strutzberg-Minder, M. Mörgelin, C. A. Deeg, H. P. Haagsman, A. Beineke, M. von Köckritz-Blickwede, N. de Buhr. Neutrophil Extracellular Traps in the Pathogenesis of Equine Recurrent Uveitis (ERU). Cells. 2019: 8(12):1528.


M. S. Bickes, S. Pirr, A. S. Heinemann, B. Fehlhaber, S. Halle, L. Völlger, M. Willers, M. Richter, C. Böhne, M. Albrecht, M. Langer, S. Pfeifer, D. Jonigk, G. Vieten, B. Ure, C. von Kaisenberg, R. Förster, M. von Köckritz-Blickwede, G. Hansen, D. Viemann. Constitutive TNF-α Signaling in Neonates Is Essential for the Development of Tissue-Resident Leukocyte Profiles at Barrier Sites. FASEB J. 2019: 33(10):10633-10647.


N. de Buhr, M. C. Bonilla, J. Pfeiffer, S. Akhdar, C. Schwennen, B. C. Kahl, K.-H. Waldmann, P. Valentin-Weigand, I. Hennig-Pauka, M. von Köckritz-Blickwede. Degraded Neutrophil Extracellular Traps Promote the Growth of Actinobacillus Pleuropneumoniae. Cell. Death. Dis. 2019: 10(9):657.


S. Herzog, F. Dach, N. de Buhr, S. Niemann, J. Schlagowski, D. Chaves-Moreno, C. Neumann, J. Goretzko, V. Schwierzeck, A. Mellmann, A. Dübbers, P. Küster, H. Schültingkemper, U. Rescher, D. H. Pieper, M. von Köckritz-Blickwede, B. C. Kahl. High Nuclease Activity of Long Persisting Staphylococcus aureus Isolates Within the Airways of Cystic Fibrosis Patients Protects Against NET-Mediated Killing. Front Immunol. 2019:10:2552.


B. Fehlhaber, A. S. Heinemann, K. Rübensam, M. Willers, L. Völlger, S. Pfeifer, M. von Köckritz-Blickwede, D. Viemann. A Sensitive Scoring System for the Longitudinal Clinical Evaluation and Prediction of Lethal Disease Outcomes in Newborn Mice. Sci. Rep. 2019: 9(1):5919.


S. Boeltz, P. Amini, H.-J. Anders, F. Andrade, R. Bilyy, S. Chatfield, I. Cichon, D. M Clancy, J. Desai, T. Dumych, N. Dwivedi, R. A. Gordon, J. Hahn, A. Hidalgo, M. H. Hoffmann  14 , M. J. Kaplan, J. S. Knight, E. Kolaczkowska, P. Kubes, M. Leppkes, A. A. Manfredi, S. J. Martin, C. Maueröder, N. Maugeri, I. Mitroulis, L. E Munoz, D. Nakazawa, I. Neeli, V. Nizet, E. Pieterse, M. Z. Radic, C. Reinwald, K. Ritis, P. Rovere-Querini, M. Santocki, C. Schauer, G. Schett, M. J. Shlomchik, H.-U. Simon, P. Skendros, D. Stojkov, P. Vandenabeele, T. V. Berghe, J. van der Vlag, L. Vitkov, M. von Köckritz-Blickwede, S. Yousefi, A. Zarbock, M. Herrmann. To NET or Not to NET:current Opinions and State of the Science Regarding the Formation of Neutrophil Extracellular Traps. Cell. Death. Differ. 2019: 26(3):395-408.

 

 

2018


A. Noack, B. Gericke, M. von Köckritz-Blickwede, A. Menze, S. Noack, I. Gerhauser, F. Osten, H. Y. Naim, W. Löscher. Mechanism of Drug Extrusion by Brain Endothelial Cells via Lysosomal Drug Trapping and Disposal by Neutrophils. Proc. Natl. Acad. Sci. U S A. 2018: 115(41):E9590-E9599.


