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Publications

2018

A.W. Rimoin, K. Lu, M.S. Bramble, I. Steffen, R.H. Doshi, N.A. Hoff, P. Mukadi,

B.P. Nicholson, V.H. Alfonso, G. Olinger, C. Sinai, L.K. Yamamoto, C.M. Ramirez,

E. Okitolonda Wemakoy, B. Kebela Illunga, J. Pettitt, J. Logue, R.S. Bennett,

P. Jahrling, D.L. Heymann, P. Piot, J.J. Muyembe-Tamfum, L.E. Hensley, G. Simmons.

Ebola Virus Neutralizing Antibodies Detectable in Survivors of the Yambuku,

Zaire Outbreak 40 Years after Infection. J Infect Dis. 2018 Jan 4;217(2):223-231.

 

2016

I. Steffen and G. Simmons. (2016) Pseudotyping viral vectors with emerging virus

envelope proteins. Current Gene Therapy, 16(1):47-55.

 

2015

I. Steffen and G. Simmons. (2015) Coronaviruses. eLS Citable reviews in the life

sciences, Wiley, DOI: 10.1002/9780470015902.a0023611.

 

I. Steffen and G. Simmons. (2015) Emerging Rhabdoviruses. In Biology and

Pathogenesis of Rhabdo- and Filoviruses, Editors: A. K. Pattnaik and

M. A. Whitt, World Scientific, p. 311-334.

 

2013

I. Steffen, N.M. Liss, B.S. Schneider, J.N. Fair, C.Y. Chiu, G. Simmons. (2013)

Characterization of the Bas-Congo virus glycoprotein and its function in

pseudotyped viruses. J Virol. Sep;87(17):9558-68.

 

B. Salvador, N.R. Sexton, R. Carrion Jr., J. Nunneley, J.L. Patterson, I. Steffen,

K. Lu, M.O. Muench, D. Lembo, G. Simmons. (2013) Filoviruses utilize

glycosamino-glycans for their attachment to target cells. J Virol.

Mar;87(6):3295-304.

 

D. Lindemann, I. Steffen, S. Pöhlmann. (2013) Cellular entry of retroviruses.

Adv Exp Med Biol. 790:128-49.

 

2012

M. Kiene, A. Marzi, A. Urbanczyk, S. Bertram, T. Fisch, I. Nehlmeier, K. Gnirß,

C.B. Karsten, D. Palesch, J. Münch, F. Chiodi, S. Pöhlmann, I. Steffen. (2012)

The role of the alternative coreceptor GPR15 in SIV tropism for human cells.

Virology. Nov 10;433(1):73-84.

 

G. Grard, J.N. Fair, D. Lee, E. Slikas, I. Steffen, J.-J. Muyembe, T. Sittler,

N. Veeraraghavan, J.G. Ruby, C. Wang, M. Makuwa, P. Mulembakani, R.B. Tesh,

J. Mazet, A.W. Rimoin, T. Taylor, B.S. Schneider, G. Simmons, E. Delwart,

N.D. Wolfe, C.Y. Chiu, E.M. Leroy. (2012) A Novel Rhabdovirus Associated with

Acute Hemorrhagic Fever in Central Africa. PLoS Pathog. Sep;8(9):e1002924.

 

D. Lee, J. Das Gupta, C. Gaughan, I. Steffen, N. Tang, K.-C. Luk, X. Qiu, A. Urisman,

N. Fischer, R. Molinaro, M. Broz, G. Schochetman, E.A. Klein, D. Ganem, J.L. DeRisi,

G. Simmons, J. Hackett, R.H. Silverman, C.Y. Chiu. (2012) In-Depth Investigation of

Archival and Prospectively Collected Samples Reveals No Evidence for XMRV

Infection in Prostate Cancer. PLoS One 7(9):e44954.

 

Y. Zhou, I. Steffen, L. Montalvo, T.-H. Lee, R. Zemel, W.M. Switzer, S. Tang, H. Jia,

W. Heneine, V. Winkelman, C.S. Tailor, Y. Ikeda, G. Simmons. (2012) Development

and Application of a High-Throughput Micro-Neutralization Assay - Lack of

XMRV/MLV Detection in Blood Donors. Transfusion. Feb;52(2):332-42.

 

2011

S. Bertram*, I. Glowacka*, M.A. Müller*, H. Lavender, K. Gnirss, G. Simmons,

C. Drosten, E.J. Soilleux, I. Steffen, S. Pöhlmann. (2011) Cleavage and activation

of the SARS-coronavirus spike-protein by human airway trypsin-like protease

(HAT). J Virol. Dec;85(24):13363-72.

 

A. Kühl, C. Banning, A. Marzi, J. Votteler, I. Steffen, S. Bertram, I. Glowacka,

A. Konrad, M. Stürzl, J.-T. Guo, U. Schubert, H. Feldmann, G. Behrens,

M. Schindler, S. Pöhlmann. (2011) The Ebola Virus Glycoprotein and HIV-1

Vpu Employ Different Strategies to Counteract the Antiviral Factor Tetherin.

J Infect Dis. 2011 Nov;204 Suppl 3:S850-60.

