2021

Hoffmann P, Schnepel N, Langeheine M, Künnemann K, Grassl GA, Brehm R, Seeger B, Mazzuoli-Weber G, Breves G (2021) Intestinal organoid-based 2D monolayers mimic physiological and pathophysiological properties of the pig intestine. PLoS One 16(8):e0256143 doi:10.1371/journal.pone.0256143

Schenke M., Prause H.-C., Bergforth W., Przykopanski A., Rummel A., Klawonn F., Seeger B (2021) Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1. Toxins (Basel) 13(8):585 doi:10.3390/toxins13080585

Kostka, T., Empl, M. T., Seiwert, N., Geisen, S. M., Hoffmann, P., Adam, J., Seeger, B., Shay, J. W., Christmann, M., Sturla, S. J., Fahrer, J., & Steinberg, P. (2021). Repair of O6-carboxymethylguanine adducts by O6-methylguanine-DNA methyltransferase in human colon epithelial cells. Carcinogenesis, bgab049. Advance online publication. doi:10.1093/carcin/bgab049

Schmitz A, Dempewolf S, Tan S, Bicker G, Stern M. Developmental neurotoxicity of fipronil and rotenone on a human neuronal in vitro test system. Neurotox. Res. 2021, epub ahead of print, doi:10.1007/s12640-021-00364-8

2020

Bode K, Bohn M, Reitmeier J, Betker P, Stern M, Bicker G. A locust embryo as predictive developmental neurotoxicity testing system for pioneer axon pathway formation. Arch Toxicol., 2020, 94: 4099-4113. doi:10.1007/s00204-020-02929-6

Bode K, Nolte L, Kamin H, Desens M, Ulmann A, Bergmann GA, Betker P, Reitmeier J, Ripken T, Stern M, Meyer H, Bicker G. Scanning laser optical tomography resolves developmental neurotoxic effects on pioneer neurons. Sci. Rep. 2020, 10:2641. doi:10.1038/s41598-020-59562-7

Bonilla MC, Fingerhut L, Alfonso-Castro A, Mergani A, Schwennen C, von Köckritz-Blickwede M, de Buhr N. How Long Does a Neutrophil Live?-The Effect of 24 h Whole Blood Storage on Neutrophil Functions in Pigs. Biomedicines. 2020, doi:10.3390/biomedicines8080278

Branitzki-Heinemann K, Brogden G, von Köckritz-Blickwede M. Influence of Oxygen on Function and Cholesterol Composition of Murine Bone Marrow-Derived Neutrophils. Methods Mol Biol, 2020, doi:10.1007/978-1-0716-0154-9_17

de Buhr N, von Köckritz-Blickwede M. Detection, Visualization, and Quantification of Neutrophil Extracellular Traps (NETs) and NET Markers. Methods Mol Biol, 2020, doi:10.1007/978-1-0716-0154-9_25.PMID: 31729003

Gericke B, Römermann K, Noack A, Noack S, Kronenberg J, Blasig I E, Löscher W. A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood-brain barrier models for drug transport studies. Fluids Barriers CNS, 2020, doi: 10.1186/s12987-020-00212-5

Heimes M, Tipold A, Dilly M. Simulationsbasierte Lehre in der tiermedizinischen Ausbildung – SWOT-Analyse eines Clinical Skills Lab. Berliner und Münchener Tierärztliche Wochenschrift, 2020, doi:10.2376/0005-9366-19019 ISSN 0005-9366

Hohlbaum K, Kral V, Zoschke C, Hiebl B, Schäfer-Korting M, Thöne-Reineke C. Open access webinars bring 3R experts to your web browser: The Berlin experience. ALTEX, 2020, doi:10.14573/altex.2002091

Knab R, Petersen H, Lin HJ, Meixner M, Rautenschlein SJung A. In vitro characterization and genetic diversity of Bordetella avium field strains. Avian Pathol. 2020;49(1):36‐46. doi:10.1080/03079457.2019.1660305

Mercer DK, Torres MDT, Duay SS, Lovie E, Simpson L, von Köckritz-Blickwede M, de la Fuente-Nunez C, O'Neil DA, Angeles-Boza AM. Antimicrobial Susceptibility Testing of Antimicrobial Peptides to Better Predict Efficacy. Front Cell Infect Microbiol, 2020, doi:10.3389/fcimb.2020.00326. eCollection 2020.

Mertens S, Gass P, Palme R, Hiebl B, Chorubaji S. Effect of a partial cage dividing enrichment on aggression-associated parameters in group-housed male C57BL/6NCrl mice. PLOS ONE, 2020, doi:10.1016/j.applanim.2020.104939

Mikolai C, Branitzki-Heinemann K, Ingendoh-Tsakmakidis A, Stiesch M, von Köckritz-Blickwede M, Winkel A. Neutrophils exhibit an individual response to different oral bacterial biofilms. J Oral Microbiol, 2020, doi:10.1080/20002297.2020.1856565

Proft L, Nehring ME, Gruber C, Sievers H, Hünigen H, Gemeinhardt O,  Kenneth C. Richardson KC, Hiebl B. Growth‐related micromorphological characteristics of the porcine common carotid artery. Anatomia histologia Embryologia, 2020, doi:10.1111/ahe.12522

Schenke M, Schjeide BM, Püschel GP, Seeger B. Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays. Toxins (Basel). 2020;12(5):E276. Published 2020 Apr 25. doi:10.3390/toxins12050276

Seeger B. Farm Animal-derived Models of the Intestinal Epithelium: Recent Advances and Future Applications of Intestinal Organoids. Alternatives to Laboratory Animals, 2020, doi:10.1177/0261192920974026