K. A. Lis, C. Kehrenberg, A. Boulaaba, M. von Köckritz-Blickwede, S. Binder, Y. Li, J. L. Zimmermann, Y. Pfeifer, B. Ahlfeld. Inactivation of Multidrug-Resistant Pathogens and Yersinia Enterocolitica With Cold Atmospheric-Pressure Plasma on Stainless-Steel Surfaces. Int. J. Antimicrob. Agents. 2018: 52(6):811-818.


S. H. Baien, M. N. Langer, M. Heppelmann, M. von Köckritz-Blickwede, N. de Buhr. Comparison Between K 3 EDTA and Lithium Heparin as Anticoagulant to Isolate Bovine Granulocytes From Blood. Front. Immunol. 2018: 9:1570.


C. Kleinsorgen, M. von Köckritz-Blickwede, H. Y. Naim, K. Branitzki-Heinemann, M. Kankofer, M. Mándoki, M. Adler, A. Tipold, J. P. Ehlers. Impact of Virtual Patients as Optional Learning Material in Veterinary Biochemistry Education. J. Vet. Med. Educ. 2018: 45(2):177-187.


N. de Buhr, M. C. Bonilla, M. Jimenez-Soto, M. von Köckritz-Blickwede, G. Dolz. Extracellular Trap Formation in Response to Trypanosoma cruzi Infection in Granulocytes Isolated From Dogs and Common Opossums, Natural Reservoir Hosts. Front. Microbiol. 2018:9:966.


M. Henström, L. Diekmann, F. Bonfiglio, F. Hadizadeh, E.-M. Kuech, M. von Köckritz-Blickwede, L. B. Thingholm, T. Zheng, G. Assadi, C. Dierks, M. Heine, U. Philipp, O. Distl, M. E. Money, M. Belheouane, F.-A. Heinsen, J. Rafter, G. Nardone, R. Cuomo, P. Usai-Satta, F. Galeazzi, M. Neri, S. Walter, M. Simrén, P. Karling, B. Ohlsson, P. T. Schmidt, G. Lindberg, A. Dlugosz, L. Agreus, A. Andreasson, E. Mayer, J. F. Baines, L. Engstrand, P. Portincasa, M. Bellini, V. Stanghellini, G. Barbara, L. Chang, M. Camilleri, A. Franke, H. Y. Naim, M. D'Amato. Functional Variants in the Sucrase-Isomaltase Gene Associate With Increased Risk of Irritable Bowel Syndrome. Gut. 2018: 67(2):263-270.


S. Grasso, A. Neumann, I. M. Lang, M. Etscheid, M. von Köckritz-Blickwede, S. M. Kanse. Interaction of Factor VII Activating Protease (FSAP) With Neutrophil Extracellular Traps (NETs). Thromb. Res. 2018: 161:36-42.

 

 

2017


M. N. Langer, S. Blodkamp, M. Bayerbach, A. T. Feßler, N. de Buhr, T. Gutsmann, L. Kreienbrock, S. Schwarz, M. von Köckritz-Blickwede. Testing Cathelicidin Susceptibility of Bacterial Mastitis Isolates: Technical Challenges and Data Output for Clinical Isolates. Vet. Microbiol. 2017: 210:107-115.


T. Ulas, S. Pirr, B. Fehlhaber, M. S. Bickes, T. G. Loof, T. Vogl, L. Mellinger, A. S. Heinemann, J. Burgmann, J. Schöning, S. Schreek, S. Pfeifer, F. Reuner, L. Völlger, M. Stanulla, M. von Köckritz-Blickwede, S. Glander, K. Barczyk-Kahlert, C. S. von Kaisenberg, J. Friesenhagen, L. Fischer-Riepe, S. Zenker, J. L. Schultze, J. Roth, D. Viemann. Corrigendum: S100-alarmin-induced Innate Immune Programming Protects Newborn Infants From Sepsis. Nat. Immunol. 2017: 18(10):1173.


