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Sie sind hier:

Dr. Imke Steffen

Address:         Department of Physiological

                         Chemistry / Research Center

                         for Emerging Infections

                         and Zoonoses

                         University of Veterinary Medicine

                         Bünteweg 17

                         30559 Hannover, Germany

 

Phone:            +49 (0)511 953 6112

Fax:                  +49 (0)511 953 8585

E-mail:            imke.steffen@tiho-hannover.de

 

Current

position:         Junior Research Group Leader

 

                         The project is funded by the

                         Federal Ministry of Education

                         and Research (BMBF)

 

Family obligations:   1 child

 

 

Research Positions:

07/2017 – present         Junior Research Group Leader,

                                           Institute for Physiological Chemistry and

                                          Research Center for Emerging Infections and Zoonoses,

                                          University of Veterinary Medicine, Hannover, Germany

                                 -        Identification of host-specific mechanisms of protection

                                          against arthropod-borne flaviviruses

                                 -        Comparative analyses of flavivirus pathogenesis in different

                                          host species

 

02/2011 – 06/2017        Postdoctoral Fellow in the Laboratory of Dr. Graham Simmons,

                                          Blood Systems Research Institute and Laboratory Medicine,

                                          University of California San Francisco, CA

                               -          Establishment of pseudotype and reverse genetics systems for

                                          new and emerging RNA viruses

                               -          Identification of viral attachment and receptor molecules

                               -          High-throughput screening of serum samples for neutralizing

                                          antibodies targeting hemorrhagic fever viruses

 

10/2007 – 01/2011        PhD Candidate in the Laboratory of Prof. Stefan Pöhlmann,

                                          Department of Virology, Hannover Medical School, Germany

                               -          Inhibition of HIV capsid assembly by small molecule

                                          compounds

                                          identified in a cell-free protein synthesis screen

                               -          HIV cell-to-cell transmission by cellular lectins

                               -          Alternative co-receptors for SIV cell entry into human cells

                               -          Proteolytic activation of the viral envelope proteins of SARS

                                          coronavirus and influenza A virus

 

05/2006 – 09/2007        M.Sc. Graduate Student and Research Assistant in the

                                          Laboratory of Prof. Albrecht Bufe, Department of Experimental

                                          Pneumology, Ruhr-University Bochum, Germany:

                               -          Identification of immunomodulatory substances in stable dust

                                          extracts and their effect on the development of allergic asthma

 

 

EDUCATION

10/2007 - 01/2011         PhD in Infection Biology, Institute of Virology, Hannover Medical

                                          School, Hannover, Germany. Advisor: Prof. Stefan Pöhlmann,

                                          Thesis: "Identification and characterization of HIV capsid

                                          assembly inhibitors", summa cum laude (excellent)

 

08/2005 - 04/2007         M.Sc. in Biochemistry, Experimental Pneumology, Ruhr-

                                          University Bochum, Bochum, Germany. Advisor: Prof. Albrecht

                                          Bufe, Thesis: "Identification of immunomodulatory substances

                                          in stable dust extracts", (excellent)

 

10/2004 - 07/2005         ERASMUS Program for European Student Exchange, University

                                          of Coimbra, Coimbra, Portugal

 

10/2001 - 09/2004         B.Sc. in Biochemistry, Ruhr-University Bochum, Germany and

                                          Max-Planck Institute of Molecular Physiology, Dortmund,

                                          Germany. Advisor: Dr. Eva Wolf, Thesis: "Expression,

                                          purification and crystallization of the Drosophila period protein".

 

 

Awards and Fellowships

-     Postdoctoral Research Fellowship, German Research Foundation

      (Deutsche Forschungsgemeinschaft, DFG) (July 2013 - June 2016)

 

-     PhD Prize for Outstanding Contribution to the Field of Infection Biology, Hirte

      Foundation (January 2011) Imke Steffen, PhD Curriculum Vitae

 

-     First Prize Oral Presentation, PhD program "Infection Biology", 2nd Retreat,

      Hannover Medical School, Germany (February 2010)

 

-     Young Investigator Award, 17th Conference on Retroviruses and Opportunistic

      Infections, San Francisco, CA (February 2010)

 

-     Poster prize, Master Class of Virology, Hannover Medical School, Germany

      (November 2009)

 

-     Young Investigator Award, 16th Conference on Retroviruses and Opportunistic

       Infections, Montreal, Canada (February 2009)

 

-     Infection Biology PhD Fellowship, Hannover Medical School, Germany

      (October 2007 - January 2011)

 

 

Additional skills and training:

Dec 2014 and Feb 2015      Scientific Leadership and Management Course,

                                                  University of California San Francisco, San Francisco, CA

 

November 2008                    Research Skills Development Course, Helmholtz

                                                 Association and Imperial College London

 

July 2008                                 Communication and Presentation Skills, Helmholtz

                                                  Association and Imperial College London

 

2007 - present                       Extensive experience in biosafety level 3 operating

                                                  procedures, Hannover Medical School, Germany, Blood

                                                  Systems Research Institute, San Francisco, CA and

                                                  University of Veterinary Medicine, Hannover, Germany

 

April 2006                                Technical Qualification Course in Radiation Safety,

                                                  Central Isotope Laboratory, Ruhr-University Bochum,

                                                  Germany

 

 

Presentations:

National Symposium on Zoonoses Research, Berlin, Germany, October 2017. "Emerging RNA viruses and their interaction with the human and animal host", Poster Presentation

 

35th Annual Meeting of the American Society for Virology, Blacksburg, VA, June 2016. "Serological prevalence of hemorrhagic fever viruses in Equatorial Africa", Oral Presentation

 

26th Annual Meeting of the German Society for Virology, Münster, Germany, April 2016. "Serological prevalence of hemorrhagic fever viruses in Equatorial Africa", Oral Presentation

 

33rd Annual Meeting of the American Society for Virology, Fort Collins, CO, June 2014. "Serological evidence for human Bas-Congo virus exposure in the Republic of the Congo", Oral Presentation

 

62nd Annual Meeting of the American Society of Tropical Medicine and Hygiene, Washington, DC, Nov. 2013. "Characterization of the Bas-Congo virus glycoprotein

and its function and use in pseudotyped viruses", Poster Presentation

 

1st Bay Area Symposium on Viruses, UC Berkeley, May 2011. "Identification and characterization of HIV capsid assembly inhibitors", Poster Presentation

 

Infection Biology Retreat, Hannover Medical School, Germany, Feb 2010. "Identification of HIV capsid assembly inhibitors", Oral Presentation

 

17th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA,

Feb 2010. "Identification of HIV capsid assembly inhibitors", Poster Presentation

 

16th Conference on Retroviruses and Opportunistic Infections, Montreal, Canada,

Feb 2009. "Analysis of HIV-1 inhibition by an anionic polysaccharide isolated from the cyanobacterium Arthrospira platensis" and "HIV-1 transmission by platelets", Poster Presentation

 

18th Annual Meeting of the German Society for Virology, Heidelberg, Germany, Mar 2008. "HIV transmission by platelets", Poster Presentation

 

 

Other contributions and memberships:

  • Member of the Advisory Board of the German Research Platform for Zoonoses
  • Session Chair at the 35th Annual Meeting of the American Society for Virology, 2016
  • Head of the Organizing Committee for the BSRI Retreat 2014
  • Ad-hoc Reviewer for PLoS One Open Access Journal
  • Member of the American Society for Virology (ASV) since 2014
  • Member of the International Society for Infectious Diseases (ISID) since 2011
Kontakt
Dr. Tina Basler
Tel.:+49 511 953-6141
Fax.:+49 511 953-8675
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