Genomics and Bioinformatics of Infectious Diseases

Group head
Prof. Dr. Klaus Jung

Staff & PhD students:
Shamini Hemandhar Kumar, M.Sc.
Magdalena Kircher, M.Sc.
Moritz Kohls, M.Sc.
Jessica Krepel, M.Sc.
Babak Saremi, M.Sc.
Michael Selle, M.Sc.
Christine Winter, M.Sc., Veterinarian

Contents of our research

Our research group explores bioinformatics methods for analysing biological data from high-throughput experiments. In these experiments, e.g. next-generation sequencing or DNA microarray technology is used to determine the expression of thousands of genes simultaneously or genome sequences of entire organisms. In our method development, we particularly consider robust procedures or those that aim at a high reproducibility of results. We use classical statistical methods, such as resampling methods or methods of evidence synthesis (e.g. meta-analyses or the fusion of several independent data sets), and adapt them for bioinformatics purposes. Our methods focus in particular on applications in infection research. One main application is viral metagenomics, i.e. the detection of viral sequences in biological samples of infected hosts. In addition, we maintain further collaborations with scientists from various fields of biology and medicine, and develop our bioinformatics methods further in these projects. A list of externally funded projects can be found at the bottom of this page. A list of publications can be found here.

Funded research projects

  • 2021-2024: BMEL EVOLECTION (System to Evolve productive sow herds by statistic, AI and sensor data driven selection of the tribal sows in criss-cross-breeding)
  • 2020-2024: EU SMABEYOND (Spinal Muscular Atrophy (SMA) beyond motoneuron degeneration: multi-system aspects)
  • 2019-2022: FibrOmics (Translating Omics studies into clinically relevant insights for lung fibrosis patients)
  • 2019-2023: DFG GRK 2485 VIPER (Virus detection, pathogenesis and intervention)
  • 2019-2021: DigiStep (Digitalisierungsschritte von Lehrinhalten im Tiermedizinstudium)
  • 2016-2018: N-RENNT (Niedersachsen-Research Network on Neuroinfectiology)
  • 2017-2018: BMBF GlykoViroLectinTools (Etablierung von Lektin-Bibliotheken aus Mensch, Schaf und Stechmücken – eine neue Plattform für Bindungsstudien mit viralen Glykoproteinen am Beispiel des Rifttalfiebers)

For further information in the projects please look at the TiHo database for research projects

Job postings, doctoral opportunities and topics for theses

We regularly offer positions for employees who have a degree in bioinformatics or a comparable subject. Please feel free to contact us at any time regarding open positions and doctoral opportunities (also for veterinarians), as well as topics for bachelor's or master's theses. (E-Mail: klaus.jung(at)tiho-hannover.de or Telephone: 0511 953-8878).

Study material

Interactive graphics for teaching veterinary medicine (only accessible from a TiHo PC):

http://zucht-biolinux2:3838/sample-apps/website/