R. Yaseen, K. Branitzki-Heinemann, H. Moubasher, W. N. Setzer, H. Y. Naim, M. von Köckritz-Blickwede. In Vitro Testing of Crude Natural Plant Extracts From Costa Rica for Their Ability to Boost Innate Immune Cells Against Staphylococcus Aureus. Biomedicines. 2017: 5(3):40.


H. Möllerherm, K. Meier, K. Schmies, H. Fuhrmann, H. Y. Naim, M. von Köckritz-Blickwede, K. Branitzki-Heinemann. Differentiation and Functionality of Bone Marrow-Derived Mast Cells Depend on Varying Physiologic Oxygen Conditions. Front. Immunol. 2017: 8:1665.


C. Kleinsorgen, M. Kankofer, Z. Gradzki, M. Mandoki, T. Bartha, M. von Köckritz-Blickwede, H. Y. Naim, M. Beyerbach, A. Tipold, J. P. Ehlers. Utilization and Acceptance of Virtual Patients in Veterinary Basic Sciences - The vetVIP-project. GMS J. Med. Educ. 2017: 34(2):Doc19.


H. Möllerherm, K. Branitzki-Heinemann, G. Brogden, A. A. Elamin, W. Oehlmann, H. Fuhrmann, M. Singh, H. Y. Naim, M. von Köckritz-Blickwede. Hypoxia Modulates the Response of Mast Cells to Staphylococcus aureus Infection. Front Immunol. 2017: 8:541.


G. Brogden, A. Neumann, D. M. Husein, F. Reuner, H. Y. Naim, M. von Köckritz-Blickwede. Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps. J. Vis. Exp. 2017: (121):54667.


G. Brogden, H. Shammas, K. Maalouf, S. L. Naim, G. Wetzel, M. Amiri, M. von Köckritz-Blickwede, A. M. Das, H. Y. Naim. Case Study on the Pathophysiology of Fabry Disease: Abnormalities of Cellular Membranes Can Be Reversed by Substrate Reduction in vitro. Biosci. Rep. 2017: 37(2):BSR20160402.


S. Blodkamp, K. Kadlec, T. Gutsmann, C. Quiblier, H. Y. Naim, S. Schwarz, M. von Köckritz-Blickwede. Effects of SecDF on the Antimicrobial Functions of Cathelicidins Against Staphylococcus Aureus. Vet. Microbiol. 2017: 200:52-58.


N. de Buhr, F. Reuner, A. Neumann, C. Stump-Guthier, T. Tenenbaum, H. Schroten, H. Ishikawa, K. Müller, A. Beineke, I. Hennig-Pauka, T. Gutsmann, P. Valentin-Weigand, C. G. Baums, M. von Köckritz-Blickwede. Neutrophil Extracellular Trap Formation in the Streptococcus Suis-Infected Cerebrospinal Fluid Compartment. Cell. Microbiol. 2017: 19(2).


R. Yaseen, S. Blodkamp, P. Lüthje, F. Reuner, L. Völlger, H. Y. Naim, M. von Köckritz-Blickwede. Antimicrobial Activity of HL-60 Cells Compared to Primary Blood-Derived Neutrophils Against Staphylococcus Aureus. J. Negat. Results. Biomed. 2017: 16(1):2.
A.S. Heinemann, S. Pirr, B. Fehlhaber, L. Mellinger, J. Burgmann, M. Busse, M. Ginzel, J. Friesenhagen, M. von Köckritz-Blickwede, T. Ulas, C.S. von Kaisenberg, J. Roth, T. Vogl, D. Viemann. In neonates S100A8/S100A9 alarmins prevent the expansion of a specific inflammatory monocyte population promoting septic shock. FASEB J. 2017:31(3):1153-1164.


