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CSF Facts

CHRONIC COURSE OF CLASSICAL SWINE FEVER VIRUS INFECTION

 

The chronic course of infection occurs when pigs are not able to develop an effective immune response against CSF virus. Initial signs of a chronic infection are similar to the acute infection. Later, predominately non-specific signs are present, intermittent fever, chronic enteritis and wasting. The typical haemorrhages of the skin are missing.

Animals can survive 2-3 months before their eventual death. CSFV is shed from the onset of clinical signs constantly until death. Antibodies may be temporarily detected in serum samples.

Pathological changes are less typical, especially concerning the lack of haemorrhages on organs and serosae. In animals showing chronic diarrhoea, necrotic lesion in the ileum, the ileocaecal valve and the rectum are common.

As clinical signs of chronic CSF are rather non-specific many other diseases must be considered for differential diagnosis. The increased body temperature is not necessarily present in every animal but in an infected pig holding fever can be detected at least in some animals.

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Acute

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Chronic

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Prenatal

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