Weber LA, Meißner J, Delarocque J, Kalbitz J, Feige K, Kietzmann M, Michaelis A, Paschke R, Michael J, Pratscher B, Cavalleri JV. Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro. BMC Vet Res. 2020 Feb 5;16(1):44. doi: 10.1186/s12917-020-2262-5

Weber LA, Funtan A, Paschke R, Delarocque J, Kalbitz J, Meißner J, Feige K, Kietzmann M, Cavalleri JV. In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate as a topical treatment for equine skin cancer. PLoS One. 2020 Nov 5;15(11):e0241448. doi: 10.1371/journal.pone.0241448

2019

Bergmann GA, Froembling S, Joseph N, Bode K, Bicker GStern M. An intact insect embryo for developmental neurotoxicity testing of directed axonal elongation. ALTEX. 2019;36(4):643‐649. doi:10.14573/altex.1901292

Bruer GG, Hagedorn P, Kietzmann M, Tohamy AF, Filor V, Schultz E, Mielke-Kuschow S, Meissner J. Histamine H1 receptor antagonists enhance the efficacy of antibacterials against Escherichia coli. BMC Vet Res. 2019 Feb 11;15(1):55. doi: 10.1186/s12917-019-1797-9

Nies A, Proft L, Nehring ME, Gruber C, Sievers H, Hünigen H, Rodrigues AG, Gemeinhardt O, Mrowitz C, Jung F, Hiebl B. Growth-related micromorphological characteristics of the porcine femoral artery.  Clinical Hemorheoplghy and Microcirculation, 2019, doi: 10.3233/CH-199219

Meng F, Tong J, Vötsch D, ... Herrler G,..., Valentin-Weigand P. Viral Coinfection Replaces Effects of Suilysin on Streptococcus suis Adherence to and Invasion of Respiratory Epithelial Cells Grown under Air-Liquid Interface Conditions. Infect Immun. 2019;87(8):e00350-19. Published 2019 Jul 23. doi:10.1128/IAI.00350-19

Mertens S, Vogt MA, Gass P, Palme R, Hiebl B, Chourbaji S.  Effect of three different forms of handling on the variation of aggression-associated parameters in individually and group-housed male C57BL/6NCrl mice. PLOS ONE, 2019, doi:10.1371/journal.pone.0215367

Müller LR, Tipold A, Ehlers JP, Schaper E. TiHoVideos: veterinary students' utilization of instructional videos on clinical skills. BMC Vet Res. 2019;15(1):326. Published 2019 Sep 11. doi:10.1186/s12917-019-2079-2

Seeger, B. Implementing Data - The Future of Alternative Methods - VZET Symposium 2019. Altex, 36(3), 477-478. doi:10.14573/altex.1906211

Seeger B, Mentz A, Knebel C, et al. Assessment of mixture toxicity of (tri)azoles and their hepatotoxic effects in vitro by means of omics technologies. Arch Toxicol. 2019;93(8):2321‐2333. doi:10.1007/s00204-019-02502-w

Weldearegay YB, Müller S, Hänske J, ..., Valentin-Weigand P et al. Host-Pathogen Interactions of Mycoplasma mycoides in Caprine and Bovine Precision-Cut Lung Slices (PCLS) Models. Pathogens. 2019;8(2):82. Published 2019 Jun 20. doi:10.3390/pathogens8020082

Winter C, Kosch R, Ludlow M, Osterhaus ADME, Jung K. Network meta-analysis correlates with analysis of merged independent transcriptome expression data. BMC Bioinformatics. 2019;20(1):144. Published 2019 Mar 15. doi:10.1186/s12859-019-2705-9

Wissing S. Tierschutz in der tierärztlichen Ausbildung und Zentrum für klinische Fertigkeiten (Clinical Skills Lab) an der Tierärztlichen Hochschule Hannover. In: J. HARTUNG, M. PARANHOS DA COSTA u. C. PEREZ (Hrsg.): Tierschutz in Deutschland und Brasilien - Verantwortung und Leidenschaft. Deutsch-Brasilianische Industrie- und Handelskammer in São Paulo, 2019, Link

2018

Baien SH, Langer MN, Heppelmann M, von Köckritz-Blickwede M, de Buhr N. Comparison Between K3EDTA and Lithium Heparin as Anticoagulant to Isolate Bovine Granulocytes From Blood. 2018, Front Immunol. doi:10.3389/fimmu.2018.01570. eCollection 2018.

Gruber, C., Seeger, B., Mrowietz, C, Gemeinhardt, O, Plendl, J, Hiebl, B. Importance of alternative methods for animal testing in the context of conformity assessment of medical devices. 2018; Berliner und Munchener Tierarztliche Wochenschrift. doi:10.2376/0005-9366-17107

Kleinsorgen Cvon Köckritz-Blickwede MNaim HY, ..., Tipold A et al. Impact of Virtual Patients as Optional Learning Material in Veterinary Biochemistry Education. J Vet Med Educ. 2018;45(2):177‐187. doi:10.3138/jvme.1016-155r1

Kruppa J, Lepenies BJung K. A genetic algorithm for simulating correlated binary data from biomedical research. Comput Biol Med. 2018;92:1‐8. doi:10.1016/j.compbiomed.2017.10.023

Noack A, Gericke B, von Köckritz-Blickwede M, Menze A, Noack S, Gerhauser I, Osten F, Naim H Y, Löscher W. Mechanisms of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils. Proc Natl Acad Sci U S A, 2018, doi: 10.1073/pnas.1719642115.

Tong J, Fu Y, Wu NH, ... Valentin-Weigand PHerrler G. Sialic acid-dependent interaction of group B streptococci with influenza virus-infected cells reveals a novel adherence and invasion mechanism. Cell Microbiol. 2018;20(4):10.1111/cmi.12818. doi:10.1111/cmi.12818