 
2016


K. Branitzki-Heinemann, H. Möllerherm, L. Völlger, D.M. Husein, N. de Buhr, S. Blodkamp, F. Reuner, G. Brogden, H.Y. Naim, M. von Köckritz-Blickwede. Formation of Neutrophil Extracellular Traps under Low Oxygen Level. Front Immunol. 2016:7:518.

 
M. Henström, L. Diekmann, F. Bonfiglio, F. Hadizadeh, E.M. Kuech, M. von Köckritz-Blickwede, L.B. Thingholm, T. Zheng, G. Assadi, C. Dierks, M. Heine, U. Philipp, O. Distl, M.E. Money, M. Belheouane, F.A. Heinsen, J. Rafter, G. Nardone, R. Cuomo, P. Usai-Satta, F. Galeazzi, M. Neri, S. Walter, M. Simrén, P. Karling, B. Ohlsson, P.T. Schmidt, G. Lindberg, A. Dlugosz, L. Agreus, A. Andreasson, E. Mayer, J.F. Baines, L. Engstrand, P. Portincasa, M. Bellini, V. Stanghellini, G. Barbara, L. Chang, M. Camilleri, A. Franke, H.Y. Naim, M. D'Amato. Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome. Gut. 2018:67(2):263-270.


N. de Buhr, F. Reuner, A. Neumann, C. Stump-Guthier, T. Tenenbaum, H. Schroten, H. Ishikawa, K. Müller, A. Beineke, I. Hennig-Pauka, T. Gutsmann, P. Valentin-Weigand, C.G. Baums, M. von Köckritz-Blickwede. Neutrophil extracellular trap formation in the Streptococcus suis-infected cerebrospinal fluid compartment. Cell Microbiol. 2017:19(2).


S. Blodkamp, K. Kadlec, T. Gutsmann, H. Y. Naim, M. von Köckritz-Blickwede, S. Schwarz. In Vitro Activity of Human and Animal Cathelicidins Against Livestock-Associated Methicillin-Resistant Staphylococcus Aureus. Vet. Microbiol. 2016: 194:107-111.


H. Möllerherm, M. von Köckritz-Blickwede, K. Branitzki-Heinemann. Antimicrobial Activity of Mast Cells: Role and Relevance of Extracellular DNA Traps. Front Immunol. 2016:7:265.


N. Jerjomiceva, H. Seri, R. Yaseen, N. de Buhr, W. N. Setzer, H. Y. Naim, M. von Köckritz-Blickwede. Guarea Kunthiana Bark Extract Enhances the Antimicrobial Activities of Human and Bovine Neutrophils. Nat. Prod. Commun. 2016: 11(6):767-70.


H. Möllerherm, M. von Köckritz-Blickwede, K. Branitzki-Heinemann. Antimicrobial Activity of Mast Cells: Role and Relevance of Extracellular DNA Traps. Front. Immunol. 2016: 7:265.


N. Jerjomiceva, H. Seri, R. Yaseen, N. de Buhr, W.N. Setzer, H.Y. Naim, M. von Köckritz-Blickwede. Guarea kunthiana Bark Extract Enhances the Antimicrobial Activities of Human and Bovine Neutrophils. Nat. Prod. Commun. 2016:11(6):767-70.


L. Völlger, K. Akong-Moore, L. Cox, O. Goldmann, Y. Wang, S.T. Schäfer, H.Y. Naim, V. Nizet, M. von Köckritz-Blickwede. Iron-chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils. Biosci. Rep. 2016:36(3). 


D.A. Stapels, A. Kuipers, M. von Köckritz-Blickwede, M. Ruyken, A.T. Tromp, M.J. Horsburgh, C.J. de Haas, J.A. van Strijp, K.P. van Kessel, S.H. Rooijakkers. Staphylococcus aureus protects its immune-evasion proteins against degradation by neutrophil serine proteases. Cell Microbiol. 2016:18(4):536-45.


N. de Buhr, M. von Köckritz-Blickwede. How Neutrophil Extracellular Traps Become Visible. J. Immunol. Res. 2016: 4604713.