 

S. Pfefferle, J. Schöpf, M. Kögl, C.C. Friedel, M.A. Müller, J. Carbajo-Lozoya,

T. Stellberger, E. von Dall'armi, P. Herzog, S. Kallies, D. Niemeyer, V. Ditt, T. Kuri,

R. Züst, K. Pumpor, R. Hilgenfeld, F. Schwarz, R. Zimmer, I. Steffen, F. Weber,

V. Thiel, G. Herrler, H.J. Thiel, C. Schwegmann-Weßels, S. Pöhlmann, J. Haas,

C. Drosten, A. von Brunn. (2011) The SARS-Coronavirus-Host Interactome:

Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors.

PLoS Pathog. Oct;7(10):e1002331.

 

I. Steffen, D.L. Tyrrell, E. Stein, L. Montalvo, T.H. Lee, Y. Zhou, K. Lu, W.M. Switzer,

S. Tang, H. Jia, D. Hockman, D.M. Santer, M. Logan, A. Landi, J. Law, M. Houghton,

G. Simmons. (2011) No evidence for XMRV nucleic acids, infectious virus or anti-

XMRV antibodies in Canadian patients with chronic fatigue syndrome. PLoS One.

6(11):e27870.

 

Z. Pipirou, A.S. Powlesland, I. Steffen, S. Pöhlmann, M.E. Taylor, K. Drickamer.

(2011) Mouse LSECtin as a model for a human Ebola virus receptor.

Glycobiology. Jun;21(6):806-12.

 

G. Simmons, S. Bertram, I. Glowacka, I. Steffen, C. Chaipan, J. Agudelo, K. Lu,

A.J. Rennekamp, H. Hofmann, P. Bates, S. Pöhlmann. (2011) Different host cell

proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell

fusion. Virology. May 10;413(2):265-74.

 

I. Glowacka*, S. Bertram*, M.A. Müller, P. Allen, E. Soilleux, S. Pfefferle, I. Steffen,

T.S. Tsegaye, Y. He, K. Gnirss, D. Niemeyer, H. Schneider, C. Drosten, S. Pöhlmann.

(2011) Evidence that TMPRSS2 activates the severe acute respiratory syndrome

coronavirus spike protein for membrane fusion and reduces viral control by the

humoral immune response. J Virol. May;85(9):4122-34.

 

2010

S. Bertram*, I. Glowacka*, P. Blazejewska, E. Soilleux, P. Allen, S. Danisch,

I. Steffen, S.Y. Choi, Y. Park, H. Schneider, K. Schughart, S. Pöhlmann. (2010)

TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza

virus in Caco-2 cells. J Virol. Oct;84(19):10016-25.

 

M. Peters, M. Kauth, O. Scherner, K. Gehlhar, I. Steffen, P. Wentker,

E. von Mutius, O. Holst, A. Bufe. (2010) Arabinogalactan isolated from

cowshed dust extract protects mice from allergic airway inflammation

and sensitization. J Allergy Clin Immunol. Sep;126(3):648-56.e1-4.

 

S. Bertram, I. Glowacka, I. Steffen, A. Kühl, S. Pöhlmann. (2010) Novel insights

into proteolytic cleavage of influenza virus hemagglutinin. Rev Med Virol.

Sep;20(5):298-310.

 

C. Chaipan*, I. Steffen*, T.S. Tsegaye*, S. Bertram, I. Glowacka, Y. Kato,

J. Schmökel, J. Münch, G. Simmons, R. Gerardy-Schahn, S. Pöhlmann. (2010)

Incorporation of podoplanin into HIV released from HEK-293T cells,

but not PBMC, is required for efficient binding to the attachment factor CLEC-2.

Retrovirology. May 19;7:47. 

 

I. Steffen, S. Pöhlmann. (2010) Peptide-based inhibitors of the HIV envelope

protein and other class I viral fusion proteins. Curr Pharm Des. 16(9):1143-58.

 

I. Steffen, T.S. Tsegaye, S. Pöhlmann. (2010) Lectin-like interactions in virus-cell

recognition: human immunodeficiency virus and C-type lectin interactions. In

Microbial Glycobiology: Structures, Relevance and Applications, Elsevier

Science, p. 567-584.

 

A. Kühl, J. Münch, D. Sauter, S. Bertram, I. Glowacka, I. Steffen, A. Specht,

H. Hofmann, H. Schneider, G. Behrens, S. Pöhlmann. (2010) Calcium-modulating

cyclophilin ligand does not restrict retrovirus release. Nat Med. Feb;16(2):155-6.

 

I. Glowacka*, S. Bertram*, P. Herzog, S. Pfefferle, I. Steffen, M.O. Muench,

G. Simmons, H. Hofmann, T. Kuri, F. Weber, J. Eichler, C. Drosten, S. Pöhlmann.

(2010) Differential downregulation of ACE2 by the spike proteins of severe

acute respiratory syndrome coronavirus and human coronavirus NL63. J Virol.

Jan;84(2):1198-205.

 

2009

C. Chaipan*, D. Kobasa*, S. Bertram*, I. Glowacka, I. Steffen, T.S. Tsegaye,

M. Takeda, T.H. Bugge, S. Kim, Y. Park, A. Marzi, S. Pöhlmann. (2009) Proteolytic activation of the 1918 influenza virus hemagglutinin. J Virol. Apr;83(7):3200-11.

Kontakt
Dr. Tina Basler
Tel.:+49 511 953-6141
Fax.:+49 511 953-8675
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