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Research

Food Toxicology:

 

Molecular mechanisms of colon cancer formation

  • Endogenously formed N-nitroso compounds from red meat: Potential to contribute to malignant transformation of human colon epithelial cells and underlying mechanisms
  • Intestinal bacteria-mediated formation of N-nitroso compounds from red meat and their potential to contribute to malignant transformation of human colon epithelial cells

  • The role of the bacterial pathogen Streptococcus gallolyticus ssp. gallolyticus in colon cancer formation

 Risk assessment of genetically modified maize

  • Safety assessment of genetically modified maize NK603

 Bioanalytics and Metabolomics

  • Analytics of parasitic fatty acid pattern by means of gas chromatography

  • Impact of food ingredients and contaminants on endogenous inflammation mediators - Targeted metabolomics of the eicosanoid pathway

Alternative and Complementary Methods for Animal Testing:

Development of Alternative and Complementary Methods for Animal Testing

  • Development of an in vitro assay for the evaluation of Botulinum toxin activity based on transgenic human stem cells

  • Development of a transformation assay based on human epithelial cells

  • Development of an in vitro model for the investigation of pathogenic mechanisms of intestinal disorders caused by zoonotic agents

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