L. Andzinski, N. Kasnitz, S. Stahnke, C.-F. Wu, M. Gereke, M. von Köckritz-Blickwede, B. Schilling, S. Brandau, S. Weiss, J. Jablonska. Type I IFNs Induce Anti-Tumor Polarization of Tumor Associated Neutrophils in Mice and Human. Int. J. Cancer. 2016: 138(8):1982-93.


S. Blodkamp, K. Kadlec, T. Gutsmann, C. Quiblier, H.Y. Naim, S. Schwarz, M. von Köckritz-Blickwede. Effects of SecDF on the antimicrobial functions of cathelicidins against Staphylococcus aureus. Vet Microbiol. 2017:200:52-58.


M. von Köckritz-Blickwede, S. Blodkamp, V. Nizet. Interaction of Bacterial Exotoxins with Neutrophil Extracellular Traps: Impact for the Infected Host. Front. Microbiol. 2016:7:402. 
N.E. Zeitouni, S. Chotikatum, M. von Köckritz-Blickwede, H.Y. Naim. The impact of hypoxia on intestinal epithelial cell functions: consequences for invasion by bacterial pathogens. Mol. Cell. Pediatr. 2016:3(1):14.


N.E. Zeitouni, P. Dersch, H.Y. Naim, M. von Köckritz-Blickwede. Hypoxia Decreases Invasin-Mediated Yersinia enterocolitica Internalization into Caco-2 Cells. PLoS One. 2016:11(1):e0146103.


 
2015


N.E. Zeitouni, J. Fandrey, H.Y. Naim, M. von Köckritz-Blickwede. Measuring oxygen levels in Caco-2 cultures. Hypoxia (Auckl). 2015:3:53-66.


H. Möllerherm, A. Neumann, K. Schilcher, S. Blodkamp, N.E. Zeitouni, P. Dersch, P. Lüthje, H.Y. Naim, A.S. Zinkernagel, M. von Köckritz-Blickwede. Yersinia enterocolitica-mediated degradation of neutrophil extracellular traps (NETs). FEMS Microbiol. Lett. 2015:362(23):fnv192.


M. Amiri, L. Diekmann, M. von Köckritz-Blickwede, H.Y. Naim. The Diverse Forms of Lactose Intolerance and the Putative Linkage to Several Cancers. Nutrients. 2015: 7(9):7209-30.


C.G. Baums, M. von Köckritz-Blickwede. Novel role of DNA in neutrophil extracellular traps. Trends Microbiol. 2015: 23(6):330-1.


 L.P. Coelho, C. Pato, A. Friães, A. Neumann, M. von Köckritz-Blickwede, M. Ramirez, J.A. Carriço. Automatic determination of NET (neutrophil extracellular traps) coverage in fluorescent microscopy images. Bioinformatics. 2015: 31(14):2364-70.


N. de Buhr, M. Stehr, A. Neumann, H.Y. Naim, P. Valentin-Weigand, M. von Köckritz-Blickwede, C.G. Baums. Identification of a novel DNase of Streptococcus suis (EndAsuis) important for neutrophil extracellular trap degradation during exponential growth. Microbiology. 2015: 161(Pt 4):838-50.
 


2014


J. Austermann, J. Friesenhagen, S.K. Fassl, T. Ortkras, J. Burgmann, K. Barczyk-Kahlert, E. Faist, S. Zedler, S. Pirr, C. Rohde, C. Muller-Tidow, M. von Köckritz-Blickwede, C.S. von Kaisenberg, S.B. Flohe, T. Ulas, J.L. Schultze, J. Roth, T. Vogl, V. Viemann. Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions. Cell. Rep. 2014: 9(6):2112-23.


D. Seinige, M. von Köckritz-Blickwede, C. Krischek, G. Klein, C. Kehrenberg. Influencing factors and applicability of the viability EMA-qPCR for a detection and quantification of campylobacter cells from water samples. PLoS One. 2014: 9(11):e113812.


