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Veterinary medicine

Lecture: Biochemistry I

Course for the 2nd semester, V 572

 

Contents:

  • Amino acids and protein chemical basics
  • Function and appearance of proteins
  • Enzymes and their function in metabolism, co-enzymes, vitamins
  • Chemistry of carbohydrates: characteristics and relevance
  • Glucose breakdown in glycolysis, fermentation
  • Pyruvat dehydrogenase complex and citric acid cycle
  • Respiratory chain and oxidative phosphorylation
  • Degradation of carbohydrates in the rumen
  • Nucleotide biosynthesis
  • Replication, transcription und translation

 

Periods:

  • Mo 2-3 pm, Do 9-10 am, Fr 8-9 am

Lecture: Biochemistry II

Course for the 3rd semester, V 79

 

Contents:

  • Chemistry of lipids: composition and characterisation
  • Synthesis, transport, metabolism and degradation of lipids
  • Isoprenoids, cholesterol, bile acid, steroid hormones, eicosanoids and biogenic amines
  • Protein degradation, deamination, urea cycle
  • Metabolism disorders and regulation
  • Ketogenesis, gluconeogenesis, glycogen metabolism, diabetes
  • Topo biochemistry: cellular organelles and structure of the cell
  • Protein modification und trafficking in the cell
  • Peptide hormones and signal transduction

 

Periods:

  • Mo. 11.15 - 12 am Physiologie-Hörsaal, Bischofsholer Damm
  • Di. 2.15 - 3 pm Bayer-Hörsaal, Bünteweg
  • Fr. 8.00 - 8.45 am Bayer-Hörsaal, Bünteweg

Practical course: Biochemical exercises

Course for the 2nd semester, Ü 574

 

The biochemical exercises take place each as one week full day block course in the lecture free time before beginning of the 3rd semester.

The students will be divided into three groups. The division will be set centrally by the student administration in accordance with the Ruthe-courses. For each group the practical course will last one week.

 

Topics of experiments:

  1. Separation of an amino acid mixture through ion exchange chromatography and quantitative analysis of amino acids
  2. Determination of collagen over hydroxyproline
  3. Optical test of Warburg I
  4. Optical test of Warburg II
  5. Accumulation of glycoproteins from Caco-2 cells by precipitation with the lectin concanavalin A and the detection of enzymatic activity of saccharase isomaltase
  6. Isolation and restriction mapping of plasmids
  7. Gender determination by polymerase chain reaction (PCR)

 

Each student needs to absolve the seven exercises to the times and in the order which will be displayed before the course onset. The exercises start daily at 9 am (c.t.) and continue until ca. 5 pm.

 

On Monday morning takes place at first a safety briefing for each whole group. Furthermore will the course books be handed out. The following exercises take place partly in the course room of the pharmacology and partly in Lehrgebäude I.

Compulsory course: molecular pathomechanisms

Course for the 4th semester, WP 2502

 

Maximum 20 participants work out oral presentations on the subject of molecular pathomechanisms such as for BSE, Alzheimers disease, mitochondria pathies, lysosomal storage disease, colitis or food stuff intolerance. There for 14 SWS will be credited in the subject of aetiology.

 

The seminar starts 2015 on the 14th April with a preliminary discussion and the oral presentations will be held weekly from 12th May on. Start is 2 pm (c.t.) in the seminar room of the institute.

Summer School of the centre of infection medicine

Course for the 6th/8th semester

 

As member of the centre of infection medicine provides the institute of biochemistry annually a two to three month project orientated practical lab course in the lecture free time from July until October, which will be funded by a scholarship from the institute.

 

Details should be taken from separate notices.

Beyond the regular course offer it is possible to do individual practical lab courses (e.g. in the practical year) as well as working on a dissertation. Information on available projects as well as support for application for scholarships will be provided on request.

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