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Project Leader

Prof. Dr. Gisa Gerold

Gisa Gerold studied at the Eberhard Karls University Tübingen, Germany, where she graduated with a diploma in biochemistry (minors: physical chemistry and microbiology). In 2008, she received a PhD in biology and biochemistry from the Humboldt University Berlin, Germany. She performed her PhD research at the Max Planck Institute for Infection Biology under the supervision of Professor Arturo Zychlinsky on the innate immunity to bacterial infections. The work was awarded the Otto Hahn Medal for Outstanding Scientific Achievements by the Max Planck Society.During her three-year postdoctoral stay at the "Center of Hepatitis C" of the Rockefeller University, New York, USA headed by Professor Charles M. Rice, she worked on various aspects of hepatitis C virus (HCV) infection, including the species tropism and HCV-related viruses in animals. From 2012 until 2017 she continued her work at the Twincore, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research. There, she investigated mechanisms of HCV entry into liver cells using a combination of mass spectrometry based protein analytics and virological methods. For her postdoc positions she received independent stipends from the National Academy of Sciences Leopoldina, the  Human Frontiers Science Program (HFSP) and the German Research Foundation (DFG). Her postdoc work was awarded the Robert Koch postdoctoral prize in Virology in 2017.
From 2017 until 2020 Gisa Gerold headed the research group „Virus Interaction Proteomics“ at Twincore and since 2018 she holds a Guest Professorship at Umeå University in Schweden. Her work at the Wallenberg Center for Molecular Medicine (WCMM) is funded by the Knut and Alice Wallenberg Foundation and the Kempe Foundation. Gisa Gerold’s German-Swedish team is driven by the interest to understand the entry of diverse human pathogenic viruses including HCV, noroviruses and Chikungunyavirus into their host cells and by the interest to shed light on the innate defense of host cells against viruses. Using state of the art technologies including label free proteomics her team wants to delineate fundamental principles of virus entry and virus recognition by cells.
Since 2019 Gisa Gerold is a board member of the Center for Infection Biology (ZIB) of Hannover Medical School and since 2020 associated member of the Excellence Cluster RESIST. From 2017 until 2018 Gisa Gerold organized –together with her colleague Dr. Pierre-Yves Lozach (Universität Lyon) the annual workshop “Cell Biology of Viral Infections” oft he German Society for Virology (GfV), in which she was elected advisory board member in 2020.
Gisa Gerold became Professor for Biochemistry – Focus Molecular and Clinical Infectiology at the Veterinary University Hannover in 2020. Here her team is a member of the Institute of Biochemistry and is located at the „Research Center for Emerging Infections and Zoonoses“ (RIZ), where they investigate pathogenic viruses, which are transmitted from animals to humans. The focus of her work is on mosquito-transmitted viruses of the alphavirus genus, but also other zoonotic pathogens such as arenaviruses and gastrointestinal pathogens such as noroviruses are under investigation.
Methodologically the team of Gisa Gerold uses modern proteomics approaches to identify host factors of viruses with the potential to cause future epidemics. Thereby the group aims to understand, which hosts can be infected and how the viruses cause disease in the specific tissues of man and animals.The work in Germany is funded by the German Research Foundation (DFG), the Lower Saxony Ministry of Science and Culture (MWK), the Federal Ministry of Education and Research (BMBF) and the German Academic Exchange Service (DAAD).
The Swedish research is supported by the Knut and Alice Wallenberg Foundation, the Kempe Foundation and the Erling-Persson Foundation.

Kontakt
Dr. Tina Basler
Tel.:+49 511 953-6141
Fax.:+49 511 953-8675
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