A. Neumann, E.T. Berends, A. Nerlich, E.M. Molhoek, R.L. Gallo, T. Meerloo, V. Nizet, H.Y. Naim, M. von Köckritz-Blickwede. The antimicrobial peptide LL-37 facilitates the formation of neutrophil extracellular traps. Biochem J. 2014: 464(1):3-11.


A. Neumann, G. Brogden, N. Jerjomiceva, S. Brodesser, H.Y. Naim, M. von Köckritz-Blickwede. Lipid alterations in human blood-derived neutrophils lead to formation of neutrophil extracellular traps. Eur. J. Cell. Biol. 2014: 93(8-9):347-54.


D.A. Stapels, K.X. Ramyar, M. Bischoff, M. von Köckritz-Blickwede, F.J. Milder, M. Ruyken, J. Eisenbeis, W.J. McWhorter, M. Herrmann, K.P. van Kessel, B.V. Geisbrecht, S.H. Rooijakkers. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc. Natl. Acad. Sci. U S A. 2014: 111(36):13187-92.


 A. Neumann, L. Völlger, E.T.M. Berends, E.M. Molhoek, D.A.C. Stapels, M. Midon, A. Friães, A. Pingoud, S.H.M. Rooijakkers, R.L. Gallo, M. Mörgelin, V. Nizet, H.Y. Naim, M. von Köckritz-Blickwede. Novel role of the antimicrobial peptide LL-37 in the protection of neutrophil extracellular traps against degradation by bacterial nucleases. J. Innate Immun. 2014: 6(6):860-8.


N. Jerjomiceva, H. Seri, L. Völlger, Y. Wang, N. Zeitouni, H.Y. Naim, M. von Köckritz-Blickwede. Enrofloxacin enhances the formation of neutrophil extracellular traps in bovine granulocytes. J. Innate Immun. 2014: 6(5):706-12.


G. Brogden, T. Krimmling, M. Adamek, H.Y. Naim, D. Steinhagen, M. von Köckritz-Blickwede. The effect of β-glucan on formation and functionality of neutrophil extracellular traps in carp (Cyprinus carpio L.). Dev. Comp. Immunol. 2014: 44(2):280-5.


N. de Buhr, A. Neumann, N. Jerjomiceva, M. von Köckritz-Blickwede, C.G. Baums. Streptococcus suis DNase SsnA contributes to degradation of neutrophil extracellular traps (NETs) and evasion of NETmediated antimicrobial activity. Microbiology. 2014: 160(Pt 2):385-95.


K.R. Short, M. von Köckritz-Blickwede, J.D. Langereis, K.Y. Chew, E.R. Job, C.W. Armitage, B. Hatcher, K. Fujihashi, P.C. Reading, P.W. Hermans, O.L. Wijburg, D.A. Diavatopoulos. Antibodies mediate the formation of neutrophil extracellular traps (NETs) in the middle ear and facilitate secondary pneumococcal otitis media. Infect. Immun. 2014: 81(1):364-70.

 


2013


N.M. van Sorge, F.C. Beasley, I. Gusarov, D.J. Gonzalez, M. von Köckritz-Blickwede, S. Anik, A.W. Borkowski, P.C. Dorrestein, E. Nudler, V. Nizet. Methicillin-resistant Staphylococcus aureusBacterial Nitricoxide Synthase Affects Antibiotic Sensitivity and Skin Abscess Development. J. Biol. Chem. 2013: 288(9):6417-26.
 


2012


G. Brogden, M. von Köckritz-Blickwede, M. Adamek, F. Reuner, V. Jung-Schroers, H.Y. Naim, D. Steinhagen. β-glucan protects neutrophil extracellular traps against degradation by Aeromonas hydrophila in carp (Cyprinus carpio). Fish Shellfish Immunol. 2012: 33(4):1060-4.


