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Dr. Nicole de Buhr

Nicole de Buhr, PhD studied from 2006 to 2012 veterinary medicine at University of Veterinary Medicine Hannover. During this time she did several internships in research institutions. She worked for example two month in the Institute of Virology with influenza virus. Furthermore, she did a two month internship at the Federal Research Institute for Animal Health (FLI) Riems in Institute of Infectology and Department of Experimental Animal Facilities and Biorisk Management where she worked with fish cell culture, fish pathogens (e.g. herpesvirus CyHV-1) and Influenza-A-Virus. Afterwards she worked for 4 month at the Institute for Microbiology on an immunoproteomic approach with Streptococcus suis.

She performed her PhD thesis about “Interaction of Streptococcus suis and neutrophil extracellular traps (NETs)” at the University of Veterinary Medicine Hannover in the Institute for Microbiology. In November 2015 she received her PhD title and in 2016 her PhD thesis was awarded with the Gerhard-Domagk Award for Life Sciences.

Since October 2015 she has been a member of the Infection Biochemistry research group at the Institute of Physiological Chemistry at the University of Veterinary Medicine in Hannover. Her research area of interest is “The function of neutrophil extracellular traps (NETs) in different animal species” with a focus on

·         NETs in immune-privileged compartments

·         Significance of NETs in autoimmune diseases

·         Infectious diseases and NET formation

Publications (since 2014)

de Buhr, N., Reuner, F., Neumann, A., Stump-Guthier, C., Tenenbaum, T., Schroten, H., Ishikawa, H., Müller, K., Beineke, A., Valentin-Weigand, P., Hennig-Pauka, I., Gutsmann, T., Baums, C.G. and von Köckritz-Blickwede, M. (2016) “Neutrophil extracellular trap formation after transmigration of neutrophils through Streptococcus suis infected human choroid plexus epithelial cell barrier.” Cellular Microbiology, doi:10.1111/cmi.12649


Branitzki-Heinemann, K., Möllerherm, H., Völlger, L., Husein, D. M., de Buhr, N., Blodkamp, S., Reuner, F., Brogden, G., Naim, H. Y. & von Köckritz-Blickwede, M. (2016) "Formation of Neutrophil Extracellular Traps under Low Oxygen Level." Front Immunol 7, 1–9.


de Buhr, N. and von Köckritz-Blickwede, M. (2016) „How neutrophil extracellular traps (NETs) become visible.“ Journal of Immunology Research, vol. 2016, Article ID 4604713, DOI:10.1155/2016/4604713


Jerjomiceva, J., Seri, H., Yaseen, R., de Buhr, N., Setzer, W.N., Naim, H.Y. and von Köckritz-Blickwede, M. (2016) “Guarea kunthiana Bark Extract Enhances the Antimicrobial Activities of Human and Bovine Neutrophils.” Natural Product Journal, vol. 11, No. 6, pages 767-770. ISBN 1555-9475


de Buhr, N., Stehr, M., Neumann, A., Naim, H.Y., Valentin-Weigand, P., von Köckritz-Blickwede, M. and Baums, C.G. (2015) “Identification of a novel DNase of Streptococcus suis (EndAsuis) important for neutrophil extracellular trap degradation during exponential growth.”

Microbiology 161: 838–850. DOI 10.1099/mic.0.000040   


de Buhr, N., Neumann, A., Jerjomiceva, N., von Köckritz-Blickwede, M. and Baums, C.G. (2014) “Streptococcus suis DNase SsnA contributes to degradation of neutrophil extracellular traps (NETs) and evasion of NET-mediated antimicrobial activity.” Microbiology 2014 160: 385–95. DOI 10.1099/mic.0.072199-0 [Editor’s choice]



2016    First prize “Verständliche Wissenschaft” for the talk „Immunsystem gegen Bakterien – Begegnung auf Augenhöhe?“ den elften Wettbewerb des Helmholtz-Zentrums Geesthacht (HZG)


2016    Poster prize (3rd place) Zoonosensymposium 2016 - German Symposium on Zoonoses Research 2016, Berlin, for the poster “Neutrophil extracellular traps in the Streptococcus suis infected cerebrospinal fluid compartment.


2016    Prize for the best talk of a young scientist, DVG Meeting Bacteriology and Mycology, Jena, 2016 for the talk “Neutrophil extracellular traps in the Streptococcus suis infected cerebrospinal fluid compartment”


2016    Gerhard-Domagk Award for Life Sciences, University of Veterinary Medicine Hannover, for the PhD Thesis “Interaction of Streptococcus suis and Neutrophil extracellular traps (NETs)”


2016    Poster prize Third International Workshop of Veterinary Neuroscience, for the poster “Neutrophil extracellular traps (NET) in the Streptococcus suis-infected cerebrospinal fluid compartment


2014    Poster prize (3rd place) Zoonosensymposium 2014 - Joint Conference: German Symposium on Zoonoses Research 2014 and 7th International Conference on Emerging Zoonoses, Berlin, for the poster “Comparison of two neutrophil extracellular trap (NET) evasion factors in Streptococcus suis”

Tel.:+49 511 953-6119
Fax.:+49 511 953-8585
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