K. Akong-Moore, O.A. Chow, M. von Köckritz-Blickwede, V. Nizet. Influences of chloride and hypochlorite on neutrophil extracellular trap formation. PLoS One. 2012: 7(8):e42984.


K. Branitzki-Heinemann, C.Y. Okumura, L. Völlger, Y. Kawakami, T. Kawakami, H.Y. Naim, V. Nizet, M. von Köckritz-Blickwede. A novel role for the transcription factor HIF-1α in the formation of mast cell extracellular traps. Biochem. J. 2012:  446(1):159-63.

C.Y. Okumura, A. Hollands, D.N. Tran, J. Olson, S. Dahesh, M. von Köckritz-Blickwede, W. Thienphrapa, C. Corle, S.N. Jeung, A. Kotsakis, R.A. Shalwitz, R.S. Johnson, V. Nizet. A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection. J. Mol. Med. (Berl). 2012: 90(9):1079-89.


I. Jongerius, M. von Köckritz-Blickwede, M.J. Horsburgh, M. Ruyken, V. Nizet, S.H. Rooijakkers. Staphylococcus aureus virulence is enhanced by secreted factors that block innate immune defenses. J. Innate Immun. 2012: 4(3):301-11.


A.S. Zinkernagel, P. Hruz, S. Uchiyama, M. von Köckritz-Blickwede, R.A. Schuepbach, T. Hayashi, D.A. Carson, V. Nizet. Importance of Toll-like receptor 9 in host defense against M1T1 Group A Streptococcus infections. J. Innate Immun. 2012:  4:213-8.

 

 

2011


T. Kisseleva, M. von Köckritz-Blickwede, D. Reichart, S.M. McGillvray, G. Wingender, M. Kronenberg, C.K. Glass, V. Nizet, D.A. Brenner. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J. Mol. Med. (Berl.) 2011: 89:997-1013.
 


2010


O.A. Chow, M. von Köckritz-Blickwede, A.T. Bright, M.E. Hensler, A.S. Zinkernagel, A.L. Cogen, R.L. Gallo, Y. Wang, C.K. Glass, V. Nizet. Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010: 8:445-54.


E.T.M. Berends, A.R. Horswill, N.M. Haste, V. Nizet, M. von Köckritz-Blickwede. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J. Innate Immun. 2010: 2:576-86.


J.N. Cole, M.A. Pence, M. von Köckritz-Blickwede, A. Hollands, R.L. Gallo, M.J. Walker, V. Nizet. M protein and hyaluronic acid capsule are essential for the genetic switch underlying hypervirulence in M1T1 group A streptococcus. mBio. 2010: 1(4):e00191-10.


M. von Köckritz-Blickwede, S. Konrad, S. Foster, J.E. Gessner, E. Medina. Protective role of complement C5a in an experimental model of Staphylococcus aureus bacteremia. J. Innate Immun. 2010: 2:87–92.


L.E. Crotty Alexander, H.C. Maisey, A.M. Timmer, S.H.M. Rooijakkers, R.L. Gallo, M. von Köckritz-Blickwede, V. Nizet. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J. Mol. Med. 2010: 88:371-81.


 
2009


M. von Köckritz-Blickwede, O.A. Chow, V. Nizet. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood. 2009: 114:5245-6.


M. von Köckritz-Blickwede, V. Nizet. Innate immunity turned inside-out: Antimicrobial defense by phagocyte extracellular traps. J. Mol. Med. 2009: 87:775-83.


S. Oehmcke, O. Shannon, M. von Köckritz-Blickwede, M. Mörgelin, A. Linder, A.I. Olin, L. Björck, H. Herwald. Treatment of invasive streptococcal infection with a peptide derived from human highmolecular weight kininogen. Blood. 2009: 114:444-51.


X. Lauth, M. von Köckritz-Blickwede, C.W. McNamara, S. Myskowski, A.S. Zinkernagel, B. Beall, P. Ghosh, R.L. Gallo, V. Nizet. M1 protein allows group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J. Innate Immun. 2009: 1:202-14.

 

 

2008


M. von Köckritz-Blickwede, M. Rohde, S. Oehmcke, L.S. Miller, A.L. Cheung, H. Herwald, S. Foster, E. Medina. Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model. Am. J. Pathol. 2008: 173:1657-68.


M. von Köckritz-Blickwede, O. Goldmann, K. Heinemann, P. Thulin, A. Norrby-Teglund, M. Rohde, E. Medina. Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation. Blood. 2008: 111:3070-80.

 

 

2007


O. Goldmann, M. von Köckritz-Blickwede, C. Höltje, G.S. Chatwal, R. Geffers, E. Medina. Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes reveals an unusual activation program. Infect. Immun. 2007: 75:4148-57.


P. Lüthje, M. von Köckritz-Blickwede and S. Schwarz. Identification and characterization of nine novel types of small staphylococcal plasmids carrying the lincosamide nucleotidyltransferase gene lnu(A). J. Antimicrob. Chemother. 2007: 59:600-6.
 


2006


T. Hansen, M. Blickwede, J. Borlak. Primary rat alveolar epithelial cells for use in biotransformation and toxicity studies. Toxicol. In Vitro. 2006: 20:757-66.
 


2005


M. Blickwede, J. Borlak. Isolation and characterization of metabolically competent pulmonary epithelial cells from pig lung tissue. Xenobiotica. 2005: 35:927-41.


J. Borlak, M. Blickwede, T. Hansen, W. Koch, M. Walles, K. Levsen. Metabolism of verapamil in culturesof rat alveolar epithelial cells and pharmacokinetics after administration by intravenous and inhalation routes. Drug. Metab. Dispos. 2005: 33:1108-14.


M. Blickwede, C. Wolz, P. Valentin-Weigand, S. Schwarz. Influence of clindamycin on mRNA stability of coa and fnbB transcripts and adherence properties of Staphylococcus aureus Newman. FEMS Microbiol. Lett. 2005: 252:73-8.


M. Blickwede, R. Goethe, C. Wolz, P. Valentin-Weigand, S. Schwarz. Molecular basis of florfenicolinduced increase in adherence of Staphylococcus aureus strain Newman. J. Antimicrob. Chemother. 2005: 56:315-23.

 

 

2004


M. Blickwede, P. Valentin-Weigand, M. Rohde, S. Schwarz. Effects of subinhibitory concentrations of florfenicol on morphology, growth, and viability of Staphyloccus aureus. J. Vet. Med. 2004: 51:293-6.


M. Blickwede, P. Valentin-Weigand, S. Schwarz. Subinhibitory concentrations of florfenicol enhance the adherence of florfenicol-susceptible and florfenicol-resistant Staphylococcus aureus. J. Antimicrob. Chemother. 2004: 54:286-8.


M. Blickwede, S. Schwarz. Molecular analysis of florfenicol-resistant Escherichia coli isolates from pigs. J. Antimicrob. Chemother. 2004: 53:58-64.
 


2003


S. Schwarz, M. Blickwede, C. Kehrenberg, G. Michael Brenner. Phänotypische und genotypische Verfahren zur Typisierung veterinärmedizinisch relevanter bakterieller Erreger im Rahmen infektionsepidemiologischer Fragestellungen, dargestellt am Beispiel von Bakterien der Genera Staphylococcus, Salmonella und Pasteurella. Berl Münch Tierärztl Wschr. 2003: 116:401-16.


 
2002


M. Blickwede, H. Dolz, M.V. Herrero, S.M. Tomlinson, M. Salman. Neutralizing antibodies against vesicular stomatitis viruses (serotypes New Jersey and Indiana) in horses in Costa Rica. J. Vet. Diagn. Invest. 2002: 14:438-41.

 

Kontakt
Dr. Tina Basler
Tel.:+49 511 953-6141
Fax.:+49 511 953-8675
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